Medical Care

No medical care is required.

Surgical Care

Removal of the lesion by performing a punch biopsy or an excisional biopsy is an effective therapy for these benign lesions.

Diet

This benign process is unrelated to dietary influences.

Complications

The only complications associated with warty dyskeratoma (WD) are those associated with the minor surgical procedures required for the biopsy or the removal of these benign lesions.

Medication

Szymanski FJ. Warty dyskeratoma; a benign cutaneous tumor resembling Darier's disease microscopically. Arch Derm. 1957 Apr. 75(4):567-72. [QxMD MEDLINE Link].
Allon I, Buchner A. Warty dyskeratoma/focal acantholytic dyskeratosis--an update on a rare oral lesion. J Oral Pathol Med. Mar 2012. 41(3):261-7. [QxMD MEDLINE Link].
Azuma Y, Matsukawa A. Warty dyskeratoma with multiple lesions. J Dermatol. 1993 Jun. 20(6):374-7. [QxMD MEDLINE Link].
Phelps PO, Hinshaw MA, Potter HD. Warty Dyskeratoma of the Eyelid. Ophthalmology. 2015 Jul. 122 (7):1282. [QxMD MEDLINE Link].
Duray PH, Merino MJ, Axiotis C. Warty dyskeratoma of the vulva. Int J Gynecol Pathol. 1983. 2(3):286-93. [QxMD MEDLINE Link].
Koç M, Kavala M, Kocatürk E, Mete O, Can B, Zindanci I, et al. Multiple warty dyskeratomas on the scalp. Dermatol Online J. 2009 Feb. 15(2):8. [QxMD MEDLINE Link].
Heymann WR. Warty dyskeratoma appearing in a patient with Darier's disease. Int J Dermatol. 1988 Sep. 27(7):521-2. [QxMD MEDLINE Link].
Allon I, Buchner A. Warty dyskeratoma/focal acantholytic dyskeratosis - an update on a rare oral lesion. J Oral Pathol Med. 2011 Sep 21. [QxMD MEDLINE Link].
Jang EJ, Lee JY, Kim MK, Yoon TY. Warty dyskeratoma involving two adjoining follicles. Ann Dermatol. 2011 Feb. 23(1):98-100. [QxMD MEDLINE Link]. [Full Text].
Savignac M, Edir A, Simon M, Hovnanian A. Darier disease : a disease model of impaired calcium homeostasis in the skin. Biochim Biophys Acta. 2011 May. 1813(5):1111-7. [QxMD MEDLINE Link].
Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L. Warty dyskeratoma--"follicular dyskeratoma": analysis of clinicopathologic features of a distinctive follicular adnexal neoplasm. J Am Acad Dermatol. 2002 Sep. 47(3):423-8. [QxMD MEDLINE Link].
Szymanski FJ. Warty dyskeratoma; a benign cutaneous tumor resembling Darier's disease microscopically. AMA Arch Derm. 1957 Apr. 75(4):567-72. [QxMD MEDLINE Link].
Ghasemi Basir HR, Alirezaei P, Ebrahimi B, Khanali S. Oral warty dyskeratoma: An unusual presentation. Dermatol Reports. 2020 Jun 25. 12 (1):8236. [QxMD MEDLINE Link].
Zhao Q, Zhou H, Geng S. Multiple warty dyskeratoma on the scalp. An Bras Dermatol. 2019 Sep - Oct. 94 (5):630-631. [QxMD MEDLINE Link].
Baran R, Perrin C. Focal subungual warty dyskeratoma. Dermatology. 1997. 195(3):278-80. [QxMD MEDLINE Link].
Cohen PR. Longitudinal erythronychia: individual or multiple linear red bands of the nail plate: a review of clinical features and associated conditions. Am J Clin Dermatol. 2011 Aug 1. 12 (4):217-31. [QxMD MEDLINE Link].

Media Gallery

Absence of sarco/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) staining by immunohistochemistry within a warty dyskeratoma (right side of image), in contrast to the unaffected epidermis (left side of image). Photomicrograph courtesy of James E. Fitzpatrick, MD.
Warty dyskeratoma. An endo-exophytic squamous proliferation of cytologically benign, acantholytic, and dyskeratotic keratinocytes.
Villi lined by acantholytic keratinocytes, some of which are dyskeratotic (corps ronds and corps grains).

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Author

Molly Ann Allen Hinshaw, MD Associate Professor, Department of Dermatology, University of Wisconsin School of Medicine and Public Health

Molly Ann Allen Hinshaw, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Dermatology Foundation, Wisconsin Dermatological Society, Women's Dermatologic Society

Disclosure: Have a 5% or greater equity interest in: Accure Medical, I founded this company with two partners so have 33% interest in the company. We have spent our personal funds to start the company, have no products, and no income yet.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD Herman Beerman Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, Pennsylvania Academy of Dermatology

Disclosure: Received royalty from Lippincott Williams Wilkins for textbook editor.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Timothy McCalmont, MD Director, UCSF Dermatopathology Service, Professor of Clinical Pathology and Dermatology, Departments of Pathology and Dermatology, University of California at San Francisco; Editor-in-Chief, Journal of Cutaneous Pathology

Timothy McCalmont, MD is a member of the following medical societies: Alpha Omega Alpha, American Medical Association, American Society of Dermatopathology, California Medical Association, College of American Pathologists, United States and Canadian Academy of Pathology

Disclosure: Received consulting fee from Apsara for independent contractor.

Warty Dyskeratoma Treatment & Management

Medical Care

Surgical Care

Diet

Complications

References

Tables

Contributor Information and Disclosures

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