Common Variable Immunodeficiency Questions & Answers

Updated: Mar 17, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is common variable immunodeficiency (CVID)?

What are the complications of common variable immunodeficiency (CVID)?

What are the dermatologic symptoms of common variable immunodeficiency (CVID)?

What is the clinical presentation of sarcoidosis-like common variable immunodeficiency (CVID)?

What is the role of lab testing in the workup of common variable immunodeficiency (CVID)?

What is the role of imaging studies in the diagnosis of common variable immunodeficiency (CVID)?

Which histologic findings are characteristic of common variable immunodeficiency (CVID)?

Which clinical procedures are performed in the diagnosis of common variable immunodeficiency (CVID)?

How is common variable immunodeficiency (CVID) treated?

What is the role of surgery in the treatment of common variable immunodeficiency (CVID)?

What is common variable immunodeficiency (CVID)?

What is the pathophysiology of common variable immunodeficiency (CVID)?

What is the role of humoral responses in the pathophysiology of common variable immunodeficiency (CVID)?

Which changes in the cell-mediated response can lead to the development of common variable immunodeficiency (CVID)?

What causes common variable immunodeficiency (CVID)?

What is the prevalence of common variable immunodeficiency (CVID)?

Which patient groups have the highest prevalence of common variable immunodeficiency (CVID)?

What is the prognosis of common variable immunodeficiency (CVID)?

What should be included in patient education about common variable immunodeficiency (CVID)?

Presentation

What are the phenotypes of common variable immunodeficiency (CVID)?

Which clinical history findings are characteristic of common variable immunodeficiency (CVID)?

Which physical findings are characteristic of common variable immunodeficiency (CVID)?

Which recurrent infections may be present in common variable immunodeficiency (CVID)?

What are the autoimmune complications of common variable immunodeficiency (CVID)?

Which malignancies may be present in common variable immunodeficiency (CVID)?

What are the dermatologic manifestations of common variable immunodeficiency (CVID)?

What are possible complications of common variable immunodeficiency (CVID)?

What causes death in patients with common variable immunodeficiency (CVID)?

DDX

Which conditions should be included in the differential diagnosis of common variable immunodeficiency (CVID)?

What are the differential diagnoses for Common Variable Immunodeficiency?

Workup

How is common variable immunodeficiency (CVID) diagnosed?

What is the role of lab testing in the diagnosis of common variable immunodeficiency (CVID)?

What is the role of imaging studies in the workup of common variable immunodeficiency (CVID)?

What is the role of pulmonary function testing in the workup of common variable immunodeficiency (CVID)?

Which clinical procedures are performed in the workup of common variable immunodeficiency (CVID)?

Which histologic findings are characteristic of common variable immunodeficiency (CVID)?

How is malignancy in common variable immunodeficiency (CVID) staged?

Treatment

What is the role of Ig replacement therapy in the treatment of common variable immunodeficiency (CVID)?

What is the role of cyclosporin A in the treatment of common variable immunodeficiency (CVID)?

What is the role of antimicrobial therapy in the treatment of common variable immunodeficiency (CVID)?

How does the organ system involved affect the treatment of common variable immunodeficiency (CVID)?

How is common variable immunodeficiency (CVID) treated during pregnancy?

What is the role of quality-of-life assessment in the treatment of common variable immunodeficiency (CVID)?

When is inpatient care indicated in the treatment of common variable immunodeficiency (CVID)?

What is the role of surgery in the treatment of common variable immunodeficiency (CVID)?

Which specialist consultations are beneficial for patients with common variable immunodeficiency (CVID)?

What is the role of vaccines in the management of common variable immunodeficiency (CVID)?

What is included in long-term monitoring of patients with common variable immunodeficiency (CVID)?

Medications

What is the goal of drug treatment for common variable immunodeficiency (CVID)?

Which medications in the drug class Immunoglobulins are used in the treatment of Common Variable Immunodeficiency?