Trichomycosis Axillaris Medication

Updated: Nov 08, 2021
  • Author: Nicholas V Nguyen, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication Summary

Treatment of trichomycosis axillaris can be achieved simply by shaving the affected hair. Application of a benzoyl peroxide gel or wash is effective and prevents recurrence. Antiperspirants also provide an effective means of therapy and prevention. Fusidic acid may be helpful in treating trichomycosis axillaris.


Topical skin products

Class Summary

Topical skin products are useful in the treatment of irritation caused by oxidized bacterial proteins in sebaceous follicles.

Benzoyl peroxide (Benzac, Benoxyl, Clearasil)

Free-radical oxygen is released upon administration and oxidizes bacterial proteins in sebaceous follicles, decreasing the number of anaerobic bacteria and irritating free fatty acids. Benzoyl peroxide is converted on the skin into benzoic acid, which has an antibacterial activity, as well as keratolytic and comedolytic effects. Benzoyl peroxide is available in 2.5%, 5%, and 10% gels, lotions, creams, or washes.



Class Summary

Antiperspirants interfere with normal secretions of sweat glands, drying the affected area. A variety of antiperspirants are available over the counter; prescription-strength topical desiccants listed.

Aluminum chloride hexahydrate (Drysol)

Aluminum chloride hexahydrate is an astringent agent used in the management of hyperhidrosis. It is a solution of 20% aluminum chloride in ethyl alcohol.


Topical antibiotics

Class Summary

Topical antibiotics work by inhibiting the growth of microorganisms that cause trichomycosis axillaris.

Clindamycin solution (Cleocin T)

Clindamycin solution is a lincosamide for the treatment of serious skin and soft tissue staphylococcal infections. It inhibits bacterial growth, possibly by blocking dissociation of peptidyl t-RNA from ribosomes causing RNA-dependent protein synthesis to arrest.

Upon application to the skin, drug is converted to the active component, which inhibits the microorganism. It is available as a topical solution, lotion, or gel for external use. The solution contains the equivalent of 10 mg/mL of clindamycin.

Erythromycin topical (T-Stat)

Erythromycin inhibits bacterial growth, possibly by blocking dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest. It is used for the treatment of staphylococcal and streptococcal infections. Topical erythromycin is available as a 2% topical solution.