Afebrile Pneumonia Syndrome Differential Diagnoses

Updated: Jul 24, 2018
  • Author: Dagnachew (Dagne) Assefa, MD, FAAP, FCCP; Chief Editor: Girish D Sharma, MD, FCCP, FAAP  more...
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Diagnostic Considerations

Some organisms acquired perinatally may not cause illness until later in infancy, including Chlamydophila pneumoniae,Ureaplasma urealyticum,Mycoplasma hominis, cytomegalovirus, and Pneumocystis jiroveci. Infants infected with these organisms present between age 4-11 weeks with an afebrile pneumonia characterized by a staccato cough, tachypnea, and, occasionally, hypoxia.

Infants with bacterial pneumonia often are febrile, but those with viral pneumonia or pneumonia caused by atypical organisms may have a low-grade fever or may be afebrile. The child's caretakers may complain that the child is wheezing or has noisy breathing.

Differential Diagnoses