Bicipital Tendonitis Medication
- Author: Britt A Durham, MD; Chief Editor: Sherwin SW Ho, MD more...
The goals of pharmacotherapy are to reduce patient morbidity and prevent complications.
Nonsteroidal anti-inflammatory drugs (NSAIDs)
NSAIDs are anti-inflammatory and non-narcotic medications that have analgesic and antipyretic activities. The mechanism of action of these agents is not known, but NSAIDs may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions. The treatment of pain tends to be patient specific.
DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.
Local anesthetics block the generation of conduction impulses in a nerve, thereby preventing the transmission of pain.
An amide-type local anesthetic that shares similar properties with other drugs in this classification, including lidocaine (Xylocaine; AstraZeneca, Mississauga, Ontario, Canada). Has the advantage of a longer duration of anesthesia.
Administer the smallest dose and concentration that is required to produce the desired results. Dose varies with the anesthetic procedure, the area to be anesthetized, the vascularity of the tissues, and individual tolerance.
Glucocorticoids stimulate synthesis of enzymes that decrease inflammatory responses and suppress the immune system.
Methylprednisolone is a potent, intermediate-acting glucocorticoid, which has no mineralocorticoid activity. A useful anti-inflammatory and immunosuppressant agent.
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