Pediatric Sarcoidosis Differential Diagnoses

Updated: Feb 01, 2016
  • Author: Girish D Sharma, MD, FCCP, FAAP; Chief Editor: Michael R Bye, MD  more...
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DDx

Diagnostic Considerations

The differential diagnosis of sarcoidosis depends largely on the clinical presentation of the disease. Rule out granulomatous pulmonary infections, especially those caused by mycobacteria and fungi. Exclude neoplastic diseases, such as lymphoma, in cases with hilar adenopathy. Hypercalcemia in sarcoidosis may mimic metabolic disorders, such as primary hyperparathyroidism. Early onset sarcoidosis is often misdiagnosed as systemic-onset JRA. [21] Rarely, severe symptomatic bone marrow involvement may mimic numerous infectious and neoplastic disorders.

Differential Diagnoses