Pediatric Mixed Connective Tissue Disease Questions & Answers

Updated: Oct 24, 2018
  • Author: Marisa S Klein-Gitelman, MD, MPH; Chief Editor: Lawrence K Jung, MD  more...
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Questions & Answers

Overview

What is pediatric mixed connective-tissue disorder (MCTD)?

What is the pathophysiology of pediatric mixed connective-tissue disorder (MCTD)?

What is the US prevalence of pediatric mixed connective-tissue disorder (MCTD)?

What is the global prevalence of pediatric mixed connective-tissue disorder (MCTD)?

What is the morbidity and mortality associated with pediatric mixed connective-tissue disorder (MCTD)?

What are the racial predilections of pediatric mixed connective-tissue disorder (MCTD)?

What are the sexual predilections of pediatric mixed connective-tissue disorder (MCTD)?

Which age groups have the highest prevalence of pediatric mixed connective-tissue disorder (MCTD)?

Presentation

What are the signs and symptoms of pediatric mixed connective-tissue disorder (MCTD)?

Which physical findings are characteristic of pediatric mixed connective-tissue disorder (MCTD)?

What are the diagnostic criteria for pediatric mixed connective-tissue disorder (MCTD)?

What causes pediatric mixed connective-tissue disorder (MCTD)?

DDX

What are the differential diagnoses for Pediatric Mixed Connective Tissue Disease?

Workup

What are the diagnostic lab studies for pediatric mixed connective-tissue disorder (MCTD)?

What is the role of lab tests in the workup of pediatric mixed connective-tissue disorder (MCTD)?

What is the role of imaging studies in the workup of pediatric mixed connective-tissue disorder (MCTD)?

What is the role of nailfold capillaroscopy in the workup of pediatric mixed connective-tissue disorder (MCTD)?

What is the role of echocardiography in the workup of pediatric mixed connective-tissue disorder (MCTD)?

What is the role of pulmonary function testing in the workup of pediatric mixed connective-tissue disorder (MCTD)?

What is the role of biopsy in the workup of pediatric mixed connective-tissue disorder (MCTD)?

Which histologic findings are characteristic of pediatric mixed connective-tissue disorder (MCTD)?

How is pediatric mixed connective-tissue disorder (MCTD) staged?

Treatment

How is pediatric mixed connective-tissue disorder (MCTD) treated?

What is the role of surgery in the treatment of pediatric mixed connective-tissue disorder (MCTD)?

Which specialist consultations are beneficial to patients with pediatric mixed connective-tissue disorder (MCTD)?

Which dietary modifications are used in the treatment of pediatric mixed connective-tissue disorder (MCTD)?

Which activity modifications are used in the treatment of pediatric mixed connective-tissue disorder (MCTD)?

Medications

What is the role of medications of pediatric mixed connective-tissue disorder (MCTD)?

Which medications in the drug class Phosphodiesterase (type 5) Enzyme Inhibitor are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Rheostatic agents are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Calcium and vitamin D therapies are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Immunosuppressive agents are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Corticosteroids are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Antimalarials are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Which medications in the drug class Nonsteroidal anti-inflammatory drugs are used in the treatment of Pediatric Mixed Connective Tissue Disease?

Follow-up

What is included in long-term monitoring of pediatric mixed connective-tissue disorder (MCTD)?

When is inpatient care indicated for the treatment of pediatric mixed connective-tissue disorder (MCTD)

When is patient transfer required for the treatment of pediatric mixed connective-tissue disorder (MCTD)?

How is pediatric mixed connective-tissue disorder (MCTD) prevented?

What are the possible complications of pediatric mixed connective-tissue disorder (MCTD)?

What is the prognosis of pediatric mixed connective-tissue disorder (MCTD)?

What is included in patient education about pediatric mixed connective-tissue disorder (MCTD)?