Mumps Medication

  • Author: Germaine L Defendi, MD, MS, FAAP; Chief Editor: Russell W Steele, MD   more...
 
Updated: Feb 6, 2012
 

Medication Summary

Treatment of mumps is usually supportive care. Vaccine pharmacotherapy is used to immunize the child.

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Analgesics

Class Summary

These agents may be prescribed for severe headaches or discomfort due to parotitis. In orchitis, stronger analgesics may be needed.

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Ibuprofen (Advil, Motrin, NeoProfen)

 

This is the drug of choice for patients with mild to moderate pain and fever. It inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

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Acetaminophen (Tylenol, Aspirin Free Anacin, FeverAll)

 

This is the drug of choice for pain in patients with documented hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs), with upper GI disease, or who are taking PO anticoagulants. Acetaminophen reduces fever by acting directly on hypothalamic heat-regulating centers, which increases dissipation of body heat via vasodilation and sweating.

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Vaccines (measles, mumps, rubella)

Class Summary

Prevention of mumps through immunization cannot be overemphasized. All children younger than 7 years should receive the mumps vaccine. In the United States, mumps vaccine is recommended and is usually combined with MMR.

The combined measles-mumps-rubella-varicella (MMRV) vaccine (ProQuad) has been shown to be associated with an increased risk of febrile seizure occurring 5-12 days following vaccination at a rate of 1 in 2300-2600, in children aged 12 -23 months, compared with separate MMR vaccine and varicella vaccine administered simultaneously.[27, 28] As a result, the CDC Advisory Committee on Immunization Practices (ACIP) recommends that separate MMR and varicella vaccines be used for the first dose, although providers or parents may opt to use the combined MMRV vaccine for the first dose after counseling regarding this risk.[29] MMRV is preferred for the second dose (at any age) or for the first dose if given at age 48 months or older.

Data from postlicensure studies did not suggest that children aged 4-6 years who received the second dose of MMRV vaccine had an increased risk for febrile seizures after vaccination compared with children the same age who received MMR vaccine and varicella vaccine administered as separate injections at the same visit.[29]

Measles-mumps-rubella vaccine, live (MMR)

 

Live virus vaccine. Combined MMR vaccine is recommended for the prevention of mumps, measles, and rubella. For children, the typical recommended 2-dose schedule is administered at age 12-15 months for the 1st dose and age 4-6 years for the second dose.

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Contributor Information and Disclosures
Author

Germaine L Defendi, MD, MS, FAAP  Associate Clinical Professor, Department of Pediatrics, Olive View-UCLA Medical Center

Germaine L Defendi, MD, MS, FAAP is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Coauthor(s)

Cem S Demirci, MD  Consulting Staff, Division of Endocrinology/Diabetes, Connecticut Children's Medical Center

Disclosure: Nothing to disclose.

Walid Abuhammour, MD, FAAP  Professor of Pediatrics, Michigan State University College of Medicine; Director of Pediatric Infectious Disease, Department of Pediatrics, Hurley Medical Center

Walid Abuhammour, MD, FAAP is a member of the following medical societies: American Medical Association, Infectious Diseases Society of America, and Pediatric Infectious Diseases Society

Disclosure: Nothing to disclose.

Chief Editor

Russell W Steele, MD  Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine

Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association

Disclosure: Nothing to disclose.

Additional Contributors

Gary J Noel, MD Professor, Department of Pediatrics, Weill Cornell Medical College; Attending Pediatrician, New York-Presbyterian Hospital

Gary J Noel, MD is a member of the following medical societies: Pediatric Infectious Diseases Society

Disclosure: Nothing to disclose.

Eileen C Quintana MD, Assistant Professor, Departments of Pediatrics and Emergency Medicine, St Christopher's Hospital for Children; Adjunct Clinical Professor, Pediatrics and Emergency Medicine Departments, Temple University Hospital, Pediatric Emergency Dept, Philadelphia, PA

Eileen C Quintana is a member of the following medical societies: American College of Emergency Physicians and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Mark R Schleiss, MD American Legion Chair of Pediatrics, Professor of Pediatrics, Division Director, Division of Infectious Diseases and Immunology, Department of Pediatrics, University of Minnesota Medical School

Mark R Schleiss, MD is a member of the following medical societies: American Pediatric Society, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Hosseinali Shahidi, MD, MPH Assistant Professor, Departments of Emergency Medicine and Pediatrics, State University of New York and Health Science Center at Brooklyn

Hosseinali Shahidi, MD, MPH is a member of the following medical societies: American Academy of Pediatrics, American College of Emergency Physicians, and American Public Health Association

Disclosure: Nothing to disclose.

Garry Wilkes MBBS, FACEM, Director of Emergency Medicine, Calvary Hospital, Canberra, ACT; Adjunct Associate Professor, Edith Cowan University; Clinical Associate Professor, Rural Clinical School, University of Western Australia

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Grace M Young, MD Associate Professor, Department of Pediatrics, University of Maryland Medical Center

Grace M Young, MD is a member of the following medical societies: American Academy of Pediatrics and American College of Emergency Physicians

Disclosure: Nothing to disclose.

References

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  20. Niizuma T, Terada K, Kosaka Y, Daimon Y, Inoue M, Ogita S, et al. Elevated serum C-reactive protein in mumps orchitis. Pediatr Infect Dis J. Oct 2004;23(10):971. [Medline].

  21. Deeks SL, Lim GH, Simpson MA, et al. An assessment of mumps vaccine effectiveness by dose during an outbreak in Canada. CMAJ. Jun 14 2011;183(9):1014-20. [Medline]. [Full Text].

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  27. Klein NP, Fireman B, Yih WK, Lewis E, Kulldorff M, Ray P, et al. Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures. Pediatrics. Jul 2010;126(1):e1-8. [Medline].

  28. Hviid A. Measles-mumps-rubella-varicella combination vaccine increases risk of febrile seizure. J Pediatr. Jan 2011;158(1):170. [Medline]. [Full Text].

  29. [Guideline] Marin M, Broder KR, Temte JL, Snider DE, Seward JF. Use of combination measles, mumps, rubella, and varicella vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. May 7 2010;59:1-12. [Medline]. [Full Text].

 
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