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BYETTA® offers sustained A1C control with a secondary benefit of weight loss


BYETTA provided a 2.1% reduction in A1C in poorly controlled patients through 2.5 years

A1C reduction by baseline
Mean baseline A1C: 9.7%

  Patients with a baseline A1C of <9% (mean: 7.8%) experienced, on average, a 0.7% reduction in A1C at 2.5 years with BYETTA (n = 182).*[1]

BYETTA sustained reductions in A1C across all patients through 2.5 years


  Mean change in A1C from baseline*[1] was -1.2 % at 30 weeks (n = 241) and -1.1%
at 2.5 years (n = 241)

  Mean baseline A1C: 8.3%

*Initial 30-week double-blind, placebo-controlled clinical trials were continued in open-label extensions through 130 weeks with BYETTA
5 mcg or 10 mcg. Subjects (n = 241) received BYETTA 5 mcg BID for
4 weeks, BYETTA 5 mcg or 10 mcg BID for 26 weeks, BYETTA 5 mcg BID for 4 weeks, and BYETTA 10 mcg BID for 96 weeks in combination with metformin, a sulfonylurea, or both. Note: all values are means; data by completer analysis.

BYETTA helped most patients lose weight through 2.5 years


Change in body weight from baseline
*Initial 30-week double-blind, placebo-controlled clinical trials were continued in open-label extensions through 130 weeks with BYETTA
5 mcg or 10 mcg. Subjects (n = 241) received BYETTA 5 mcg BID for
4 weeks, BYETTA 5 mcg or 10 mcg BID for 26 weeks, BYETTA 5 mcg BID for 4 weeks, and BYETTA 10 mcg BID for 96 weeks in combination with metformin, a sulfonylurea, or both. Note: all values are means; data by completer analysis.

BYETTA is not indicated for the management of obesity.




BYETTA is indicated as adjunctive therapy to improve glycemic control in patients with type 2 diabetes mellitus who are taking metformin, a sulfonylurea, a thiazolidinedione, a combination of metformin and a sulfonylurea, or a combination of metformin and a thiazolidinedione, but have not achieved adequate glycemic control.

For Important Safety Information, please click here and for complete safety profile and other important prescribing considerations, see the full Prescribing Information.

References