Piriformis Injection Medication

Updated: Apr 27, 2022
  • Author: Mary Louise Caire, MD; Chief Editor: Erik D Schraga, MD  more...
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Medication

Medication Summary

The goal of pharmacotherapy is to provide local anesthesia, both superficial and deep, prior and throughout the procedure.

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Local Anesthetics

Class Summary

Local anesthetic agents are used to increase patient comfort during the procedure.

Lidocaine (Xylocaine)

Lidocaine is an amide local anesthetic. This agent inhibits depolarization of type C sensory neurons by blocking sodium channels. It is provided by means of local infiltration of 1% lidocaine buffered with sodium bicarbonate.

Bupivacaine (Marcaine, Sensorcaine)

Bupivacaine 0.25% may be used in combination with lidocaine plus epinephrine (50:50 mixture). It decreases permeability to sodium ions in neuronal membranes. This results in the inhibition of depolarization, blocking the transmission of nerve impulses.

Ropivacaine (Naropin)

Ropivacaine decreases permeability to sodium ions in neuronal membranes. This results in the inhibition of depolarization, blocking the transmission of nerve impulses. This agent is an option for longer postoperative analgesia. The onset is delayed from 5 minutes to about 20 minutes.

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