Acrokeratosis Verruciformis of Hopf Treatment & Management

Updated: May 11, 2018
  • Author: Sarah Sweeney Pinney, MD; Chief Editor: William D James, MD  more...
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Treatment

Medical Care

The only effective treatment is superficial ablation. Treatment is not generally recommended, but medical and surgical treatments have been tried. [29] Applications of retinoic acid have been helpful in some individuals. Oral vitamin A derivatives have also been reported to have some success. [19, 29] Destruction of the lesions with cryotherapy or laser, especially destructive lasers such as a carbon dioxide or Nd:YAG laser, may be used. Untreated lesions persist and become more noticeable after prolonged sun exposure because of darkening.

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Complications

Transformation to squamous cell carcinoma of the skin has been reported in two cases. [18]

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