Tricyclic Antidepressant Toxicity in Pediatrics Questions & Answers

Updated: Mar 18, 2020
  • Author: Derrick Lung, MD, MPH, FACEP, FACMT; Chief Editor: Stephen L Thornton, MD  more...
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Questions & Answers

Overview

What is the US FDA public health advisory for use of tricyclic antidepressants (TCAs) in pediatric populations?

Which tricyclic antidepressants (TCAs) are FDA approved for the treatment of major depressive disorder (MDD) in pediatric patients?

What are the most common uses of tricyclic antidepressants (TCAs) in pediatric patients?

What are the most commonly prescribed tricyclic antidepressants (TCAs) in pediatric patients?

What are the signs and symptoms of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the pathophysiology of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the prevalence of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the prognosis of tricyclic antidepressant (TCA) toxicity in pediatric patients?

Presentation

Which clinical history findings are characteristic of tricyclic antidepressant (TCA) toxicity in pediatric patients?

Which physical findings are characteristic of tricyclic antidepressant (TCA) toxicity in pediatric patients?

DDX

What are the differential diagnoses for Tricyclic Antidepressant Toxicity in Pediatrics?

Workup

What is the role of lab tests in the workup of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the role of serum cyclic antidepressant measurement in the workup of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the role of imaging in the workup of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the role of ECG in the workup of tricyclic antidepressant (TCA) toxicity in pediatric patients?

Treatment

How is tricyclic antidepressant (TCA) toxicity treated in pediatric patients?

What is the role of decontamination in the treatment of tricyclic antidepressant (TCA) toxicity in pediatric patients?

What is the role of lipid emulsion therapy in the treatment of tricyclic antidepressant (TCA) toxicity in pediatric patients?

How are seizures treated in pediatric patients with tricyclic antidepressant (TCA) toxicity?

How are cardiovascular complications treated in pediatric patients with tricyclic antidepressant (TCA) toxicity?

How is serotonin syndrome treated in pediatric patients with tricyclic antidepressant (TCA) toxicity?

Which specialist consultations are beneficial to pediatric patients with tricyclic antidepressant (TCA) toxicity?

How is pediatric tricyclic antidepressant (TCA) toxicity prevented?

Medications

What is the role of medications in the treatment of in pediatric tricyclic antidepressant (TCA) toxicity?

Which medications in the drug class Anticonvulsant agents are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?

Which medications in the drug class Antiarrhythmic agents are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?

Which medications in the drug class Inotropic agents are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?

Which medications in the drug class Vasopressors are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?

Which medications in the drug class Alkalinizing agents are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?

Which medications in the drug class Decontaminants are used in the treatment of Tricyclic Antidepressant Toxicity in Pediatrics?