eMedicine Specialties > Pediatrics: Surgery > Otolaryngology

Nasal Polyps: Follow-up

Author: John E McClay, MD, Associate Professor of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Children's Hospital of Dallas, University of Texas Southwestern Medical School
Contributor Information and Disclosures

Updated: Oct 22, 2008

Follow-up

Further Inpatient Care

  • Historically, children diagnosed with cystic fibrosis (CF) already had digestive and pulmonary disease and were the children with the more severe form of disease. These children were often treated with intravenous antibiotics directed at the most common pathogens found in the lungs and the sinuses (eg, Pseudomonas aeruginosa, Staphylococcus aureus), both preoperatively and postoperatively. Additionally, these children had pulmonary toilet to increase their lung function in the perioperative period, including intravenous steroids, percussion therapy, and inhaled bronchodilators. Much of this process can now be performed on an outpatient basis, depending on the severity of the associated disease.
  • For patients with severe asthma and polyposis requiring surgery, postoperative admission for observation of respiratory compromise or spasm is determined on an individual basis.
  • Outpatient surgery is usually performed for older children undergoing endoscopic sinus surgery (ESS) for nasal polyposis without coexisting medical conditions.

Further Outpatient Care

  • Closely monitor children with benign multiple nasal polyps, whatever the cause, because recurrence is likely, whether medically or surgically treated. Postoperative follow-up should occur 3-4 times the first month to monitor healing of the sinus cavities; frequency depends on the patient's own geographic location and symptoms.
  • A patient with CF can be monitored symptomatically because surgery is not performed until these patients are symptomatic, even if nasal polyposis is seen on CT scan or nasal endoscopy. Certainly, each patient is treated on an individual basis.
  • For polyps associated with allergic fungal sinusitis (AFS), close follow-up by an otolaryngologist is recommended until the patient is deemed free of disease, which may be several years or more.
  • Any accumulation of fungus may accelerate the antigenic process, which causes symptoms and disease to recur. Recurrence is especially common for polyps, which may be controlled more simply and effectively if recognized early.
  • Small nasal polyps are recognized early on a routine follow-up in patients with benign multiple nasal polyps.
  • Other diseases may be treated medically or with smaller surgical procedures. For diseases resulting in nasal polyps other than benign multiple nasal polyps, the need for inpatient or outpatient care is determined by the extent of disease, symptoms and situation of the patient, and associated medical conditions.

Inpatient & Outpatient Medications

Deterrence/Prevention

Complications

  • Massive polyposis or a single large polyp (eg, an antral-choanal polyp [Media files 4-12]) that obstructs the nasal cavities and/or nasopharynx can cause obstructive sleep symptoms and chronic mouth breathing. Rarely, massive polyposis, observed in CF (Media files 1-3) and in AFS (Media file 41) can alter the craniofacial structure. This can result in proptosis, hypertelorism, and diplopia (see Media files 45-46).
  • In an article submitted for publication, the author reported that 40% of children (compared with 10% of adults) with AFS presented with craniofacial abnormalities. Massive polyposis rarely causes enough extrinsic compression on the optic nerve to decrease visual acuity. One study reported that 3 of 82 patients with AFS had vision changes from compression of the optic nerve in the sphenoid sinus that resolved over time with removal of disease. However, because these polyps are slow growing, they usually cause no neurological symptoms, even when they extend into the intracranial cavity.

Prognosis

  • Polyposis recurrence is common following treatment with medical or surgical therapy if multiple benign polyps are present (see Surgical Care). Single large polyps (eg, antral-choanal polyps) are less likely to recur. The literature contains sparse data comparing treatments.

Patient Education

  • Educating patients about the chronicity of the disease is important to make them aware of the recurrent nature of the problem.

Miscellaneous

Medicolegal Pitfalls

Unfortunately, many processes that affect the nasal cavity cause the same symptoms. Frequent upper respiratory tract infections, allergic rhinitis, nonallergic rhinitis, chronic sinusitis, recurrent acute sinusitis, adenoid hypertrophy, and chronic adenoiditis often create symptoms similar to those caused by nasal polyps or tumors. Thus, nasal polyps or tumors may be present for some time before being diagnosed, possibly leading the patient or the patient's parents to assume a delayed diagnosis.

This is a difficult problem for physicians and must be delicately handled by all caregivers. However, failure to recognize signs and symptoms of advanced disease that affect other areas of the face, head, or neck (eg, paresthesias of the face, alteration of the craniofacial structure, significant persistent epistaxis, neurological symptoms, cranial nerve abnormalities) could expose patients to complications that could have been avoided if those symptoms were discovered earlier.

 


More on Nasal Polyps

Overview: Nasal Polyps
Differential Diagnoses & Workup: Nasal Polyps
Treatment & Medication: Nasal Polyps
Follow-up: Nasal Polyps
Multimedia: Nasal Polyps
References

References

  1. Bernstein JM, Gorfien J, Noble B. Role of allergy in nasal polyposis: a review. Otolaryngol Head Neck Surg. Dec 1995;113(6):724-32. [Medline].

  2. Tos M, Sasaki Y, Ohnishi M, Larsen P, Drake-Lee AB. Fireside conference 2. Pathogenesis of nasal polyps. Rhinol Suppl. 1992;14:181-5. [Medline].

  3. Stammberger H. Surgical treatment of nasal polyps: past, present, and future. Allergy. 1999;54 Suppl 53:7-11. [Medline].

  4. Mabry RL, Marple BF, Folker RJ, Mabry CS. Immunotherapy for allergic fungal sinusitis: three years' experience. Otolaryngol Head Neck Surg. Dec 1998;119(6):648-51. [Medline].

  5. Holmstrom M. Clinical performance of fluticasone propionate nasal drops. Allergy. 1999;54 Suppl 53:21-5. [Medline].

  6. Lund VJ, Flood J, Sykes AP, Richards DH. Effect of fluticasone in severe polyposis. Arch Otolaryngol Head Neck Surg. May 1998;124(5):513-8. [Medline].

  7. Andrews AE, Bryson JM, Rowe-Jones JM. Site of origin of nasal polyps: relevance to pathogenesis and management. Rhinology. Sep 2005;43(3):180-4. [Medline].

  8. Babinski D, Trawinska-Bartnicka M. Rhinosinusitis in cystic fibrosis: not a simple story. Int J Pediatr Otorhinolaryngol. May 2008;72(5):619-24. [Medline].

  9. Bachert C, Watelet JB, Gevaert P, Van Cauwenberge P. Pharmacological management of nasal polyposis. Drugs. 2005;65(11):1537-52. [Medline].

  10. Bateman ND, Shahi A, Feeley KM, Woolford TJ. Activated eosinophils in nasal polyps: a comparison of asthmatic and non-asthmatic patients. Clin Otolaryngol. Jun 2005;30(3):221-5. [Medline].

  11. Bernstein JM. Update on the molecular biology of nasal polyposis. Otolaryngol Clin North Am. Dec 2005;38(6):1243-55. [Medline].

  12. Blaiss MS. Expanding the evidence base for the medical treatment of nasal polyposis. J Allergy Clin Immunol. Dec 2005;116(6):1272-4. [Medline].

  13. Bugten V, Nordgard S, Steinsvag S. Long-term effects of postoperative measures after sinus surgery. Eur Arch Otorhinolaryngol. May 2008;265(5):531-7. [Medline].

  14. Dunlop G, Scadding GK, Lund VJ. The effect of endoscopic sinus surgery on asthma: management of patients with chronic rhinosinusitis, nasal polyposis, and asthma. Am J Rhinol. Jul-Aug 1999;13(4):261-5. [Medline].

  15. Eghtedari F, Cheraghzadeh SR, Kashef MA, Monabati A, Kashef S. Agreement rate of skin prick test with tissue eosinophil count in patients with nasal polyps. Iran J Allergy Asthma Immunol. Jun 2007;6(2):89-92. [Medline].

  16. Eliashar R, Levi-Schaffer F. The role of the eosinophil in nasal diseases. Curr Opin Otolaryngol Head Neck Surg. Jun 2005;13(3):171-5. [Medline].

  17. European position paper on rhinosinusitis and nasal polyps. Rhinol Suppl. 2005;1-87. [Medline].

  18. Hedman J, Kaprio J, Poussa T, Nieminen MM. Prevalence of asthma, aspirin intolerance, nasal polyposis and chronic obstructive pulmonary disease in a population-based study. Int J Epidemiol. Aug 1999;28(4):717-22. [Medline].

  19. Kieff DA, Busaba NY. Efficacy of montelukast in the treatment of nasal polyposis. Ann Otol Rhinol Laryngol. Dec 2005;114(12):941-5. [Medline].

  20. Kramer MF, Rasp G. Nasal polyposis: eosinophils and interleukin-5. Allergy. Jul 1999;54(7):669-80. [Medline].

  21. Lee CH, Lee KS, Rhee CS, Lee SO, Min YG. Distribution of rantes and interleukin-5 in allergic nasal mucosa and nasal polyps. Ann Otol Rhinol Laryngol. Jun 1999;108(6):594-8. [Medline].

  22. Lund V. Advances in the treatment of nasal polypopsis. Introduction. Allergy. 1999;54 Suppl 53:5-6. [Medline].

  23. Lund VJ. The effect of sinonasal surgery on asthma. Allergy. 1999;54 Suppl 57:141-5. [Medline].

  24. Morinaka S, Nakamura H. Inflammatory cells in nasal mucosa and nasal polyps. Auris Nasus Larynx. Jan 2000;27(1):59-64. [Medline].

  25. Mygind N. Advances in the medical treatment of nasal polyps. Allergy. 1999;54 Suppl 53:12-6. [Medline].

  26. Mygind N, Dahl R, Bachert C. Nasal polyposis, eosinophil dominated inflammation, and allergy. Thorax. Oct 2000;55 Suppl 2:S79-83. [Medline].

  27. Nakamura H, Kawasaki M, Higuchi Y, Takahashi S. Effects of sinus surgery on asthma in aspirin triad patients. Acta Otolaryngol. 1999;119(5):592-8. [Medline].

  28. Norlander T, Bronnegard M, Stierna P. The relationship of nasal polyps, infection, and inflammation. Am J Rhinol. Sep-Oct 1999;13(5):349-55. [Medline].

  29. Pawliczak R, Lewandowska-Polak A, Kowalski ML. Pathogenesis of nasal polyps: an update. Curr Allergy Asthma Rep. Nov 2005;5(6):463-71. [Medline].

  30. Radenne F, Lamblin C, Vandezande LM, et al. Quality of life in nasal polyposis. J Allergy Clin Immunol. Jul 1999;104(1):79-84. [Medline].

  31. Rudack C, Bachert C, Stoll W. Effect of prednisolone on cytokine synthesis in nasal polyps. J Interferon Cytokine Res. Sep 1999;19(9):1031-5. [Medline].

  32. Slavin SA. The rectus abdominis myocutaneous flap: observation and refinements. Plast Reconstr Surg. Feb 1983;71(2):280-1. [Medline].

  33. Small CB, Hernandez J, Reyes A, et al. Efficacy and safety of mometasone furoate nasal spray in nasal polyposis. J Allergy Clin Immunol. Dec 2005;116(6):1275-81. [Medline].

  34. Uneri C, Ozturk O, Polat S, Yuksel M, Haklar G. Determination of reactive oxygen species in nasal polyps. Rhinology. Sep 2005;43(3):185-9. [Medline].

  35. Young MC. Rhinitis, sinusitis, and polyposis. Allergy Asthma Proc. Jul-Aug 1998;19(4):211-8. [Medline].

Further Reading

Contributor Information and Disclosures

Author

John E McClay, MD, Associate Professor of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, Children's Hospital of Dallas, University of Texas Southwestern Medical School
John E McClay, MD is a member of the following medical societies: American Academy of Otolaryngic Allergy, American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, and American Medical Association
Disclosure: Nothing to disclose.

Medical Editor

Orval Brown, MD, Director of Otolaryngology Clinic, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas
Orval Brown, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics, American Bronchoesophagological Association, American College of Surgeons, American Medical Association, American Society of Pediatric Otolaryngology, Society for Ear, Nose and Throat Advances in Children, and Society of University Otolaryngologists-Head and Neck Surgeons
Disclosure: Nothing to disclose.

Pharmacy Editor

Mary L Windle, PharmD, Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy, Pharmacy Editor, eMedicine
Disclosure: Pfizer Inc Stock Investment from financial planner; Avanir Pharma Stock Investment from financial planner ; WebMD Salary and stock Employment and investment from financial planner

Managing Editor

Alan D Murray, MD, Pediatric Otolaryngologist, ENT for Children; Full-Time Staff, Medical City Dallas Children's Hospital; Consulting Staff, Department of Otolaryngology, Medical Center of Lewisville, Children's Medical Center at Dallas, Cook Children's Medical Center; Full-Time Staff, Texas Pediatric Surgery Center, The Pediatric Surgery Center
Alan D Murray, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics, American College of Surgeons, American Society of Pediatric Otolaryngology, Society for Ear, Nose and Throat Advances in Children, and Texas Medical Association
Disclosure: Nothing to disclose.

CME Editor

Paul D Petry, DO, FACOP, FAAP, Consulting Staff, Freeman Pediatric Care, Freeman Health System
Paul D Petry, DO, FACOP, FAAP is a member of the following medical societies: American Academy of Osteopathy, American Academy of Pediatrics, American College of Osteopathic Pediatricians, and American Osteopathic Association
Disclosure: Nothing to disclose.

Chief Editor

Glenn C Isaacson, MD, FACS, FAAP, Professor of Otolaryngology-Head and Neck Surgery and Pediatrics, Temple University School of Medicine
Glenn C Isaacson, MD, FACS, FAAP is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics, American Bronchoesophagological Association, American College of Surgeons, American Laryngological Rhinological and Otological Society, American Society of Pediatric Otolaryngology, and Society of University Otolaryngologists-Head and Neck Surgeons
Disclosure: Covidien Honoraria Consulting

 
 
HONcode

We subscribe to the
HONcode principles of the
Health On the Net Foundation

All material on this website is protected by copyright, Copyright© 1994- by Medscape.
This website also contains material copyrighted by 3rd parties.

DISCLAIMER: The content of this Website is not influenced by sponsors. The site is designed primarily for use by qualified physicians and other medical professionals. The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only. In no way should it be considered as offering medical advice. Please check with a physician if you suspect you are ill.