PCP Toxicity Follow-up

Updated: Feb 01, 2017
  • Author: Stephan Brenner, MD, MPH; Chief Editor: Timothy E Corden, MD  more...
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Follow-up

Further Outpatient Care

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  • Refer the patient for drug rehabilitation.
  • Because of its long-lasting side effect of inducing or unmasking psychopathologic symptoms, continued outpatient therapy including prolonged use of tranquilizers may be necessary for patients after PCP intoxication. [22]
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Further Inpatient Care

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  • Admit the patient who has ingested phenylcyclohexyl piperidine (PCP), also known as phencyclidine, to an ICU if evidence of hyperthermia, seizure activity, or rhabdomyolysis is present.
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Complications

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  • The usual street dose of PCP is 1-6 mg and results in mild intoxication. Larger ingestions (6-10 mg) can cause toxic psychoses and signs of sympathetic hyperactivity, including hypertension, rigidity, hyperthermia, tachycardia, and seizure. Very large doses (≥ 200 mg) can result in death. Deaths from the direct effects of PCP intoxication are related to hyperthermia, renal failure, DIC, or rhabdomyolysis.
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Patient Education

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