Medication Summary
Oral NSAIDs can be helpful to reduce the pain and inflammation of olecranon bursitis, but these products probably should be avoided if joint aspiration reveals a hemorrhagic bursitis. Injectable corticosteroid can be beneficial in cases in which the history, physical examination, and joint aspiration do not raise a significant suspicion for infection. Various oral NSAIDs can be used, but none holds a clear distinction as the drug of choice (DOC).
Empiric antibiotic selection is based upon the suspected source of the microorganisms (skin flora with local invasion via puncture or abrasion vs hematogenous spread from a primary infection at another body site). Antibiotic selection is further modified by the results of the culture and sensitivity. Initial antibiotic selection would also be directed by the result of the Gram stain of the aspirate. Antibiotic treatment may start with a broad-spectrum antibiotic; then, when the culture results are available, the antibiotic regimen may be modified as appropriate.
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Class Summary
NSAIDs can help decrease pain and inflammation. Various oral NSAIDs can be used, but none holds a clear distinction as the DOC. Choice of NSAID is largely a matter of convenience (eg, how frequently doses must be taken to achieve adequate analgesic and anti-inflammatory effects) and cost.
Ibuprofen (Motrin, Advil, Nuprin, NeoProfen)
Commonly used NSAID. Many doses are available, either with or without a prescription.
Ketoprofen (Actron, Orudis, Oruvail)
For the relief of mild to moderate pain and inflammation. Small dosages are initially indicated in small and elderly patients and in those with renal or liver disease. Doses over 75 mg do not increase therapeutic effects. Administer high doses with caution, and closely observe the patient for response.
Corticosteroid Preparation for Focal Injection
Class Summary
In contrast to the widespread systemic distribution of an oral anti-inflammatory drug, a local corticosteroid injection can achieve focal placement of a potent anti-inflammatory agent at the site of maximal tenderness or inflammation.[1, 3, 11, 12, 15]
When corticosteroid injections are used, a variety of corticosteroid preparations are available to choose from. Commonly, the corticosteroid is mixed with a local anesthetic agent before administering the injection. Again, there are various local anesthetic agents to choose from.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol, Kenalog)
Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability. Commonly used for injections into bursae or joints.
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