Rhabdomyolysis Questions & Answers

Updated: Oct 14, 2018
  • Author: Marietta Morales De Guzman, MD; Chief Editor: Lawrence K Jung, MD  more...
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Questions & Answers

Overview

How does myoglobin cause rhabdomyolysis?

What are the signs and symptoms of rhabdomyolysis?

What causes rhabdomyolysis?

Which physical findings are characteristic of rhabdomyolysis?

What are the possible complications of rhabdomyolysis?

Which lab tests may be helpful in the diagnosis of rhabdomyolysis?

When are imaging studies indicated in the workup of rhabdomyolysis?

Which tests may be considered in the workup of rhabdomyolysis?

What is the initial treatment for rhabdomyolysis?

Which surgical interventions are used to treat rhabdomyolysis?

Which diet and activity modifications are used in the treatment of rhabdomyolysis?

What is rhabdomyolysis?

What is the pathophysiology of rhabdomyolysis?

What is the pathophysiology of acute kidney injury (AKI) in rhabdomyolysis?

How does trauma and muscle compression cause rhabdomyolysis?

What are the most common traumatic causes of rhabdomyolysis?

Which viral infections may cause rhabdomyolysis?

Which bacterial infections may cause rhabdomyolysis?

Which fungal infections may cause rhabdomyolysis?

What is the role of genetics in the etiology of rhabdomyolysis?

Which metabolic deficiencies may cause rhabdomyolysis?

What are the less common causes of rhabdomyolysis?

What causes toxin-mediated rhabdomyolysis?

What is the role of ethanol in the etiology of rhabdomyolysis?

Which medications may cause rhabdomyolysis?

Which drug most commonly cause rhabdomyolysis in children?

What is the role of statins in the etiology of rhabdomyolysis?

Which environmental toxins may cause rhabdomyolysis?

What are the risk factors for exertional rhabdomyolysis and renal failure?

What is the prevalence of rhabdomyolysis is the US?

What is the global prevalence of rhabdomyolysis?

Which age groups have the highest incidence of rhabdomyolysis?

What are the sexual predilections of rhabdomyolysis?

What is the prognosis of rhabdomyolysis?

What is included in patient education about rhabdomyolysis?

Presentation

What is the classic triad of rhabdomyolysis and how common is it the presentation?

Which clinical history findings are characteristic of rhabdomyolysis?

Which physical findings are characteristic of rhabdomyolysis?

Which electrolyte abnormalities are common in rhabdomyolysis?

How is compartment syndrome diagnosed and treated in rhabdomyolysis?

What are the renal complications of rhabdomyolysis?

DDX

How is rhabdomyolysis diagnosed?

Which conditions should be considered in the differential diagnosis of rhabdomyolysis?

Workup

When should a diagnosis of rhabdomyolysis be considered in children?

What is the prevalence of acute kidney injury in rhabdomyolysis?

Which lab tests are performed in the workup of rhabdomyolysis?

What is the role of serum chemistries in the workup of rhabdomyolysis?

How is the diagnosis of rhabdomyolysis confirmed?

What is the role of plasma myoglobin measurement in the diagnosis of rhabdomyolysis?

What is the role of imaging studies in the diagnosis of rhabdomyolysis?

What is the role of ECG in the workup of rhabdomyolysis?

What is the role of compartment pressure measurement in the workup of rhabdomyolysis?

Which histologic findings are characteristic of rhabdomyolysis?

Treatment

How is rhabdomyolysis treated?

What is the role of fluid resuscitation in the treatment of rhabdomyolysis?

What causes acute renal failure (ARF) in rhabdomyolysis?

What causes acute tubular necrosis (ATN) in rhabdomyolysis?

What are the risk factors for acute kidney injury in rhabdomyolysis?

How is acute kidney injury prevented in rhabdomyolysis?

How are electrolyte abnormalities treated in rhabdomyolysis?

When is dialysis indicated in the treatment of rhabdomyolysis?

What is the role of free-radical scavengers and antioxidants in the treatment of rhabdomyolysis?

What is included in the long-term outpatient treatment of rhabdomyolysis?

What is the role of surgery in the treatment of rhabdomyolysis?

Which dietary modifications are used in the treatment of rhabdomyolysis?

Which activity modifications are used in the treatment of rhabdomyolysis?

How is rhabdomyolysis prevented?

Which specialist consultations are beneficial to patients with rhabdomyolysis?

Medications

What is the role of medications in the treatment of rhabdomyolysis?

Which medications in the drug class Alkalinizing Agents are used in the treatment of Rhabdomyolysis?

Which medications in the drug class Beta2-Agonists are used in the treatment of Rhabdomyolysis?

Which medications in the drug class Antidotes, Other are used in the treatment of Rhabdomyolysis?

Which medications in the drug class Diuretics, Osmotic Agents are used in the treatment of Rhabdomyolysis?

Which medications in the drug class Diuretics, Loop are used in the treatment of Rhabdomyolysis?

Which medications in the drug class Volume Expanders are used in the treatment of Rhabdomyolysis?