eMedicine Specialties > Pediatrics: General Medicine > Parasitology
Fascioliasis: Follow-up
Updated: Jan 22, 2009
Follow-up
Further Inpatient Care
- The condition of the patient with fascioliasis determines inpatient care versus outpatient care.
Further Outpatient Care
- No particular outpatient care is required once treatment is successfully completed.
Transfer
- Transfer is necessary only when specialized services or care (see Consultations) are unavailable.
Deterrence/Prevention
- Fascioliasis can be prevented through public education about avoiding consumption of contaminated water plants, water, and raw liver.
Complications
- Severe anemia and, less commonly, pancreatitis, occur in children more frequently than in adults.
- Rare complications include ectopic foci of infection, hemoperitoneum, subcapsular hematoma, hepatic mass, cholecystitis, ascending cholangitis, hemobilia from ulceration of the biliary epithelium, gallstones, and sclerosing cholangitis.
Prognosis
- Prognosis is excellent with adequate therapy.
Patient Education
- Advise patients to avoid high-risk behaviors (ie, consumption of contaminated water plants, water, raw liver).
- For excellent patient education resources, visit eMedicine's Esophagus, Stomach, and Intestine Center and Liver, Gallbladder, and Pancreas Center. Also, see eMedicine's patient education articles, Abdominal Pain in Children and Pancreatitis.
Miscellaneous
Medicolegal Pitfalls
- Failure to consider the diagnosis for patients who may have had exposure to fluke worms
More on Fascioliasis |
| Overview: Fascioliasis |
| Differential Diagnoses & Workup: Fascioliasis |
| Treatment & Medication: Fascioliasis |
Follow-up: Fascioliasis |
| Multimedia: Fascioliasis |
| References |
| « Previous Page | Next Page » |
References
Haseeb AN, el-Shazly AM, Arafa MA, Morsy AT. A review on fascioliasis in Egypt. J Egypt Soc Parasitol. Apr 2002;32(1):317-54. [Medline].
Dreyfuss G, Vignoles P, Rondelaud D. Fasciola hepatica: epidemiological surveillance of natural watercress beds in central France. Parasitol Res. Mar 2005;95(4):278-82. [Medline].
el-Shabrawi M, el-Karaksy H, Okasha S, el-Hennawy A. Human fascioliasis: clinical features and diagnostic difficulties in Egyptian children. J Trop Pediatr. Jun 1997;43(3):162-6. [Medline].
Bacq Y, Besnier JM, Duong TH, et al. Successful treatment of acute fascioliasis with bithionol. Hepatology. Dec 1991;14(6):1066-9. [Medline].
el-Karaksy H, Hassanein B, Okasha S, Behairy B, Gadallah I. Human fascioliasis in Egyptian children: successful treatment with triclabendazole. J Trop Pediatr. Jun 1999;45(3):135-8. [Medline].
Dowidar N, El Sayad M, Osman M, Salem A. Endoscopic therapy of fascioliasis resistant to oral therapy. Gastrointest Endosc. Sep 1999;50(3):345-51. [Medline].
Apt W, Aguilera X, Vega F, et al. Treatment of human chronic fascioliasis with triclabendazole: drug efficacy and serologic response. Am J Trop Med Hyg. Jun 1995;52(6):532-5. [Medline].
Arauco R, Zetola NM, Calderon F, Seas C. Human fascioliasis: a case of hyperinfection and an update for clinicians. Foodborne Pathog Dis. 2007;4(3):305-12. [Medline].
Arjona R, Riancho JA, Aguado JM, Salesa R, Gonzalez-Macias J. Fascioliasis in developed countries: a review of classic and aberrant forms of the disease. Medicine (Baltimore). Jan 1995;74(1):13-23. [Medline].
Ashrafi K, Valero MA, Massoud J, et al. Plant-borne human contamination by fascioliasis. Am J Trop Med Hyg. Aug 2006;75(2):295-302. [Medline].
Bunnag D, Bunnag T, Goldsmith R. Liver fluke infections. In: Hunter's Tropical Medicine. 1991:818-27.
Cheng AC, Zakhidov BO, Babadjonova LJ, Rogers NK, McCollum CJ, Hillyer GV. A 6-year-old boy with facial swelling and monocular blindness. Clin Infect Dis. Nov 1 2007;45(9):1207, 1238-9. [Medline].
Clark BM, Lloyd BA, Christopher GW, Foody WF. A young man from Peru with fever and abdominal pain. Clin Infect Dis. Mar 15 2005;40(6):842-3, 879-80. [Medline].
Diaz E, Mondragon J, Ramirez E, Bernal R. Epidemiology and control of intestinal parasites with nitazoxanide in children in Mexico. Am J Trop Med Hyg. Apr 2003;68(4):384-5. [Medline]. [Full Text].
Dreyfuss G, Rondelaud D. Biodiversity of flukes. Parasite. Sep 2008;15(3):282-5. [Medline].
Espinoza JR, Maco V, Marcos L, Saez S, Neyra V, Terashima A. Evaluation of Fas2-ELISA for the serological detection of Fasciola hepatica infection in humans. Am J Trop Med Hyg. May 2007;76(5):977-82. [Medline].
Fox LM, Saravolatz LD. Nitazoxanide: a new thiazolide antiparasitic agent. Clin Infect Dis. Apr 15 2005;40(8):1173-80. [Medline].
Garcia HH, Moro PL, Schantz PM. Zoonotic helminth infections of humans: echinococcosis, cysticercosis and fascioliasis. Curr Opin Infect Dis. Oct 2007;20(5):489-94. [Medline].
Graham CS, Brodie SB, Weller PF. Imported Fasciola hepatica Infection in the United States and Treatment with Triclabendazole. Clin Infect Dis. Jul 1 2001;33(1):1-5. [Medline].
Hien TT, Truong NT, Minh NH, et al. A randomized controlled pilot study of artesunate versus triclabendazole for human fascioliasis in central Vietnam. Am J Trop Med Hyg. Mar 2008;78(3):388-92. [Medline].
Kabaalioglu A, Apaydin A, Sindel T, Luleci E. US-guided gallbladder aspiration: a new diagnostic method for biliary fascioliasis. Eur Radiol. 1999;9(5):880-2. [Medline].
Kaewpitoon N, Kaewpitoon SJ, Pengsaa P, Pilasri C. Knowledge, attitude and practice related to liver fluke infection in northeast Thailand. World J Gastroenterol. Mar 28 2007;13(12):1837-40. [Medline].
Katz M, Despommier DD, Gwadz RW. Fasciola hepatica. In: Parasitic Diseases. 1989:112-6.
Keiser J, Utzinger J. Chemotherapy for major food-borne trematodes: a review. Expert Opin Pharmacother. Aug 2004;5(8):1711-26. [Medline].
Le TH, De NV, Agatsuma T, Blair D, Vercruysse J, Dorny P. Molecular confirmation that Fasciola gigantica can undertake aberrant migrations in human hosts. J Clin Microbiol. Feb 2007;45(2):648-50. [Medline].
Lim JH, Kim SY, Park CM. Parasitic diseases of the biliary tract. AJR Am J Roentgenol. Jun 2007;188(6):1596-603. [Medline].
Lim JH, Mairiang E, Ahn GH. Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis. Abdom Imaging. Mar-Apr 2008;33(2):157-65. [Medline].
Liu LX, Harinasuta KT. Liver and intestinal flukes. Gastroenterol Clin North Am. Sep 1996;25(3):627-36. [Medline].
Lopez-Velez R, Dominguez-Castellano A, Garron C. Successful treatment of human fascioliasis with triclabendazole. Eur J Clin Microbiol Infect Dis. Jul 1999;18(7):525-6. [Medline].
MacLean JD, Cross J, Mahanty S. Liver, lung, and intestinal fluke infections. In: Tropical Infectious Diseases: Principles, Pathogens, & Practice. 1999:1039-57.
Makay O, Gurcu B, Caliskan C, Nart D, Tuncyurek M, Korkut M. Ectopic fascioliasis mimicking a colon tumor. World J Gastroenterol. May 14 2007;13(18):2633-5. [Medline].
Mannstadt M, Sing A, Leitritz L, Brenner-Maucher K, Bogner J. Conservative management of biliary obstruction due to Fasciola hepatica. Clin Infect Dis. Nov 2000;31(5):1301-3. [Medline].
Mansour-Ghanaei F, Shafaghi A, Fallah MS. The effect of metronidazole in treating human fascioliasis. Med Sci Monit. Oct 2003;9(10):PI127-30. [Medline].
Marcos L, Maco V, Samalvides F. Risk factors for Fasciola hepatica infection in children: a case-control study. Trans R Soc Trop Med Hyg. Feb 2006;100(2):158-66. [Medline].
Marcos LA, Tagle M, Terashima A, et al. Natural history, clinicoradiologic correlates, and response to triclabendazole in acute massive fascioliasis. Am J Trop Med Hyg. Feb 2008;78(2):222-7. [Medline].
Marcos LA, Terashima A, Gotuzzo E. Update on hepatobiliary flukes: fascioliasis, opisthorchiasis and clonorchiasis. Curr Opin Infect Dis. Oct 2008;21(5):523-30. [Medline].
McManus DP, Dalton JP. Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica. Parasitology. 2006;133 Suppl:S43-61. [Medline].
Nawa Y, Hatz C, Blum J. Sushi delights and parasites: the risk of fishborne and foodborne parasitic zoonoses in Asia. Clin Infect Dis. Nov 1 2005;41(9):1297-303. [Medline].
Noyer CM, Coyle CM, Werner C, et al. Hypereosinophilia and liver mass in an immigrant. Am J Trop Med Hyg. Jun 2002;66(6):774-6. [Medline]. [Full Text].
Pearson RD. Nitazoxanide As Treatment of Intestinal Parasites in Children. Curr Infect Dis Rep. Feb 2004;6(1):25-26. [Medline].
Pearson RD, Weller PF, Guerrant. Chemotherapy of parasitic diseases. In: Tropical Infectious Diseases: Principles, Pathogens, & Practice. 1999:215-37.
Price TA, Tuazon CU, Simon GL. Fascioliasis: case reports and review. Clin Infect Dis. Sep 1993;17(3):426-30. [Medline].
Rana SS, Bhasin DK, Nanda M, Singh K. Parasitic infestations of the biliary tract. Curr Gastroenterol Rep. Apr 2007;9(2):156-64. [Medline].
Richter J, Knipper M, Gobels K. Fascioliasis. Curr Treatment Options Infect Dis. 2002;4:313-7.
Robertson J, Shilkofski N. Drug doses. In: The Harriet Lane Handbook: A Manual for Pediatric House Officers. Philadelphia, Pa: Mosby; 2005:679-1009.
Sripa B, Kaewkes S, Sithithaworn P, Mairiang E, Laha T, Smout M. Liver fluke induces cholangiocarcinoma. PLoS Med. Jul 2007;4(7):e201. [Medline].
Tantrawatpan C, Maleewong W, Wongkham C, et al. Serodiagnosis of human fascioliasis by a cystatin capture enzyme-linked immunosorbent assay with recombinant Fasciola gigantica cathepsin L antigen. Am J Trop Med Hyg. Jan 2005;72(1):82-6. [Medline]. [Full Text].
Turner JA. Trematodes. In: Textbook of Pediatric Infectious Diseases. 2004:2817-25.
Valero MA, Santana M, Morales M, et al. Risk of gallstone disease in advanced chronic phase of fascioliasis: an experimental study in a rat model. J Infect Dis. Sep 1 2003;188(5):787-93. [Medline].
Walker SM, McKinstry B, Boray JC, et al. Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro. Parasitol Res. Dec 2004;94(6):427-38. [Medline].
Xuan le T, Hung NT, Waikagul J. Cutaneous fascioliasis: a case report in Vietnam. Am J Trop Med Hyg. May 2005;72(5):508-9. [Medline]. [Full Text].
Further Reading
Keywords
fascioliasis, abdominal pain, airway obstruction, ascending cholangitis, biliary colic, cattle, dysphagia, Fasciola gigantica, F gigantica, Fg, Fasciola hepatica, F hepatica, Fh, foreign body sensation, halzoun (Lebanese), hepatomegaly, jaundice, liver fluke, marrerra (Sudanese), pancreatitis, parasitic infection, pharyngitis, sashimi, severe anemia, sheep liver fluke, sheep liver fluke disease, subcutaneous nodules
Follow-up: Fascioliasis