Vasculitis and Thrombophlebitis Questions & Answers

Updated: Dec 10, 2018
  • Author: Nadia Jennifer Chiara Luca, MD; Chief Editor: Lawrence K Jung, MD  more...
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Questions & Answers

Overview

What is vasculitis?

What is the Chapel Hill classification of vasculitis?

What are the limitations of classifying vasculitis by vessel size?

What is the EULAR and PRES classification of vasculitis?

What are the classification criteria for large-vessel vasculitides?

What are the classification criteria for medium-vessel vasculitides?

What are the classification criteria for small-vessel vasculitides?

What are the classification criteria for Behcet disease?

What are the classification criteria for Anti-GBM antibody disease (Goodpasture syndrome)?

What is thrombophlebitis?

What is the pathophysiology of vasculitis?

What is the pathophysiology of giant cell-mediated vasculitis

What is the pathophysiology of necrotizing vasculitis?

What is the pathophysiology of antibody-mediated vasculitides?

What is the role of antibody deposition in the pathophysiology of vasculitis?

What is the US prevalence of vasculitis?

What are the sexual predilections of vasculitis?

Which age groups have the highest prevalence of vasculitis?

What is the global prevalence of vasculitis?

What is the mortality and morbidity associated with vasculitis?

What are the racial predilections of vasculitis?

Presentation

Which clinical history findings are characteristic of vasculitis?

Which clinical history findings are characteristic of Henoch-Schönlein purpura?

Which clinical history findings are characteristic of Kawasaki disease?

Which respiratory findings are characteristic of vasculitis?

Which cardiovascular findings are characteristic of vasculitis?

Which abdominal and genitourinary findings are characteristic of vasculitis?

Which musculoskeletal findings are characteristic of vasculitis?

Which neurologic findings are characteristic of vasculitis?

Which vital sign findings are characteristic of vasculitis?

Which head and neck findings are characteristic of vasculitis?

Which dermatologic findings are characteristic of vasculitis?

What causes vasculitis?

DDX

What are the differential diagnoses for Vasculitis and Thrombophlebitis?

Workup

What is the focus of the workup for vasculitis?

Which general lab findings are characteristic of vasculitis?

What is the role of organ specific lab tests in the workup of vasculitis?

What is the role of urine studies in the workup of vasculitis?

What is the role of lumbar puncture in the workup of vasculitis?

What is the role of autoantibody tests in the workup of vasculitis?

How is infection assessed in the workup of vasculitis?

Which lab tests are performed in the workup of antiphospholipid antibody syndrome?

How is pediatric antiphospholipid antibody syndrome diagnosed?

What is included in the workup of thrombophilia?

What is the role of in the workup of vasculitis?

What is the role of chest radiography in the workup of vasculitis?

What is the role of sinus CT scanning in the workup of vasculitis?

What is the role of a chest CT scan in the workup of vasculitis?

What is the role of echocardiography in the workup of vasculitis?

What is the role of brain imaging in the workup of vasculitis?

What is the role of angiography in the workup of vasculitis?

What is the role of ultrasonography in the workup of vasculitis?

What is the role of PET scanning in the workup of vasculitis?

What is the role of ECG in the workup of vasculitis?

When is NCS indicated in the workup of vasculitis?

When is electroencephalogram indicated in the workup of vasculitis?

When is bronchoscopy indicated in the workup of vasculitis?

What is the role of pulmonary function testing (PFT) in the workup of vasculitis?

What is the role of biopsy in the workup of vasculitis?

Which histologic findings are characteristic of vasculitis?

Treatment

How is vasculitis treated?

How is ANCA-associated vasculitis treated?

What is the role of induction therapy in the treatment of ANCA-associated vasculitis?

What is included in maintenance therapy for ANCA-associated vasculitis?

How is refractory or relapsing ANCA-associated vasculitis treated?

How is systemic polyarteritis nodosa treated?

How is cutaneous polyarteritis nodosa treated?

How is large vessel vasculitis treated?

How is primary CNS vasculitis treated?

How is thrombophlebitis treated?

What is the role of surgery in the treatment of vasculitis?

Which specialist consultations are beneficial to patients with vasculitis?

Which dietary modifications are used in the treatment of vasculitis?

Which activity modifications are used in the treatment of vasculitis?

Follow-up

What is included in the long-term monitoring of vasculitis?

When is patient transfer required for the treatment of vasculitis?

How is vasculitis prevented?

What are the possible complications of vasculitis?

What is the prognosis of vasculitis?

What is included in patient education about vasculitis?

Medications

Which medications in the drug class Antibiotics are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Anticoagulant are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Anti-B lymphocyte agent are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Tumor Necrosis Factor Inhibitor are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Immunosuppressant Agents are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Immunomodulators are used in the treatment of Vasculitis and Thrombophlebitis?

Which medications in the drug class Corticosteroids are used in the treatment of Vasculitis and Thrombophlebitis?