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Hamate Fracture Medication

  • Author: Amy Powell, MD; Chief Editor: Sherwin SW Ho, MD  more...
Updated: Oct 13, 2015

Medication Summary

Pain control following surgery is the most common medication concern. Usually, 5-7 days of a low-strength narcotic analgesic, followed by over-the-counter (OTC) nonsteroidal anti-inflammatory drugs (NSAIDs), is sufficient to control pain in most patients. Sufficient amounts of pain medication should be used in the early phases of physical therapy to allow maximum movement with minimal discomfort. Pain control encourages the patient to continue in the program and speeds recovery of the wrist.

Antibiotic coverage has proven to have little value in the full spectrum of hand injuries; however, its use in open fractures is of definite value.[26, 27] Although only a short course, 1-5 days of cephalosporin therapy must be administered. The speed of administration is of primary concern. Continued therapy more than 48 hours after definitive wound closure has been achieved is not necessary. No antibiotic therapy can compensate for a lack of adequate debridement.[28]



Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma.

Related Medscape resources:

Resource CenterPain Management: Advanced Approaches to Chronic Pain Management

Resource CenterPain Management: Pharmacologic Approaches

Hydrocodone/Acetaminophen (Lortab, Vicodin, Norcet),


Indicated for moderate to severe pain.


Nonsteroidal anti-inflammatory drugs

Class Summary

Although most NSAIDs are used primarily for their anti-inflammatory effects, they are effective analgesics and are useful for mild to moderate pain.

Related Medscape Reference topic:

Nonsteroidal Anti-inflammatory Agent Toxicity

Ibuprofen (Motrin, Ibuprin)


DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.



Class Summary

Antibiotic therapy must be comprehensive and cover all likely pathogens in the context of this clinical setting.

Related Medscape resource:

Resource CenterSepsis: Pathophysiology and Treatment

Cefazolin sodium (Ancef, Kefzol, Zolicef)


First-generation cephalosporin. Bactericidal, binds to bacterial membranes, and inhibits cell wall synthesis. Has a half-life of 1.4-1.8 h, which is increased in the presence of renal dysfunction. Excreted primarily unchanged in urine.

Contributor Information and Disclosures

Amy Powell, MD Assistant Clinical Professor, Department of Orthopedics, University of Utah

Amy Powell, MD is a member of the following medical societies: American College of Physicians, American College of Sports Medicine, American Medical Society for Sports Medicine

Disclosure: Nothing to disclose.


Janos P Ertl, MD Assistant Professor, Department of Orthopedic Surgery, Indiana University School of Medicine; Chief of Orthopedic Surgery, Wishard Hospital; Chief, Sports Medicine and Arthroscopy, Indiana University School of Medicine

Janos P Ertl, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Orthopaedic Association, Hungarian Medical Association of America, Sierra Sacramento Valley Medical Society

Disclosure: Nothing to disclose.

Nancy J Taubenheim, DPT Staff Physical Therapist, Clinical Instructor, Department of Rehabilitation Services, Bryan LGH Medical Center

Disclosure: Nothing to disclose.

Warren S Theis, MD Staff Physician, Department of General Surgery, Carilion Roanoke Memorial Hospital

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Henry T Goitz, MD Academic Chair and Associate Director, Detroit Medical Center Sports Medicine Institute; Director, Education, Research, and Injury Prevention Center; Co-Director, Orthopaedic Sports Medicine Fellowship

Henry T Goitz, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Orthopaedic Society for Sports Medicine

Disclosure: Nothing to disclose.

Chief Editor

Sherwin SW Ho, MD Associate Professor, Department of Surgery, Section of Orthopedic Surgery and Rehabilitation Medicine, University of Chicago Division of the Biological Sciences, The Pritzker School of Medicine

Sherwin SW Ho, MD is a member of the following medical societies: American Academy of Orthopaedic Surgeons, Arthroscopy Association of North America, Herodicus Society, American Orthopaedic Society for Sports Medicine

Disclosure: Received consulting fee from Biomet, Inc. for speaking and teaching; Received grant/research funds from Smith and Nephew for fellowship funding; Received grant/research funds from DJ Ortho for course funding; Received grant/research funds from Athletico Physical Therapy for course, research funding; Received royalty from Biomet, Inc. for consulting.

Additional Contributors

Gerard A Malanga, MD Founder and Partner, New Jersey Sports Medicine, LLC and New Jersey Regenerative Institute; Director of Research, Atlantic Health; Clinical Professor, Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey-New Jersey Medical School; Fellow, American College of Sports Medicine

Gerard A Malanga, MD is a member of the following medical societies: Alpha Omega Alpha, American Institute of Ultrasound in Medicine, North American Spine Society, International Spine Intervention Society, American Academy of Physical Medicine and Rehabilitation, American College of Sports Medicine

Disclosure: Received honoraria from Cephalon for speaking and teaching; Received honoraria from Endo for speaking and teaching; Received honoraria from Genzyme for speaking and teaching; Received honoraria from Prostakan for speaking and teaching; Received consulting fee from Pfizer for speaking and teaching.


Emily Harold, MD Staff Physician, Department of Internal Medicine, University of Utah Hospital

Disclosure: Nothing to disclose.

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Posterior (dorsal) view of the wrist.
Anterior palmar view.
Anteroposterior view of the wrist.
Lateral view of the wrist.
Oblique view of the wrist.
Computed tomography scan of the wrist.
Lateral computed tomography scan of the wrist.
Reconstruction of the hamate fracture.
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