Updated: May 31, 2022
  • Author: Michael S Howard, MD; Chief Editor: Dirk M Elston, MD  more...
  • Print

Practice Essentials

Trichofolliculoma represents an uncommon hamartoma of hair follicle tissue, typically occurring on the face of adults. [1]  Notably, trichofolliculomas have been reported on the eyelids, auricle, and external auditory canal. [2, 3, 4]

Clinical appearance of trichofolliculoma. Clinical appearance of trichofolliculoma.

The prognosis is excellent, and therapy is usually directed toward cosmetic improvement.


Although the precise etiology of trichofolliculoma is uncertain, these tumors are not associated with systemic disease or other skin disorders. Trichofolliculomas are believed to represent abortive differentiation of pluripotent skin cells toward hair follicles.


The prognosis is excellent. Although reports exist of recurrence at the primary site, these events are rare. Trichofolliculomas are associated with minimal clinical morbidity; no confirmed cases of malignant transformation or clinical mortality are reported in the literature.

History and physical examination

Patients typically present with a single, flesh-colored or whitish nodule or papule of varying duration, typically on the face (most frequently around the nose).

Classic trichofolliculomas have a central pore or black dot, possibly draining a sebaceouslike material. A tuft of white hair may be present emerging from the central pore.


Usually, these tumors develop spontaneously. Rarely, a prior history of trauma at the tumor site is obtained.


See Workup.


Simple surgical excision is typically curative.



Trichofolliculoma represents an uncommon clinical entity. In reported cases, trichofolliculomas demonstrate no definitive racial predilection.

No definitive sexual predilection is observed in reported cases, although sporadic reports indicate a probable male preponderance. [5]

From published reports, trichofolliculoma appears to primarily be a tumor of adults; however, at least 2 cases of congenital trichofolliculoma have been reported. [6, 7]