eMedicine Specialties > Pediatrics: General Medicine > Infectious Disease

Lymphangitis: Follow-up

Author: Raymond D Pitetti, MD, MPH, Associate Professor, Department of Pediatrics, Division of Pediatric Emergency Medicine, University of Pittsburgh School of Medicine; Consulting Staff, University of Pittsburgh Physicians
Contributor Information and Disclosures

Updated: May 22, 2009

Follow-up

Further Inpatient Care

  • Some patients with lymphangitis may require admission for intravenous (IV) antimicrobial therapy.
  • Most authors recommend that children younger than 3 years or children who are febrile and who appear toxic initially be treated with IV antibiotics.
  • Children who have not improved clinically after 48 hours of appropriate PO antimicrobial therapy should receive IV antistaphylococcal and antistreptococcal therapy.
  • When erythema, warmth, and edema are markedly reduced, antibiotics can be changed to the oral (PO) route.

Complications

  • Lymphangitis may spread within hours.
  • Bacteremia and sepsis can occur.
  • Without appropriate antimicrobial therapy, cellulitis may develop or extend along the channels; necrosis and ulceration may occur.
  • Lymphangitis caused by group A beta-hemolytic streptococcus (GABHS) can progress rapidly, leading to bacteremia, sepsis, and death.
  • Guidelines to prevent transmission of methicillin-resistant S aureus have been established.4

Prognosis

  • The prognosis for patients with uncomplicated lymphangitis is good.
  • Antimicrobial regimens are effective in more than 90% of cases.

Patient Education

Miscellaneous

Medicolegal Pitfalls

  • Failure to provide timely and appropriate antimicrobial therapy may lead to cellulitis, abscess formation, bacteremia, and sepsis.
 


More on Lymphangitis

Overview: Lymphangitis
Differential Diagnoses & Workup: Lymphangitis
Treatment & Medication: Lymphangitis
Follow-up: Lymphangitis
Multimedia: Lymphangitis
References

References

  1. Abraham S, Tschanz C, Krischer J, Saurat JH. Lymphangitis due to insect sting. Dermatology. 2007;215(3):260-1. [Medline].

  2. Marque M, Girard C, Guillot B, Bessis D. Superficial lymphangitis after arthropod bite: a distinctive but underrecognized entity?. Dermatology. 2008;217(3):262-7. [Medline].

  3. Hirschmann JV. Antimicrobial therapy for skin infections. Cutis. Jun 2007;79(6 Suppl):26-36. [Medline].

  4. [Guideline] Calfee DP, Salgado CD, Classen D, et al. Strategies to prevent transmission of methicillin-resistant Staphylococcus aureus in acute care hospitals. Infect Control Hosp Epidemiol. Oct 2008;29 Suppl 1:S62-80. [Medline].

  5. Addiss DG, Eberhard ML, Lammie PJ. "Filarial" adenolymphangitis without filarial infection. Lancet. Mar 5 1994;343(8897):597. [Medline].

  6. Ben-Amitai D, Ashkenazi S. Common bacterial skin infections in childhood. Pediatr Ann. Apr 1993;22(4):225-7, 231-3. [Medline].

  7. Brook I. Management of human and animal bite wounds: an overview. Adv Skin Wound Care. May 2005;18(4):197-203. [Medline].

  8. Brook I. Microbiology and management of human and animal bite wound infections. Prim Care. Mar 2003;30(1):25-39, v. [Medline].

  9. Brown G, Chamberlain R, Goulding J, Clarke A. Ceftriaxone versus cefazolin with probenecid for severe skin and soft tissue infections. J Emerg Med. Sep-Oct 1996;14(5):547-51. [Medline].

  10. Ellis Simonsen SM, van Orman ER, Hatch BE, et al. Cellulitis incidence in a defined population. Epidemiol Infect. Apr 2006;134(2):293-9. [Medline].

  11. Falagas ME, Bliziotis IA, Kapaskelis AM. Red streaks on the leg. Lymphangitis. Am Fam Physician. Mar 15 2006;73(6):1061-2. [Medline].

  12. Fleisher G, Ludwig S, Campos J. Cellulitis: bacterial etiology, clinical features, and laboratory findings. J Pediatr. Oct 1980;97(4):591-3. [Medline].

  13. Hacker SM. Common infections of the skin. Characteristics, causes, and cures. Postgrad Med. Aug 1994;96(2):43-6, 49-52. [Medline].

  14. Howe PM, Eduardo Fajardo J, Orcutt MA. Etiologic diagnosis of cellulitis: comparison of aspirates obtained from the leading edge and the point of maximal inflammation. Pediatr Infect Dis J. Jul 1987;6(7):685-6. [Medline].

  15. Jain A, Daum RS. Staphylococcal infections in children: Part 1. Pediatr Rev. Jun 1999;20(6):183-91. [Medline].

  16. Jungmann P, Figueredo-Silva J, Dreyer G. Bancroftian lymphangitis in northeastern Brazil: a histopathological study of 17 cases. J Trop Med Hyg. Apr 1992;95(2):114-8. [Medline].

  17. Kazura JW, Spark R, Forsyth K, et al. Parasitologic and clinical features of bancroftian filariasis in a community in East Sepik Province, Papua New Guinea. Am J Trop Med Hyg. Nov 1984;33(6):1119-23. [Medline].

  18. Kostman JR, DiNubile MJ. Nodular lymphangitis: a distinctive but often unrecognized syndrome. Ann Intern Med. Jun 1 1993;118(11):883-8. [Medline].

  19. Sadick NS. Current aspects of bacterial infections of the skin. Dermatol Clin. Apr 1997;15(2):341-9. [Medline].

  20. Santos JI, Jacobson JA, Swensen P, Palmer WM. Cellulitis: treatment with cefoxitin compared with multiple antibiotic therapy. Pediatrics. Jun 1981;67(6):887-90. [Medline].

  21. Schwartz R, Das-Young LR, Ramirez-Ronda C, Frank E. Current and future management of serious skin and skin-structure infections. Am J Med. Jun 24 1996;100(6A):90S-95S. [Medline].

  22. Sigurdsson AF, Gudmundsson S. The etiology of bacterial cellulitis as determined by fine-needle aspiration. Scand J Infect Dis. 1989;21(5):537-42. [Medline].

  23. Yagupsky P. Bacteriologic aspects of skin and soft tissue infections. Pediatr Ann. Apr 1993;22(4):217-24. [Medline].

Further Reading

Keywords

lymphangitis, lymphangeitis, lymphangiitis, lymphatic system, inflammation of the lymphatic channels, bacteremia, cellulitis, septic thrombophlebitis, superficial thrombophlebitis, necrotizing fasciitis, myositis, sporotrichosis, Staphylococcus aureus, Pseudomonas, Streptococcus pneumoniae, Pasteurella multocida, Aermonas hydrophila, treatment, diagnosis

Contributor Information and Disclosures

Author

Raymond D Pitetti, MD, MPH, Associate Professor, Department of Pediatrics, Division of Pediatric Emergency Medicine, University of Pittsburgh School of Medicine; Consulting Staff, University of Pittsburgh Physicians
Raymond D Pitetti, MD, MPH is a member of the following medical societies: Allegheny County Medical Society, American Academy of Pediatrics, Pennsylvania Medical Society, and Society for Pediatric Research
Disclosure: Nothing to disclose.

Medical Editor

Gary J Noel, MD, Department of Pediatrics, Clinical Associate Professor, Weill Medical College of Cornell University
Gary J Noel, MD is a member of the following medical societies: Pediatric Infectious Diseases Society
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Larry I Lutwick, MD, Professor of Medicine, State University of New York, Downstate Medical School; Director, Infectious Diseases, Veterans Affairs New York Harbor Health Care System, Brooklyn Campus
Larry I Lutwick, MD is a member of the following medical societies: American College of Physicians and Infectious Diseases Society of America
Disclosure: Nothing to disclose.

CME Editor

Robert W Tolan Jr, MD, Chief, Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital; Clinical Associate Professor of Pediatrics, Drexel University College of Medicine
Robert W Tolan Jr, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Phi Beta Kappa, and Physicians for Social Responsibility
Disclosure: GlaxoSmithKline Honoraria Speaking and teaching; MedImmune Honoraria Speaking and teaching; Merck Honoraria Speaking and teaching; sanofi pasteur Honoraria Speaking and teaching; Baxter Healthcare Honoraria Speaking and teaching

Chief Editor

Russell W Steele, MD, Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine
Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association
Disclosure: None None None

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.