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Thoracic Discogenic Pain Syndrome

  • Author: Gerard A Malanga, MD; Chief Editor: Sherwin SW Ho, MD  more...
Updated: Dec 23, 2015


Thoracic disc herniation (TDH) is an uncommon and underreported entity that is often challenging to diagnose because of a relative paucity of examination findings and because of its nonspecific presentation. The number of patients with objective neurologic findings due to thoracic disc herniation is low, and most patients can be treated with a conservative approach without surgical intervention.[1, 2]




United States

Asymptomatic thoracic disc herniations are relatively common in the general population. Autopsy studies have shown that the prevalence rate ranges from 7-15%. The prevalence of asymptomatic disc herniations found radiographically varies with the imaging modality used. Awwad et al showed that 11-13% of asymptomatic subjects were found to have thoracic disc herniation on compute tomography (CT) myelograms,[3] whereas Wood et al showed 37% of such individuals were found to have thoracic disc herniation on magnetic resonance images (MRIs).[4]

Despite the relatively high frequency of asymptomatic disc herniations, symptomatic disc herniations occur in a range from 1 in 1000 to 1 in 1 million persons. The number of patients with objective neurologic findings due to thoracic disc herniation is thought to be closer to 1 in 1 million annually.

Although the frequency of thoracic discectomies is increasing, they are still performed much less frequently than discectomies in the cervical or lumbar regions. These procedures represent approximately 0.13-0.15% of admissions for disc disease and from 0.2% to 4% of all discectomies.


Functional Anatomy

The thoracic region of the spine is relatively inflexible and functions primarily to provide erect posture and assist in weight bearing of the trunk, head, and upper extremities during daily activities. The vertebral bodies are taller posteriorly than anteriorly, resulting in an anterior concavity and normal thoracic kyphosis.

In the thoracic spine, the addition of the sternum, the ribs, and their associated ligamentous structures provide additional support and rigidity. The 10 most superior ribs articulate anteriorly with the sternum and posteriorly with the transverse processes and vertebral bodies. These ribs are oriented vertically, with slight medial angulation in the coronal plane. This arrangement provides the thoracic spine with relatively good stability in the midsagittal plane. However, it also affords less stability in the lateral and rotational planes. Biomechanical studies have shown that thoracic intervertebral discs are most susceptible to injury when torsional and lateral forces are applied in tandem.

Several features of the thoracic spine increase its susceptibility to spinal cord compression associated with thoracic disc herniation, as follows:

  • The ratio of the spinal canal to the thoracic spinal cord is smaller than that found in the cervical and lumbar regions. Although the cross-sectional diameter of the thoracic cord is smaller than that of its cervical or lumbar counterparts, the diameter of the spinal canal is proportionally even smaller. Thus, the ratio of the spinal cord to the canal in the thoracic spine is 40%, whereas this ratio in the cervical spine is only 25%.
  • The dentate ligaments situated between the spinal cord and the nerve roots restrict posterior movement of the spinal cord within the canal. This makes the thoracic spine prone to vertical compression from anterior disc and bony prominences.
  • The natural kyphosis of the thoracic spine places the spinal cord in close proximity to the posterior longitudinal ligament and the posterior aspects of both the vertebral bodies and the discs in the thoracic region. This makes the thoracic cord especially susceptible to ventral compression from herniations.

Normal discs and disc degeneration

The 3 basic structures of normal vertebral discs are the nucleus pulposus, the annulus fibrosus, and the vertebral endplates. The nucleus pulposus is the gelatinous core of the disc and is composed mostly of water and proteoglycans. The annulus fibrosus surrounds the nucleus pulposus and is composed primarily of water and concentric layers of collagen. The vertebral endplates lie on the superior and inferior aspect of the discs adjacent to the vertebral bodies and aid in the diffusion of nutrients into the discs. As a normal part of aging, the water content of the discs decreases, leading to decreased disc height and impaired capability to absorb the axial loads of the spine. Disc herniations, annular tears, and endplate degeneration all can occur.

Location of thoracic disc herniation

Thoracic disc herniation are generally classified into 4 categories. These are central thoracic disc herniations, centrolateral thoracic disc herniations, lateral thoracic disc herniations, and intradural thoracic disc herniations. Central and centrolateral protrusions are the most common and are found in 70% of cases. Intradural herniations are rare and are found in less than 10% of cases. Clinical presentations vary, but the following generalizations are appropriate:

  • Central protrusions may cause spinal cord compression, and patients may present with myelopathic symptoms, such as increased muscle tone, hyperreflexia, abnormal gait, and urinary/bowel incontinence.
  • Centrolateral protrusions may result in a presentation resembling Brown-Sequard syndrome, with ipsilateral weakness and contralateral pain or sensory disturbances.
  • Lateral herniations may cause nerve root compression, and patients may present with a radiculopathy.

Intraosseous disc herniations

Thoracic intervertebral discs can herniate into the spinal canal as well as through vertebral endplates, directly into the adjacent vertebral bodies. The resulting herniations are called Schmorl nodes or cartilaginous nodes. These can occur in association with osteoporosis, tumors, metabolic diseases, congenital weak points in the endplates, or degenerative endplate changes. Although Schmorl nodes often do not cause symptoms, an inflammatory, foreign body–type reaction can occur, resulting in severe pain.

Scheuermann disease, or juvenile kyphosis, is a disorder of childhood in which these types of changes are particularly pronounced. Children with this disorder generally present at age 8-16 years with rigid thoracic kyphoses. Although the exact etiology is not known, endplate degeneration and avascular necrosis of the ring apophysis result in the development of multilevel Schmorl nodes and vertebral wedging. This may cause the patient to have a severe kyphotic posture and pain in the early teenage years.

Annular tears

Tears in the annulus fibrosis may contribute to thoracic discogenic pain (TDP), even in the absence of an associated disc herniation. The outer third of the annulus fibrosis is innervated by the sinuvertebral nerve, which relays sensory information, including pain, to the dorsal root ganglion. Tears in this region, particularly radial tears, may be clinically significant. A study by Schellhas et al evaluated the results of 100 patients with thoracic discographies.[5] The study found that greater than 50% of painful discs had annular tears with no evidence of significant herniation.


Calcification is also a common finding in thoracic disc herniations, particularly in those discs that are herniated as a result of degeneration. The terms “hard” disc herniations and “soft” disc herniations are used throughout the literature to indicate disc herniations with and without calcification, respectively. The presence and extent of calcification is also important in surgical planning.


Sport-Specific Biomechanics

In patients with symptomatic thoracic disc herniations for which trauma is implicated as the cause, a twisting or torsional movement is often involved. Participation in any sport that involves axial rotation of the spine can potentially increase the risk of disc herniation. These types of forces may be observed in sports such as golf, in which axial rotation of the spine is required at the top of the backswing, with subsequent uncoiling and hyperextension observed through the downswing and follow-through.

Minimizing forces on the spine through proper mechanics in specific sporting activities is important. Additionally, the dynamic stabilizers of the spine should also be strengthened to counteract the significant forces exerted on the spine during certain athletic activities.

Contributor Information and Disclosures

Gerard A Malanga, MD Founder and Partner, New Jersey Sports Medicine, LLC and New Jersey Regenerative Institute; Director of Research, Atlantic Health; Clinical Professor, Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey-New Jersey Medical School; Fellow, American College of Sports Medicine

Gerard A Malanga, MD is a member of the following medical societies: Alpha Omega Alpha, American Institute of Ultrasound in Medicine, North American Spine Society, International Spine Intervention Society, American Academy of Physical Medicine and Rehabilitation, American College of Sports Medicine

Disclosure: Received honoraria from Cephalon for speaking and teaching; Received honoraria from Endo for speaking and teaching; Received honoraria from Genzyme for speaking and teaching; Received honoraria from Prostakan for speaking and teaching; Received consulting fee from Pfizer for speaking and teaching.


Qing Tai, MD, PhD Staff Physician, Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School

Qing Tai, MD, PhD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, Academy of Spinal Cord Injury Professionals, Society for Neuroscience

Disclosure: Nothing to disclose.

Irfan Alladin, MD Staff Physician, Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School

Irfan Alladin, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Russell D White, MD Clinical Professor of Medicine, Clinical Professor of Orthopedic Surgery, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center-Lakewood

Russell D White, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Family Physicians, American Association of Clinical Endocrinologists, American College of Sports Medicine, American Diabetes Association, American Medical Society for Sports Medicine

Disclosure: Nothing to disclose.

Chief Editor

Sherwin SW Ho, MD Associate Professor, Department of Surgery, Section of Orthopedic Surgery and Rehabilitation Medicine, University of Chicago Division of the Biological Sciences, The Pritzker School of Medicine

Sherwin SW Ho, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, Arthroscopy Association of North America, Herodicus Society, American Orthopaedic Society for Sports Medicine

Disclosure: Received consulting fee from Biomet, Inc. for speaking and teaching; Received grant/research funds from Smith and Nephew for fellowship funding; Received grant/research funds from DJ Ortho for course funding; Received grant/research funds from Athletico Physical Therapy for course, research funding; Received royalty from Biomet, Inc. for consulting.

Additional Contributors

Craig C Young, MD Professor, Departments of Orthopedic Surgery and Community and Family Medicine, Medical Director of Sports Medicine, Medical College of Wisconsin

Craig C Young, MD is a member of the following medical societies: American Academy of Family Physicians, American College of Sports Medicine, American Medical Society for Sports Medicine, Phi Beta Kappa

Disclosure: Nothing to disclose.


Stephen G Andrus, MD Sports Medicine Fellow, Department of Physical Medicine and Rehabilitation, Kessler Institute for Rehabilitation, University of Medicine and Dentistry of New Jersey

Stephen G Andrus, MD is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American College of Sports Medicine, American Medical Association, and Physiatric Association of Spine, Sports and Occupational Rehabilitation

Disclosure: Nothing to disclose.

James P McLean, MD Staff Physician, Department of Physical Medicine and Rehabilitation, Kessler Institute for Rehabilitation, University of Medicine and Dentistry of New Jersey

Disclosure: Nothing to disclose.

Rachael Smith, DO Consulting Staff, Mid-Atlantic Pain Institute, PC

Rachael Smith, DO is a member of the following medical societies: American Academy of Physical Medicine and Rehabilitation, American Osteopathic Association, Association of Academic Physiatrists, and Physiatric Association of Spine, Sports and Occupational Rehabilitation

Disclosure: Nothing to disclose.

  1. Epstein NE, Epstein JA, Rosenthal AD. Thoracic disc disease. Dee R, ed. Principles of Orthopedic Practice. New York , NY: McGraw-Hill, Inc; 1989. Vol 2: 991-7.

  2. Mirkovic S, Cybulski GR. Thoracic disc herniations. Garfin SR, Vaccaro AR, eds. Orthopaedic Knowledge Update V. Rosemont, Ill: American Academy of Orthopaedic Surgeons; 1996.

  3. Awwad EE, Martin DS, Smith KR Jr, Baker BK. Asymptomatic versus symptomatic herniated thoracic discs: their frequency and characteristics as detected by computed tomography after myelography. Neurosurgery. 1991 Feb. 28(2):180-6. [Medline].

  4. Wood KB, Garvey TA, Gundry C, Heithoff KB. Magnetic resonance imaging of the thoracic spine. Evaluation of asymptomatic individuals. J Bone Joint Surg Am. 1995 Nov. 77(11):1631-8. [Medline]. [Full Text].

  5. Schellhas KP, Pollei SR, Dorwart RH. Thoracic discography. A safe and reliable technique. Spine. 1994 Sep 15. 19(18):2103-9. [Medline].

  6. Nannapaneni R, Marks SM. Posterolateral thoracic disc disease: clinical presentation and surgical experience with a modified approach. Br J Neurosurg. 2004 Oct. 18(5):467-70. [Medline].

  7. Brown CW, Deffer PA Jr, Akmakjian J, Donaldson DH, Brugman JL. The natural history of thoracic disc herniation. Spine. 1992 Jun. 17(6 suppl):S97-102. [Medline].

  8. Kaplan PA, Helms CA, Dussault R, Anderson MW, Major NM. Musculoskeletal MRI. Philadelphia, Pa: WB Saunders Company; 2001. 279-332.

  9. Wood KB, Schellhas KP, Garvey TA, Aeppli D. Thoracic discography in healthy individuals. A controlled prospective study of magnetic resonance imaging and discography in asymptomatic and symptomatic individuals. Spine. 1999 Aug 1. 24(15):1548-55. [Medline].

  10. Singh V, Manchikanti L, Onyewu O, Benyamin RM, Datta S, Geffert S, et al. An update of the appraisal of the accuracy of thoracic discography as a diagnostic test for chronic spinal pain. Pain Physician. 2012 Nov-Dec. 15(6):E757-75. [Medline].

  11. [Guideline] Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, et al. An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician. 2013 Apr. 16(2 Suppl):S49-283. [Medline].

  12. Benyamin RM, Wang VC, Vallejo R, Singh V, Helm Ii S. A systematic evaluation of thoracic interlaminar epidural injections. Pain Physician. 2012 Jul-Aug. 15(4):E497-514. [Medline].

  13. Haufe SM, Mork AR, Pyne M, Baker RA. Percutaneous laser disc decompression for thoracic disc disease: report of 10 cases. Int J Med Sci. 2010 Jun 1. 7(3):155-9. [Medline]. [Full Text].

  14. Kapural L, Sakic K, Boutwell K. Intradiscal biacuplasty (IDB) for the treatment of thoracic discogenic pain. Clin J Pain. 2010 May. 26(4):354-7. [Medline].

  15. Coppes MH, Bakker NA, Metzemaekers JD, Groen RJ. Posterior transdural discectomy: a new approach for the removal of a central thoracic disc herniation. Eur Spine J. 2011 Sep 24. [Medline].

  16. Kasliwal MK, Deutsch H. Minimally invasive retropleural approach for central thoracic disc herniation. Minim Invasive Neurosurg. 2011 Aug. 54(4):167-71. [Medline].

  17. Boswell MV, Trescot AM, Datta S, et al, for the American Society of Interventional Pain Physicians. Interventional techniques: evidence-based practice guidelines in the management of chronic spinal pain. Pain Physician. 2007 Jan. 10(1):7-111. [Medline]. [Full Text].

  18. Quint U, Bordon G, Preissl I, Sanner C, Rosenthal D. Thoracoscopic treatment for single level symptomatic thoracic disc herniation: a prospective followed cohort study in a group of 167 consecutive cases. Eur Spine J. 2011 Dec 10. [Medline].

  19. Yoshihara H, Yoneoka D. Comparison of in-hospital morbidity and mortality rates between anterior and nonanterior approach procedures for thoracic disc herniation. Spine (Phila Pa 1976). 2014 May 20. 39 (12):E728-33. [Medline].

  20. Albrand OW, Corkill G. Thoracic disc herniation. Treatment and prognosis. Spine. 1979 Jan-Feb. 4(1):41-6. [Medline].

  21. Arce CA, Dohrmann GJ. Herniated thoracic disks. Neurol Clin. 1985 May. 3(2):383-92. [Medline].

  22. Bohlman HH, Zdeblick TA. Anterior excision of herniated thoracic discs. J Bone Joint Surg Am. 1988 Aug. 70(7):1038-47. [Medline]. [Full Text].

  23. Broc GG, Crawford NR, Sonntag VK, Dickman CA. Biomechanical effects of transthoracic microdiscectomy. Spine. 1997 Mar 15. 22(6):605-12. [Medline].

  24. Carson J, Gumpert J, Jefferson A. Diagnosis and treatment of thoracic intervertebral disc protrusions. J Neurol Neurosurg Psychiatry. 1971 Feb. 34(1):68-77. [Medline]. [Full Text].

  25. Derby R, Chen Y, Lee SH, Seo KS, Kim BJ. Non-surgical interventional treatment of cervical and thoracic radiculopathies. Pain Physician. 2004 Jul. 7(3):389-94. [Medline]. [Full Text].

  26. el-Kalliny M, Tew JM Jr, van Loveren H, Dunsker S. Surgical approaches to thoracic disc herniations. Acta Neurochir (Wien). 1991. 111(1-2):22-32. [Medline].

  27. Haro H, Domoto T, Maekawa S, et al. Resorption of thoracic disc herniation. Report of 2 cases. J Neurosurg Spine. 2008 Mar. 8(3):300-4. [Medline].

  28. Hott JS, Feiz-Erfan I, Kenny K, Dickman CA. Surgical management of giant herniated thoracic discs: analysis of 20 cases. J Neurosurg Spine. 2005 Sep. 3(3):191-7. [Medline].

  29. Krauss WE, Edwards DA, Cohen-Gadol AA. Transthoracic discectomy without interbody fusion. Surg Neurol. 2005 May. 63(5):403-8; discussion 408-9. [Medline].

  30. Le Roux PD, Haglund MM, Harris AB. Thoracic disc disease: experience with the transpedicular approach in twenty consecutive patients. Neurosurgery. 1993 Jul. 33(1):58-66. [Medline].

  31. Lesoin F, Rousseaux M, Autricque A, et al. Thoracic disc herniations: evolution in the approach and indications. Acta Neurochir (Wien). 1986. 80(1-2):30-4. [Medline].

  32. Maiman DJ, Larson SJ, Luck E, El-Ghatit A. Lateral extracavitary approach to the spine for thoracic disc herniation: report of 23 cases. Neurosurgery. 1984 Feb. 14(2):178-82. [Medline].

  33. Mulier S, Debois V. Thoracic disc herniations: transthoracic, lateral, or posterolateral approach? A review. Surg Neurol. 1998 Jun. 49(6):599-606; discussion 606-8. [Medline].

  34. Ohnishi K, Miyamoto K, Kanamori Y, Kodama H, Hosoe H, Shimizu K. Anterior decompression and fusion for multiple thoracic disc herniation. J Bone Joint Surg Br. 2005 Mar. 87(3):356-60. [Medline]. [Full Text].

  35. Patterson RH Jr, Arbit E. A surgical approach through the pedicle to protruded thoracic discs. J Neurosurg. 1978 May. 48(5):768-72. [Medline].

  36. Perez-Cruet MJ, Kim BS, Sandhu F, Samartzis D, Fessler RG. Thoracic microendoscopic discectomy. J Neurosurg Spine. 2004 Jul. 1(1):58-63. [Medline].

  37. Perot PL Jr, Munro DD. Transthoracic removal of midline thoracic disc protrusions causing spinal cord compression. J Neurosurg. 1969 Oct. 31(4):452-8. [Medline].

  38. Ransohoff J, Spencer F, Siew F, Gage L Jr. Transthoracic removal of thoracic disc. Report of three cases. J Neurosurg. 1969 Oct. 31(4):459-61. [Medline].

  39. Regan JJ, Ben-Yishay A, Mack MJ. Video-assisted thoracoscopic excision of herniated thoracic disc: description of technique and preliminary experience in the first 29 cases. J Spinal Disord. 1998 Jun. 11(3):183-91. [Medline].

  40. Rosenthal D, Rosenthal R, de Simone A. Removal of a protruded thoracic disc using microsurgical endoscopy. A new technique. Spine. 1994 May 1. 19(9):1087-91. [Medline].

  41. Simpson JM, Silveri CP, Simeone FA, Balderston RA, An HS. Thoracic disc herniation. Re-evaluation of the posterior approach using a modified costotransversectomy. Spine. 1993 Oct 1. 18(13):1872-7. [Medline].

  42. Stillerman CB, Chen TC, Couldwell WT, Zhang W, Weiss MH. Experience in the surgical management of 82 symptomatic herniated thoracic discs and review of the literature. J Neurosurg. 1998 Apr. 88(4):623-33. [Medline].

  43. Stillerman CB, Weiss MH. Management of thoracic disc disease. Clin Neurosurg. 1992. 38:325-52. [Medline].

  44. Ulivieri S, Oliveri G, Petrini C, Voltolini L, Gotti G. Transmanubrial osteomuscolar sparing approach for T1-T2 thoracic disc herniation. Minerva Chir. 2008 Oct. 63(5):421-3. [Medline].

  45. Wakefield AE, Steinmetz MP, Benzel EC. Biomechanics of thoracic discectomy. Neurosurg Focus. 2001 Sep 15. 11(3):E6. [Medline].

  46. Wenger DR, Frick SL. Scheuermann kyphosis. Spine. 1999 Dec 15. 24(24):2630-9. [Medline].

  47. Williams MP, Cherryman GR, Husband JE. Significance of thoracic disc herniation demonstrated by MR imaging. J Comput Assist Tomogr. 1989 Mar-Apr. 13(2):211-4. [Medline].

  48. Wood KB, Blair JM, Aepple DM, et al. The natural history of asymptomatic thoracic disc herniations. Spine. 1997 Mar 1. 22(5):525-9; discussion 529-30. [Medline].

Axial magnetic resonance image of a thoracic herniated disc.
Sagittal magnetic resonance image of a lower thoracic herniated disc.
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