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Pierre Robin Sequence Medication

  • Author: Marie M Tolarova, MD, PhD, DSc; Chief Editor: Ravindhra G Elluru, MD, PhD  more...
 
Updated: Jul 11, 2016
 
 

Medication Summary

Drug therapy currently is not a component of standard care for Pierre Robin sequence (PRS). See Treatment.

 
Contributor Information and Disclosures
Author

Marie M Tolarova, MD, PhD, DSc Professor and Executive Director Pacific Craniofacial Team and Cleft Prevention Program, University of the Pacific, Dugoni School of Dentistry

Marie M Tolarova, MD, PhD, DSc is a member of the following medical societies: American Cleft Palate-Craniofacial Association, International Association for Dental Research, American Society of Human Genetics

Disclosure: Nothing to disclose.

Specialty Editor Board

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Alan D Murray, MD Pediatric Otolaryngologist, ENT for Children; Full-Time Staff, Medical City Dallas Children's Hospital; Consulting Staff, Department of Otolaryngology, Children's Medical Center at Dallas, Cook Children's Medical Center; Full-Time Staff, Texas Pediatric Surgery Center, Cook Children's Pediatric Surgery Center Plano

Alan D Murray, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngology-Head and Neck Surgery, American Society of Pediatric Otolaryngology, Society for Ear, Nose and Throat Advances in Children, American Academy of Pediatrics, American College of Surgeons, Texas Medical Association

Disclosure: Nothing to disclose.

Chief Editor

Ravindhra G Elluru, MD, PhD Professor, Wright State University, Boonshoft School of Medicine; Pediatric Otolaryngologist, Department of Otolaryngology, Dayton Children's Hospital Medical Center

Ravindhra G Elluru, MD, PhD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics, American Bronchoesophagological Association, American College of Surgeons, American Medical Association, Association for Research in Otolaryngology, Society for Ear, Nose and Throat Advances in Children, Triological Society, American Society for Cell Biology

Disclosure: Nothing to disclose.

Acknowledgements

Orval Brown, MD Director of Otolaryngology Clinic, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas

Orval Brown, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics, American Bronchoesophagological Association, American College of Surgeons, American Medical Association, American Society of Pediatric Otolaryngology, Society for Ear, Nose and Throat Advances in Children, and Society of University Otolaryngologists-Head and Neck Surgeons

Disclosure: Nothing to disclose.

Alex M Espinoza, MD Medical Director, Infant Follow-up Clinic, Department of Neonatology, Alta Bates Medical Center and John Muir Medical Center

Disclosure: Nothing to disclose.

Craig W Senders, MD Professor and Program Director, Department of Otolaryngology, University of California at Davis School of Medicine; Director, Cleft and Craniofacial Team, Department of Otolaryngology, University of California at Davis Medical Center

Disclosure: Nothing to disclose.

References
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Three-week-old baby boy affected with nonsyndromic Pierre Robin sequence.
One-month-old baby affected with nonsyndromic Pierre Robin sequence.
Child with nonsyndromic Pierre Robin sequence at age 4 years. Profile is almost normal because of catchup growth.
Child with nonsyndromic Pierre Robin sequence at age 4 years.
U-shaped and V-shaped cleft palates.
Eight-year-old boy with Stickler syndrome. Note flat, hypotonic face and small mandible. Patient also has U-shaped, wide cleft palate (CP). His mandible does not show catchup growth. Patient is mouth-breather and snores and is using CP as airway. Closing of CP without preparation would compromise airway passage. Authors recommend placing an obturator (perhaps with speech bulb) for couple of hours daily at first, then gradually increasing time. After few months, when child will have changed breathing pattern, palate can be closed.
Eight-year-old boy with Stickler syndrome. Note flat, hypotonic face and small mandible. Mandible does not show catchup growth.
Eight-year-old boy with Stickler syndrome. Note U-shaped, wide cleft palate.
Pierre Robin sequence in some recognized and unrecognized syndromes.
Pierre Robin sequence and complexes.
Robin sequences and complexes.
Child with Pierre Robin sequence before distraction osteogenesis.
Distraction osteogenesis is completed, and bone is consolidating.
 
 
 
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