Salicylate Toxicity Questions & Answers

Updated: Feb 25, 2019
  • Author: Muhammad Waseem, MBBS, MS, FAAP, FACEP, FAHA; Chief Editor: Timothy E Corden, MD  more...
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Questions & Answers

Overview

What is salicylate toxicity?

What are phases of salicylate toxicity?

What is the antidote for salicylate toxicity?

What is the pathophysiology of salicylate toxicity?

What is the role of catabolism in the pathophysiology of salicylate toxicity?

What causes the respiratory system effects of salicylate toxicity?

What causes hypoglycemia in salicylate toxicity?

What causes dehydration in salicylate toxicity?

What causes the CNS effects of salicylate toxicity?

What causes the GI tract effects of salicylate toxicity?

What causes the hepatic effects of salicylate toxicity?

What causes the hematologic effects of salicylate toxicity?

What causes rhabdomyolysis in salicylate toxicity?

What is the prevalence of salicylate toxicity in the US?

Which age groups have the highest prevalence of salicylate toxicity?

What is the prognosis of salicylate toxicity?

What are the categories of salicylate toxicity?

What is included in patient education about salicylate toxicity?

Presentation

What is the focus of the clinical history to evaluate salicylate toxicity?

Which clinical history findings are characteristic of salicylate toxicity?

What are the pulmonary signs and symptoms of salicylate toxicity?

What are the auditory signs and symptoms of salicylate toxicity?

What are the cardiovascular signs and symptoms of salicylate toxicity?

What are the neurologic signs and symptoms of salicylate toxicity?

What are the GI signs and symptoms of salicylate toxicity?

What are genitourinary signs and symptoms of salicylate toxicity?

What are hematologic signs and symptoms of salicylate toxicity?

What are dermatologic signs and symptoms of salicylate toxicity?

What are electrolytic-associated signs and symptoms of salicylate toxicity?

DDX

What conditions should be considered in the differential diagnosis of salicylate toxicity?

What are the differential diagnoses for Salicylate Toxicity?

Workup

How is salicylate toxicity diagnosed?

Why is peak salicylate concentration monitored in patients with salicylate toxicity?

What is the role of serum electrolytes and renal function studies in the workup of salicylate toxicity?

What is the role of urinalysis in the workup of salicylate toxicity?

What is the role of chest radiograph in the workup of salicylate toxicity?

What is the role of imaging studies in the workup of salicylate toxicity?

Which studies may be useful in the workup of salicylate toxicity?

What is the correlation of toxicity with serum levels of salicylates?

What is the role of the Done nomogram in the workup of salicylate toxicity?

What is the role of bedside ferric chloride testing in the workup of salicylate toxicity?

What is the role of arterial blood gas in the workup of salicylate toxicity?

Treatment

How is salicylate toxicity treated?

What is included in follow-up care of salicylate toxicity?

Which specialist consultations are beneficial to patients with salicylate toxicity?

What are the guidelines on out-of-hospital triage care for salicylate toxicity?

When is endotracheal intubation indicated in the treatment of salicylate toxicity?

What is the initial emergency department (ED) treatment for salicylate toxicity?

What is the role of GI tract decontamination in the treatment of salicylate toxicity?

What is the role of urinary alkalization and enhanced excretion in the treatment of salicylate toxicity?

When is hemodialysis indicated in salicylate toxicity treatment?

What is the role of peritoneal dialysis in salicylate toxicity treatment?

What are the EXTRIP Workgroup recommendations for extracorporeal treatment of salicylate toxicity?

When is inpatient care indicated for salicylate toxicity treatment?

Medications

What is the role of medications in salicylate toxicity treatment?

Which medications in the drug class Urinary Alkalinizing Agents are used in the treatment of Salicylate Toxicity?

Which medications in the drug class Laxatives, Osmotic are used in the treatment of Salicylate Toxicity?

Which medications in the drug class Antidotes, Other are used in the treatment of Salicylate Toxicity?