eMedicine Specialties > Pediatrics: General Medicine > Infectious Disease

Catscratch Disease: Multimedia

Author: Allan D Friedman, MD, MPH, Chairman, Division of General Pediatrics, Dept of Pediatrics, Professor of Pediatrics, Virginia Commonwealth University, VCUH Health System
Contributor Information and Disclosures

Updated: Apr 28, 2009

Multimedia

Papulopustular lesions of a primary inoculation s...
(Enlarge Image)
Media file 1: Papulopustular lesions of a primary inoculation site on the hand of a 16-year-old patient. These lesions had been present for approximately 3 weeks. A catscratch antigen skin test was positive with 15-mm induration. No treatment was administered, and her condition spontaneously resolved in 2.5 months. Courtesy of Andrew Margileth, MD.
[ CLOSE WINDOW ]
Papulopustular lesions of a primary inoculation s...

Papulopustular lesions of a primary inoculation site on the hand of a 16-year-old patient. These lesions had been present for approximately 3 weeks. A catscratch antigen skin test was positive with 15-mm induration. No treatment was administered, and her condition spontaneously resolved in 2.5 months. Courtesy of Andrew Margileth, MD.

A crusted primary inoculation papule on the neck ...
(Enlarge Image)
Media file 2: A crusted primary inoculation papule on the neck of a 4-year-old child. Note the adjacent lymphadenitis. This patient had contact with cats and had multiple scratches. Courtesy of Andrew Margileth, MD.
[ CLOSE WINDOW ]
A crusted primary inoculation papule on the neck ...

A crusted primary inoculation papule on the neck of a 4-year-old child. Note the adjacent lymphadenitis. This patient had contact with cats and had multiple scratches. Courtesy of Andrew Margileth, MD.

This 13-year-old girl developed fatigue and malai...
(Enlarge Image)
Media file 3: This 13-year-old girl developed fatigue and malaise after being licked and scratched by a cat. The typical conjunctival granuloma was accompanied by a parotid mass and intraparotid adenitis. No treatment was administered, and all her signs and symptoms resolved in 3 months. Courtesy of Andrew Margileth, MD.
[ CLOSE WINDOW ]
This 13-year-old girl developed fatigue and malai...

This 13-year-old girl developed fatigue and malaise after being licked and scratched by a cat. The typical conjunctival granuloma was accompanied by a parotid mass and intraparotid adenitis. No treatment was administered, and all her signs and symptoms resolved in 3 months. Courtesy of Andrew Margileth, MD.

This 9-year-old boy developed catscratch disease ...
(Enlarge Image)
Media file 4: This 9-year-old boy developed catscratch disease (CSD) encephalitis and a papular pruritic dermatitis after sustaining cat scratches and developing regional lymphadenitis. He was in a coma for 4 days but experienced a complete and rapid recovery within 3 weeks. Biopsy of the skin rash revealed nonspecific changes. The CSD antigen skin test result was positive. Courtesy of Andrew Margileth, MD.
[ CLOSE WINDOW ]
This 9-year-old boy developed catscratch disease ...

This 9-year-old boy developed catscratch disease (CSD) encephalitis and a papular pruritic dermatitis after sustaining cat scratches and developing regional lymphadenitis. He was in a coma for 4 days but experienced a complete and rapid recovery within 3 weeks. Biopsy of the skin rash revealed nonspecific changes. The CSD antigen skin test result was positive. Courtesy of Andrew Margileth, MD.

This 2.5-year-old boy was recovering from catscra...
(Enlarge Image)
Media file 5: This 2.5-year-old boy was recovering from catscratch disease acquired 10 months before when he developed this neck abscess over a period of 3 weeks. Biopsy revealed caseating granulomas; acid-fast bacillus and Warthin-Starry stain results were negative. Courtesy of Andrew Margileth, MD.
[ CLOSE WINDOW ]
This 2.5-year-old boy was recovering from catscra...

This 2.5-year-old boy was recovering from catscratch disease acquired 10 months before when he developed this neck abscess over a period of 3 weeks. Biopsy revealed caseating granulomas; acid-fast bacillus and Warthin-Starry stain results were negative. Courtesy of Andrew Margileth, MD.

More on Catscratch Disease

Overview: Catscratch Disease
Differential Diagnoses & Workup: Catscratch Disease
Treatment & Medication: Catscratch Disease
Follow-up: Catscratch Disease
Multimedia: Catscratch Disease
References
[ CLOSE WINDOW ]

References

  1. Da Silva K, Chussid S. Cat scratch disease: clinical considerations for the pediatric dentist. Pediatr Dent. Jan-Feb 2009;31(1):58-62. [Medline].

  2. Chen TC, Lin WR, Lu PL, Lin CY, Chen YH. Cat scratch disease from a domestic dog. J Formos Med Assoc. Feb 2007;106(2 Suppl):S65-68. [Medline].

  3. Malatack JJ, Jaffe R. Granulomatous hepatitis in three children due to cat-scratch disease without peripheral adenopathy. An unrecognized cause of fever of unknown origin. Am J Dis Child. Sep 1993;147(9):949-53. [Medline].

  4. Cherinet Y, Tomlinson R. Cat scratch disease presenting as acute encephalopathy. Emerg Med J. Oct 2008;25(10):703-4. [Medline].

  5. ten Hove CH, Gubler FM, Kiezebrink-Lindenhovius HH. Back pain in a child caused by cat scratch disease. Pediatr Infect Dis J. Mar 2009;28(3):258. [Medline].

  6. Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis. Nov 15 2005;41(10):1373-406. [Medline].

  7. Anderson B, Sims K, Regnery R, et al. Detection of Rochalimaea henselae DNA in specimens from cat scratch disease patients by PCR. J Clin Microbiol. Apr 1994;32(4):942-8. [Medline].

  8. Bass JW, Vincent JM, Person DA. The expanding spectrum of Bartonella infections: II. Cat-scratch disease. Pediatr Infect Dis J. Feb 1997;16(2):163-79. [Medline].

  9. Batts S, Demers DM. Spectrum and treatment of cat-scratch disease. Pediatr Infect Dis J. Dec 2004;23(12):1161-2. [Medline].

  10. Bogue CW, Wise JD, Gray GF, Edwards KM. Antibiotic therapy for cat-scratch disease?. JAMA. Aug 11 1989;262(6):813-6. [Medline].

  11. Dalton MJ, Robinson LE, Cooper J, et al. Use of Bartonella antigens for serologic diagnosis of cat-scratch disease at a national referral center. Arch Intern Med. Aug 7-21 1995;155(15):1670-6. [Medline].

  12. Delahoussaye PM, Osborne BM. Cat-scratch disease presenting as abdominal visceral granulomas. J Infect Dis. Jan 1990;161(1):71-8. [Medline].

  13. Fox JW, Studley JK, Cohen DM. Recurrent expressive aphasia as a presentation of cat-scratch encephalopathy. Pediatrics. Mar 2007;119(3):e760-3. [Medline].

  14. Hajjaji N, Hocqueloux L, Kerdraon R, Bret L. Bone infection in cat-scratch disease: a review of the literature. J Infect. May 2007;54(5):417-21. [Medline].

  15. Hipp SJ, O'Shields A, Fordham LA, et al. Multifocal bone marrow involvement in cat-scratch disease. Pediatr Infect Dis J. May 2005;24(5):472-4. [Medline].

  16. Margileth AM. Dermatologic manifestations and update of cat scratch disease. Pediatr Dermatol. Feb 1988;5(1):1-9. [Medline].

  17. Margileth AM, Wear DJ, English CK. Systemic cat scratch disease: report of 23 patients with prolonged or recurrent severe bacterial infection. J Infect Dis. Mar 1987;155(3):390-402. [Medline].

  18. Peter, G, ed. Cat scratch disease. In: Red Book: Report of the Committee on Infectious Disease. 24th ed. 1997:165-6.

  19. Reynolds MG, Holman RC, Curns AT, et al. Epidemiology of cat-scratch disease hospitalizations among children in the United States. Pediatr Infect Dis J. Aug 2005;24(8):700-4. [Medline].

  20. Rolain JM, Chanet V, Laurichesse H, et al. Cat scratch disease with lymphadenitis, vertebral osteomyelitis, and spleen abscesses. Ann N Y Acad Sci. Jun 2003;990:397-403. [Medline].

  21. Spach DH, Koehler JE. Bartonella-associated infections. Infect Dis Clin North Am. Mar 1998;12(1):137-55. [Medline].

  22. Tolan RW Jr, Schibler KR, Galliani CA, Kleiman MB. Unusual systemic, pseudomalignant manifestations of cat-scratch disease in siblings. Pediatr Infect Dis J. Dec 1990;9(12):913-6. [Medline].

  23. Wong MT, Dolan MJ, Lattuada CP Jr, et al. Neuroretinitis, aseptic meningitis, and lymphadenitis associated with Bartonella (Rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1. Clin Infect Dis. Aug 1995;21(2):352-60. [Medline].

[ CLOSE WINDOW ]

Further Reading

[ CLOSE WINDOW ]

Keywords

catscratch disease, CSD, cat scratch disease, cat-scratch disease, cat bite, benign inoculation lymphoreticulosis, benign inoculation reticulosis, cat-scratch fever, regional granulomatous lymphadenitis, regional adenopathy, , , erythema nodosum, thrombocytopenia purpura, Parinaud oculoglandular syndrome, myelitis, transient peripheral neuropathy, retinitis, encephalitis, Bell palsy, hepatosplenic catscratch disease, endocarditis, rash, skin rash, abdominal pain, kitten bite, kitten scratch, treatment, diagnosis, back pain

[ CLOSE WINDOW ]

Contributor Information and Disclosures

Author

Allan D Friedman, MD, MPH, Chairman, Division of General Pediatrics, Dept of Pediatrics, Professor of Pediatrics, Virginia Commonwealth University, VCUH Health System
Allan D Friedman, MD, MPH is a member of the following medical societies: American Academy of Pediatrics
Disclosure: Nothing to disclose.

Medical Editor

Itzhak Brook, MD, MSc, Professor, Department of Pediatrics, Georgetown University School of Medicine
Itzhak Brook, MD, MSc is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians-American Society of Internal Medicine, American Federation for Clinical Research, American Medical Association, American Society for Microbiology, Armed Forces Infectious Diseases Society, Association of Military Surgeons of the US, Infectious Diseases Society of America, International Immunocompromised Host Society, International Society for Infectious Diseases, Medical Society of the District of Columbia, New York Academy of Sciences, Pediatric Infectious Diseases Society, Society for Ear, Nose and Throat Advances in Children, Society for Experimental Biology and Medicine, Society for Pediatric Research, Southern Medical Association, and Surgical Infection Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Joseph Domachowske, MD, Professor of Pediatrics, Microbiology and Immunology, Department of Pediatrics, Division of Infectious Diseases, State University of New York-Upstate Medical University
Joseph Domachowske, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American Society for Microbiology, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, and Phi Beta Kappa
Disclosure: Nothing to disclose.

CME Editor

Robert W Tolan Jr, MD, Chief, Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital; Clinical Associate Professor of Pediatrics, Drexel University College of Medicine
Robert W Tolan Jr, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Phi Beta Kappa, and Physicians for Social Responsibility
Disclosure: GlaxoSmithKline Honoraria Speaking and teaching; MedImmune Honoraria Speaking and teaching; Merck Honoraria Speaking and teaching; sanofi pasteur Honoraria Speaking and teaching; Baxter Healthcare Honoraria Speaking and teaching

Chief Editor

Russell W Steele, MD, Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine
Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association
Disclosure: None None None

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.