Pilomatrixoma Treatment & Management

Updated: Oct 13, 2020
  • Author: Jaggi Rao, MD, FRCPC; Chief Editor: Dirk M Elston, MD  more...
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Medical Care

Medical treatment has yet to be successful. [25]


Surgical Care

Spontaneous regression has never been observed. The treatment of choice is surgical excision. [56, 57] Lesions are mostly poorly delineated, but encapsulated forms have been observed; these are less likely to recur because complete resection is easier. Incomplete resections have been followed by local recurrence; wide resection margins (1-2 cm) have been recommended to minimize the risk of recurrence. Recurrence rates are relatively low (1.4%). [25]

Secondary lesions after surgery are rare; this risk decreases progressively with age. In addition, Mohs micrographic surgery has been used in an effort to ensure better margin control. For patients with numerous pilomatrixomas, all lesions should be excised and the presence of associated or familial conditions should be considered. [25]


Long-Term Monitoring

Patients should be monitored to ensure lesions do not recur after surgical excision.