Pediatric Antiphospholipid Antibody Syndrome Questions & Answers

Updated: Dec 11, 2018
  • Author: Barry L Myones, MD; Chief Editor: Lawrence K Jung, MD  more...
  • Print
Questions & Answers

Overview

What is pediatric antiphospholipid antibody syndrome?

What are the diagnostic clinical criteria for pediatric antiphospholipid antibody syndrome?

What are the diagnostic lab criteria for pediatric antiphospholipid antibody syndrome?

What is the pathophysiology of pediatric antiphospholipid antibody syndrome?

What is the US prevalence of pediatric antiphospholipid antibody syndrome?

What are the sexual predilections of pediatric antiphospholipid antibody syndrome?

Which age groups have the highest prevalence of pediatric antiphospholipid antibody syndrome?

What is the global prevalence of pediatric antiphospholipid antibody syndrome?

What is the mortality and morbidity associated with pediatric antiphospholipid antibody syndrome?

What are the racial predilections of pediatric antiphospholipid antibody syndrome?

Presentation

What are the signs and symptoms of pediatric antiphospholipid antibody syndrome?

Which family and medication history findings are characteristic of pediatric antiphospholipid antibody syndrome?

Which clinical history findings are characteristic of pediatric antiphospholipid antibody syndrome?

Which physical findings are characteristic of pediatric antiphospholipid antibody syndrome?

What causes pediatric antiphospholipid antibody syndrome?

DDX

What are the differential diagnoses for Pediatric Antiphospholipid Antibody Syndrome?

Workup

What is the role of lab tests in the workup of pediatric antiphospholipid antibody syndrome?

How is intrarenal, renal artery, or renal vein thrombosis identified in the workup of pediatric antiphospholipid antibody syndrome?

How is persistent thrombocytopenia or evidence of hemolytic anemia assessed in the workup of pediatric antiphospholipid antibody syndrome?

How are coexisting deficiencies of the coagulation system assessed in the workup of pediatric antiphospholipid antibody syndrome?

How are coexisting genetic polymorphisms assessed in the workup of pediatric antiphospholipid antibody syndrome?

What is the role of imaging studies in the workup of pediatric antiphospholipid antibody syndrome?

What is the role of biopsy in the workup of pediatric antiphospholipid antibody syndrome?

Which histologic findings are characteristic of pediatric antiphospholipid antibody syndrome?

Treatment

How is pediatric antiphospholipid antibody syndrome treated?

What is the role of surgery in the treatment of pediatric antiphospholipid antibody syndrome?

Which specialist consultations are beneficial to patients with pediatric antiphospholipid antibody syndrome?

Which dietary modifications are used in the treatment of pediatric antiphospholipid antibody syndrome?

Which activity modifications are used in the treatment of pediatric antiphospholipid antibody syndrome?

Medications

What is the role of medications in the treatment of pediatric antiphospholipid antibody syndrome?

Which medications in the drug class Biological response modulator are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Antilipemic Agent are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Other therapy with multiple actions are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Platelet count enhancers are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Drugs with effects on vascular endothelium, platelets, red blood cells are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Vasodilators are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Immunomodulators are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Anticoagulants are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Which medications in the drug class Antiplatelet agents are used in the treatment of Pediatric Antiphospholipid Antibody Syndrome?

Follow-up

What is included in the long-term monitoring of pediatric antiphospholipid antibody syndrome?

What is included in inpatient care for pediatric antiphospholipid antibody syndrome?

Which medications are used in the treatment of pediatric antiphospholipid antibody syndrome?

When is patient transfer indicated for the treatment of pediatric antiphospholipid antibody syndrome?

What are the possible complications of pediatric antiphospholipid antibody syndrome?

What is the prognosis of pediatric antiphospholipid antibody syndrome?

What is included in patient education about pediatric antiphospholipid antibody syndrome?