Renal Cortical Necrosis Treatment & Management

  • Author: Prasad Devarajan, MD; Chief Editor: Craig B Langman, MD   more...
 
Updated: May 26, 2011
 

Approach Considerations

The cornerstones of renal cortical necrosis therapy are to restore hemodynamic stability, institute early dialytic therapy, and treat the underlying cause of the disease.

Most cases of renal cortical necrosis initially require intensive care.

Next

Dialysis

Early institution of dialysis treatment for renal failure is crucial for patients who are oliguric.

Most patients require an access (eg, hemocatheter, peritoneal dialysis catheter) to institute dialysis.

Previous
Next

Dietary Measures

Ensure adequate energy intake.

Patients with compromised kidney function require a low-potassium, low-phosphorus diet.

Previous
Next

Activity Restriction

Activity should continue as tolerated.

Previous
Next

Consultations

Consult a nephrologist to manage acute renal failure and for ongoing chronic renal replacement therapy.

Consultation with other specialties may be needed, depending on the etiology of the renal cortical necrosis.

Previous
Proceed to Medication
 
 
Contributor Information and Disclosures
Author

Prasad Devarajan, MD  Louise M Williams Endowed Chair in Pediatrics, Professor of Pediatrics and Developmental Biology, Director of Nephrology and Hypertension, Director of Clinical Nephrology Laboratories, Chief Executive Officer of Dialysis Unit, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine

Prasad Devarajan, MD is a member of the following medical societies: American Heart Association, American Society of Nephrology, American Society of Pediatric Nephrology, National Kidney Foundation, and Society for Pediatric Research

Disclosure: Nothing to disclose.

Specialty Editor Board

Laurence Finberg, MD  Clinical Professor, Department of Pediatrics, University of California, San Francisco, School of Medicine and Stanford University School of Medicine

Laurence Finberg, MD is a member of the following medical societies: American Medical Association

Disclosure: Nothing to disclose.

Mary L Windle, PharmD  Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Luther Travis, MD  Professor Emeritus, Departments of Pediatrics, Nephrology and Diabetes, University of Texas Medical Branch School of Medicine

Luther Travis, MD is a member of the following medical societies: Alpha Omega Alpha, American Federation for Medical Research, International Society of Nephrology, and Texas Pediatric Society

Disclosure: Nothing to disclose.

Chief Editor

Craig B Langman, MD  The Isaac A Abt, MD, Professor of Kidney Diseases, Northwestern University, The Feinberg School of Medicine; Division Head of Kidney Diseases, Children's Memorial Hospital

Craig B Langman, MD is a member of the following medical societies: American Academy of Pediatrics, American Society of Nephrology, and International Society of Nephrology

Disclosure: Merck Grant/research funds None; NIH Grant/research funds None; Raptor Pharmaceuticals, Inc Grant/research funds None; Alexion Pharmaceuticals, Inc. Grant/research funds None

References
  1. Kamioka I, Nozu K, Fujita T, Kaito H, Tanaka R, Yoshiya K, et al. Prognosis and pathological characteristics of five children with non-Shiga toxin-mediated hemolytic uremic syndrome. Pediatr Int. Apr 2007;49(2):196-201. [Medline].

  2. Prakash J, Vohra R, Wani IA, Murthy AS, Srivastva PK, Tripathi K, et al. Decreasing incidence of renal cortical necrosis in patients with acute renal failure in developing countries: a single-centre experience of 22 years from Eastern India. Nephrol Dial Transplant. Apr 2007;22(4):1213-7. [Medline].

  3. Ali A, Ali MA, Ali MU, Mohammad S. Hospital outcomes of obstetrical-related acute renal failure in a tertiary care teaching hospital. Ren Fail. 2011;33(3):285-90. [Medline].

  4. Papnicolaou N, Francis IR, Casalino DD, Arellano RS, Baumgarten DA, Curry NS, et al. ACR Appropriateness Criteria renal failure. [online publication]. Reston, VA: American College of Radiology (ACR); 2008.

  5. Archer L, Kilburn-Toppin F, Sneddon K, et al. A "fussy eater" with renal failure. Lancet. Feb 20 2010;375(9715):696. [Medline].

  6. Krishna GS, Kishore KC, Sriram NP, et al. Bilateral renal cortical necrosis in acute pancreatitis. Indian J Nephrol. Jul 2009;19(3):125. [Medline]. [Full Text].

Previous
Next
 
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2012 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.