Ackee Fruit Toxicity Workup

Updated: Mar 28, 2022
  • Author: Dave A Holson, MD, MBBS, MPH; Chief Editor: Stephen L Thornton, MD  more...
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Laboratory Studies

In patients with suspected ackee fruit poisoning, immediately order a fingerstick glucose test; do not wait for the serum glucose result. Profound hypoglycemia with blood glucose levels as low as 3 mg/dL has been documented. [14]

Obtain a serum chemical test to exclude electrolyte abnormalities as a consequence of the intractable vomiting. Elevated ammonia levels have also been reported.

Liver function tests demonstrate increased hepatic transaminases.

Obtain a urinalysis. In ackee fruit poisoning, results show acidosis but no ketosis. 


Imaging Studies

Nonenhanced head CT scanning may be indicated for the exclusion of structural intracranial pathology in patients with altered mental status or new-onset seizures. Patients with hypoglycemia may present with a focal neurologic deficit. In other patients, head CT scan findings should be normal.


Histologic Findings

Liver biopsy reveals depleted glycogen stores. Postmortem examination reveals the absence of liver glycogen and the fatty metamorphosis of the liver, kidney, and other organs.