Acrodermatitis Chronica Atrophicans Treatment & Management

Updated: Dec 14, 2022
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Long-Term Monitoring

Initially, follow-up care should be performed every 3-6 months; later, it may be performed once a year. Physical examination for signs and symptoms of cutaneous and extracutaneous manifestations of Lyme borreliosis is important. In most ACA patients who have received antibiotic therapy, quantitative serologic tests show IgG antibody titers that either do not change or decline only to a certain extent.

Despite the persistence of IgG antibody response in late Lyme borreliosis (serologic scar), similar to that observed in syphilis cases, the authors do serologic follow-up testing according to the recommendation for late syphilis. A sudden increase in antibody titer can point to the activation of infection and precede a clinical recurrence of the disease.