Pediatric Escherichia Coli Infections Differential Diagnoses

  • Author: Archana Chatterjee, MD, PhD; Chief Editor: Russell W Steele, MD   more...
 
Updated: Nov 9, 2011
 
 

Differential Diagnoses

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Contributor Information and Disclosures
Author

Archana Chatterjee, MD, PhD  Professor of Pediatrics, Medical Microbiology and Immunology, and Pharmacy, Division of Pediatric Infectious Diseases, Chief of Division of Pediatric Infectious Diseases, Creighton University School of Medicine; Hospital Epidemiologist and Medical Director of Infection Control, Children's Hospital

Archana Chatterjee, MD, PhD is a member of the following medical societies: American Academy of Pediatrics, American Society for Microbiology, International Society for Infectious Diseases, Pediatric Infectious Diseases Society, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Coauthor(s)

Catherine O'Keefe, DNP, APRN  Assistant Professor of Nursing and Pediatric Nurse Practitioner, Pediatric Infectious Diseases, Creighton University Medical Center

Catherine O'Keefe, DNP, APRN is a member of the following medical societies: American Academy of Nurse Practitioners, National Association of Pediatric Nurse Practitioners, and Nebraska Nurse Practitioners

Disclosure: Nothing to disclose.

Sara L Cuthill, MD  Fellow, Developmental and Behavioral Pediatrics, Departmental and Behavioral Pediatrics, Interstate Medical Office East

Sara L Cuthill, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Meera Varman, MD  Associate Professor, Department of Pediatrics, Section of Pediatric Infectious Diseases, Creighton University Medical Center

Meera Varman, MD is a member of the following medical societies: American Academy of Pediatrics, Infectious Diseases Society of America, and Pediatric Infectious Diseases Society

Disclosure: phamaceutical companies Honoraria Speaking and teaching; phamaceutical companies Grant/research funds clinical trials

Specialty Editor Board

Ashir Kumar, MD, MBBS, FAAP  Professor Emeritus, Department of Pediatrics and Human Development, Michigan State University College of Human Medicine

Ashir Kumar, MD, MBBS, FAAP is a member of the following medical societies: American Association of Physicians of Indian Origin and Infectious Diseases Society of America

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Mark R Schleiss, MD  American Legion Chair of Pediatrics, Professor of Pediatrics, Division Director, Division of Infectious Diseases and Immunology, Department of Pediatrics, University of Minnesota Medical School

Mark R Schleiss, MD is a member of the following medical societies: American Pediatric Society, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Robert W Tolan Jr, MD  Chief, Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital; Clinical Associate Professor of Pediatrics, Drexel University College of Medicine

Robert W Tolan Jr, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, American Society for Microbiology, American Society of Tropical Medicine and Hygiene, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Phi Beta Kappa, and Physicians for Social Responsibility

Disclosure: Novartis Honoraria Speaking and teaching

Chief Editor

Russell W Steele, MD  Head, Division of Pediatric Infectious Diseases, Ochsner Children's Health Center; Clinical Professor, Department of Pediatrics, Tulane University School of Medicine

Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, and Southern Medical Association

Disclosure: Nothing to disclose.

References

  1. Nataro JP. Escherichia coli. In: Long S, Pickering LK, Prober CG (Editors). Principles and Practice of Pediatric Infectious Diseases. 3rd Edition. Orlando, Fl: Churchill Livingstone; 2008.

  2. Escherichia coli diarrhea. In: Pickering LK, Baker CJ, Overturf GD, Prober CG (Editors). American Academy of Pediatricians Report of the Committee on Infectious Diseases. Red Book. 2008:291-6.

  3. Centers for Disease Control and Prevention. Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food--10 states, 2007. MMWR Morb Mortal Wkly Rep. Apr 11 2008;57(14):366-70. [Medline].

  4. WHO. Enterotoxigenic escherichia coli. World Health Organization. Available at http://www.who.int/vaccine_research/diseases/e_e_coli/en/. Accessed 10/01/2008.

  5. Gupta SK, Keck J, Ram PK, Crump JA, Miller MA, Mintz ED. Part III. Analysis of data gaps pertaining to enterotoxigenic Escherichia coli infections in low and medium human development index countries, 1984-2005. Epidemiol Infect. Jun 2008;136(6):721-38. [Medline].

  6. Qadri F, Svennerholm AM, Faruque AS, et al. Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention. Clin Microbiol Rev. Jul 2005;18(3):465-83. [Medline].

  7. Bolin I, Wiklund G, Qadri F, et al. Enterotoxigenic Escherichia coli with STh and STp genotypes is associated with diarrhea both in children in areas of endemicity and in travelers. J Clin Microbiol. Nov 2006;44(11):3872-7. [Medline].

  8. Rockabrand DM, Shaheen HI, Khalil SB, et al. Enterotoxigenic Escherichia coli colonization factor types collected from 1997 to 2001 in US military personnel during operation Bright Star in northern Egypt. Diagn Microbiol Infect Dis. May 2006;55(1):9-12. [Medline].

  9. Buchholz U, Bernard H, Werber D, et al. German Outbreak of Escherichia coli O104:H4 Associated with Sprouts. N Engl J Med. Oct 26 2011;[Medline].

  10. Frank C, Werber D, Cramer JP, et al. Epidemic Profile of Shiga-Toxin-Producing Escherichia coli O104:H4 Outbreak in Germany. N Engl J Med. Jun 22 2011;[Medline].

  11. Centers for Disease Control and Prevention. Escherichia coli O157:H7 infection associated with drinking raw milk--Washington and Oregon, November-December 2005. MMWR Morb Mortal Wkly Rep. Mar 2 2007;56(8):165-7. [Medline].

  12. Rossit AR, de Almeida MT, Nogueira CA, et al. Bacterial, yeast, parasitic, and viral enteropathogens in HIV-infected children from São Paulo State, Southeastern Brazil. Diagn Microbiol Infect Dis. Jan 2007;57(1):59-66. [Medline].

  13. Gassama A, Sow PS, Fall F, et al. Ordinary and opportunistic enteropathogens associated with diarrhea in Senegalese adults in relation to human immunodeficiency virus serostatus. Int J Infect Dis. 2001;5(4):192-8. [Medline].

  14. Hien BT, Scheutz F, Cam PD, et al. Diarrheagenic Escherichia coli and Shigella strains isolated from children in a hospital case-control study in Hanoi, Vietnam. J Clin Microbiol. Mar 2008;46(3):996-1004. [Medline].

  15. Al-Gallas N, Bahri O, Bouratbeen A, et al. Etiology of acute diarrhea in children and adults in Tunis, Tunisia, with emphasis on diarrheagenic Escherichia coli: prevalence, phenotyping, and molecular epidemiology. Am J Trop Med Hyg. Sep 2007;77(3):571-82. [Medline].

  16. Centers for Disease Control and Prevention. Escherichia coli 0157:H7 infections in children associated with raw milk and raw colostrum from cows--California, 2006. MMWR Morb Mortal Wkly Rep. Jun 13 2008;57(23):625-8. [Medline].

  17. Centers for Disease Control and Prevention. Ongoing multistate outbreak of Escherichia coli serotype O157:H7 infections associated with consumption of fresh spinach--United States, September 2006. MMWR Morb Mortal Wkly Rep. Sep 29 2006;55(38):1045-6. [Medline].

  18. Diarrheagenic Escherichia coli. Centers for Disease Control and Prevention. Available at http://www.cdc.gov/ncidod/dbmd/diseaseinfo/diarrecoli_t.htm. Accessed October 1, 2008.

  19. Serna A 4th, Boedeker EC. Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections. Curr Opin Gastroenterol. Jan 2008;24(1):38-47. [Medline].

  20. Zhang W, Bielaszewska M, Pulz M, et al. New immuno-PCR assay for detection of low concentrations of shiga toxin 2 and its variants. J Clin Microbiol. Apr 2008;46(4):1292-7. [Medline].

  21. Beutin L, Steinruck H, Krause G, et al. Comparative evaluation of the Ridascreen Verotoxin enzyme immunoassay for detection of Shiga-toxin producing strains of Escherichia coli (STEC) from food and other sources. J Appl Microbiol. Mar 2007;102(3):630-9. [Medline].

  22. Lothigius A, Janzon A, Begum Y, et al. Enterotoxigenic Escherichia coli is detectable in water samples from an endemic area by real-time PCR. J Appl Microbiol. Apr 2008;104(4):1128-36. [Medline].

  23. Morgan J, Bell M, Sadler MA. CT imaging of acute E. Coli-related colitis. Emerg Radiol. Jul 2007;14(3):187-9. [Medline].

  24. Kliegman RM, Behrman RE, Jenson HB, et al. The pathophysiology of body fluids and fluid therapy. In: Nelson Textbook of Pediatrics, 18th ed. Elsevier Health Sciences,. 2007:Ch. 55.1.

  25. Wong CS, Jelacic S, Habeeb RL, et al. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med. Jun 29 2000;342(26):1930-6. [Medline].

  26. Scheiring J, Andreoli SP, Zimmerhackl LB. Treatment and outcome of Shiga-toxin-associated hemolytic uremic syndrome (HUS). Pediatr Nephrol. Oct 2008;23(10):1749-60. [Medline].

  27. Safdar N, Said A, Gangnon RE, Maki DG. Risk of hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 enteritis: a meta-analysis. JAMA. Aug 28 2002;288(8):996-1001. [Medline].

  28. Ake JA, Jelacic S, Ciol MA, et al. Relative nephroprotection during Escherichia coli O157:H7 infections: association with intravenous volume expansion. Pediatrics. Jun 2005;115(6):e673-80. [Medline].

  29. Anjay MA, Anoop P, Britland A. Leukocytosis as a predictor for progression to haemolytic uraemic syndrome in Escherichia coli O157:H7 infection. Arch Dis Child. Sep 2007;92(9):820-3. [Medline].

  30. Joishy M, Jauhari P, Mathew AA, et al. Can we predict the development of haemolytic uraemic syndrome in the early stage of Escherichia coli O157 infection?. Arch Dis Child. Feb 2008;93(2):180-1. [Medline].

  31. Saps M, Pensabene L, Di Martino L, et al. Post-infectious functional gastrointestinal disorders in children. J Pediatr. Jun 2008;152(6):812-6, 816.e1. [Medline].

  32. [Best Evidence] Frech SA, Dupont HL, Bourgeois AL, et al. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet. Jun 14 2008;371(9629):2019-25. [Medline].

  33. Glenn GM, Villar CP, Flyer DC, et al. Safety and immunogenicity of an enterotoxigenic Escherichia coli vaccine patch containing heat-labile toxin: use of skin pretreatment to disrupt the stratum corneum. Infect Immun. May 2007;75(5):2163-70. [Medline].

  34. Ahmed A, Li J, Shiloach Y, et al. Safety and immunogenicity of Escherichia coli O157 O-specific polysaccharide conjugate vaccine in 2-5-year-old children. J Infect Dis. Feb 15 2006;193(4):515-21. [Medline].

  35. Amieva MR. Important bacterial gastrointestinal pathogens in children: a pathogenesis perspective. Pediatr Clin North Am. Jun 2005;52(3):749-77, vi. [Medline].

  36. Blackall DP, Marques MB. Hemolytic uremic syndrome revisited: Shiga toxin, factor H, and fibrin generation. Am J Clin Pathol. Jun 2004;121 Suppl:S81-8. [Medline].

  37. David RD, DeBlieux PM, Press R. Rational antibiotic treatment of outpatient genitourinary infections in a changing environment. Am J Med. Jul 2005;118 Suppl 7A:7S-13S. [Medline].

  38. Investigation of multistate outbreak of E. coli O157:H7 infections: Updated July 18, 2008. Centers for Disease Control and Prevention. Available at http://www.cdc.gov/ecoli/june2008outbreak/. Accessed September 30, 2008.

  39. Li F, Zhao C, Zhang W, et al. Use of ramification amplification assay for detection of Escherichia coli O157:H7 and other E. coli Shiga toxin-producing strains. J Clin Microbiol. Dec 2005;43(12):6086-90. [Medline]. [Full Text].

  40. Mehnert-Kay SA. Diagnosis and management of uncomplicated urinary tract infections. Am Fam Physician. Aug 1 2005;72(3):451-6. [Medline].

  41. Stoll BJ, Hansen N. Infections in VLBW infants: studies from the NICHD Neonatal Research Network. Semin Perinatol. Aug 2003;27(4):293-301. [Medline].

  42. Tarr PI, Gordon CA, Chandler WL. Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet. Mar 19-25 2005;365(9464):1073-86. [Medline].

  43. Vidal M, Kruger E, Duran C, et al. Single multiplex PCR assay to identify simultaneously the six categories of diarrheagenic Escherichia coli associated with enteric infections. J Clin Microbiol. Oct 2005;43(10):5362-5. [Medline]. [Full Text].

  44. Yates J. Traveler's diarrhea. Am Fam Physician. Jun 1 2005;71(11):2095-100. [Medline].

 
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