Differences (Disorders) of Sex Development (DSDs) Medication

Updated: Nov 30, 2021
  • Author: Osama Al-Omar, MD, MBA, FACS, FEBU; Chief Editor: Marc Cendron, MD  more...
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Medication

Medication Summary

Medications used in disorders of sex development (DSDs) depend on the underlying cause.

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Glucocorticoids

Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. They modify the body's immune response to diverse stimuli. Children with congenital adrenal hyperplasia (CAH) require corticosteroid replacement for survival. Replacement also reduces the production of corticotropin and, therefore, the overproduction of androgens.

Hydrocortisone (Hydrocortone, Cortef)

Drug of choice because of mineralocorticoid activity and glucocorticoid effects.

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