Dermatologic Manifestations of Peyronie Disease Clinical Presentation

1. Devine CJ Jr, Somers KD, Jordan SG, Schlossberg SM. Proposal: trauma as the cause of the Peyronie's lesion. J Urol. 1997 Jan. 157(1):285-90. [QxMD MEDLINE Link].

2. Lucattelli M, Lunghi B, Fineschi S, et al. A new mouse model of Peyronie's disease: an increased expression of hypoxia-inducible factor-1 target genes during the development of penile changes. Int J Biochem Cell Biol. 2008. 40(11):2638-48. [QxMD MEDLINE Link].

3. Nachtsheim DA, Rearden A. Peyronie's disease is associated with an HLA class II antigen, HLA-DQ5, implying an autoimmune etiology. J Urol. 1996 Oct. 156(4):1330-4. [QxMD MEDLINE Link].

4. Nyberg LM Jr, Bias WB, Hochberg MC, Walsh PC. Identification of an inherited form of Peyronie's disease with autosomal dominant inheritance and association with Dupuytren's contracture and histocompatibility B7 cross-reacting antigens. J Urol. 1982 Jul. 128(1):48-51. [QxMD MEDLINE Link].

5. Gualdieri L, Valentini G, Lupoli S, Giordano M. Peyronie's disease in systemic sclerosis. Report of two cases. J Rheumatol. 1988 Feb. 15(2):380-1. [QxMD MEDLINE Link].

6. Stewart S, Malto M, Sandberg L, Colburn KK. Increased serum levels of anti-elastin antibodies in patients with Peyronie's disease. J Urol. 1994 Jul. 152(1):105-6. [QxMD MEDLINE Link].

7. Casabé A, Bechara A, Cheliz G, De Bonis W, Rey H. Risk factors of Peyronie's disease. What does our clinical experience show?. J Sex Med. 2011 Feb. 8(2):518-23. [QxMD MEDLINE Link].

8. Hricak H, Marotti M, Gilbert TJ, et al. Normal penile anatomy and abnormal penile conditions: evaluation with MR imaging. Radiology. 1988 Dec. 169(3):683-90. [QxMD MEDLINE Link].

9. Wang HJ, Guan J, Lin JH, Pan BT, Deng CH, Guo Y. [Diagnostic value of high-field MRI for Peyronie's disease]. Zhonghua Nan Ke Xue. 2016 Sep. 22 (9):787-791. [QxMD MEDLINE Link].

10. Erdogru T, Boz A, Koksal T, et al. Penile scintigraphy with 99mTc-human immunoglobulin G: a novel method for distinguishing the unstable and stable phases of Peyronie's disease. BJU Int. 2002 Nov. 90(7):703-6. [QxMD MEDLINE Link].

11. Waldhauser M, Schr. P. Efficiency and side effects of prostaglandin E1 in the treatment of erectile dysfunction. J Urol. 1988 Sep. 140(3):525-7. [QxMD MEDLINE Link].

12. Gelbard M, Goldstein I, Hellstrom WJ, McMahon CG, Smith T, Tursi J, et al. Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies. J Urol. 2013 Jul. 190(1):199-207. [QxMD MEDLINE Link].

13. Safarinejad MR, Asgari MA, Hosseini SY, Dadkhah F. A double-blind placebo-controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie's disease. BJU Int. 2009 Oct 26. [QxMD MEDLINE Link].

14. Biagiotti G, Cavallini G. Acetyl-L-carnitine vs tamoxifen in the oral therapy of Peyronie's disease: a preliminary report. BJU Int. 2001 Jul. 88(1):63-7. [QxMD MEDLINE Link].

15. Di Stasi SM, Giannantoni A, Stephen RL, et al. A prospective, randomized study using transdermal electromotive administration of verapamil and dexamethasone for Peyronie's disease. J Urol. 2004 Apr. 171(4):1605-8. [QxMD MEDLINE Link].

16. Levine LA, Merrick PF, Lee RC. Intralesional verapamil injection for the treatment of Peyronie's disease. J Urol. 1994 Jun. 151(6):1522-4. [QxMD MEDLINE Link].

17. Levine LA, Goldman KE, Greenfield JM. Experience with intraplaque injection of verapamil for Peyronie's disease. J Urol. 2002 Aug. 168(2):621-5; discussion 625-6. [QxMD MEDLINE Link].

18. Ahuja S, Bivalacqua TJ, Case J, Vincent M, Sikka SC, Hellstrom WJ. A pilot study demonstrating clinical benefit from intralesional interferon alpha 2B in the treatment of Peyronie's disease. J Androl. 1999 Jul-Aug. 20(4):444-8. [QxMD MEDLINE Link].

19. Dang G, Matern R, Bivalacqua TJ, Sikka S, Hellstrom WJ. Intralesional interferon-alpha-2B injections for the treatment of Peyronie's disease. South Med J. 2004 Jan. 97(1):42-6. [QxMD MEDLINE Link].

20. Polat O, Gul O, Ozbey I, Ozdikici M, Bayraktar Y. Peyronie's disease: intralesional treatment with interferon alpha-2A and evaluation of the results by magnetic resonance imaging. Int Urol Nephrol. 1997. 29(4):465-71. [QxMD MEDLINE Link].

21. Montorsi F, Salonia A, Guazzoni G, et al. Transdermal electromotive multi-drug administration for Peyronie's disease: preliminary results. J Androl. 2000 Jan-Feb. 21(1):85-90. [QxMD MEDLINE Link].

22. Morgan RJ, Pryor JP. Procarbazine (Natulan) in the treatment of Peyronie's disease. Br J Urol. 1978 Apr. 50(2):111-3. [QxMD MEDLINE Link].

23. Oosterlinck W, Renders G. Treatment of Peyronie's disease with procarbazine. Br J Urol. 1975 Apr. 47(2):219-20. [QxMD MEDLINE Link].

24. Hauck EW, Altinkilic BM, Ludwig M, et al. Extracorporal shock wave therapy in the treatment of Peyronie's disease. First results of a case-controlled approach. Eur Urol. 2000 Dec. 38(6):663-9;discussion 670. [QxMD MEDLINE Link].

25. Husain J, Lynn NN, Jones DK, Collins GN, O'Reilly PH. Extracorporeal shock wave therapy in the management of Peyronie's disease: initial experience. BJU Int. 2000 Sep. 86(4):466-8. [QxMD MEDLINE Link].

26. Incrocci L, Hop WC, Seegenschmiedt HM. Radiotherapy for Peyronie's Disease: a European survey. Acta Oncol. 2008. 47(6):1110-2. [QxMD MEDLINE Link].

27. Furlow WL, Swenson HE Jr, Lee RE. Peyronie's disease: a study of its natural history and treatment with orthovoltage radiotherapy. J Urol. 1975 Jul. 114(1):69-71. [QxMD MEDLINE Link].

28. Yafi FA, Pinsky MR, Stewart C, Sangkum P, Ates E, Trost LW, et al. The Effect of Duration of Penile Traction Therapy in Patients Undergoing Intralesional Injection Therapy for Peyronie's Disease. J Urol. 2015 Sep. 194 (3):754-8. [QxMD MEDLINE Link].

29. Abern MR, Larsen S, Levine LA. Combination of penile traction, intralesional verapamil, and oral therapies for Peyronie's disease. J Sex Med. 2012 Jan. 9 (1):288-95. [QxMD MEDLINE Link].

30. Ziegelmann MJ, Viers BR, Montgomery BD, Avant RA, Savage JB, Trost LW. Clinical Experience With Penile Traction Therapy Among Men Undergoing Collagenase Clostridium histolyticum for Peyronie Disease. Urology. 2017 Jun. 104:102-109. [QxMD MEDLINE Link].

31. [Guideline] Nehra A, Alterowitz R, Culkin DJ, Faraday MM, Hakim LS, Heidelbaugh JJ, et al. Peyronie's Disease: AUA Guideline. J Urol. 2015 Sep. 194 (3):745-53. [QxMD MEDLINE Link].

32. Trussell JC, Brien JC. Straightening out Peyronie's: a medical and surgical approach to the patient. Can J Urol. 2008 Jun. 15(3):4047-55. [QxMD MEDLINE Link].

33. Chung E. Penile Reconstructive Surgery in Peyronie Disease: Challenges in Restoring Normal Penis Size, Shape, and Function. World J Mens Health. 2018 Mar 29. [QxMD MEDLINE Link]. [Full Text].

34. Devine CJ Jr, Horton CE. Surgical treatment of Peyronie's disease with a dermal graff. J Urol. 1974 Jan. 111(1):44-9. [QxMD MEDLINE Link].

35. Gangai MP, Rivera LR, Spence CR. Peyronie's plaque: excision and graft versus incision and stent. J Urol. 1982 Jan. 127(1):55-6. [QxMD MEDLINE Link].

36. Wild RM, Devine CJ Jr, Horton CE. Dermal graft repair of Peyronie's disease: survey of 50 patients. J Urol. 1979 Jan. 121(1):47-50. [QxMD MEDLINE Link].

37. Imbeault A, Bernard G, Ouellet G, Bouhout S, Carrier S, Bolduc S. Surgical option for the correction of Peyronie's disease: an autologous tissue-engineered endothelialized graft. J Sex Med. 2011 Nov. 8(11):3227-35. [QxMD MEDLINE Link].

38. Knoll LD, Furlow WL, Benson RC Jr. Management of Peyronie disease by implantation of inflatable penile prosthesis. Urology. 1990 Nov. 36(5):406-9. [QxMD MEDLINE Link].

39. Yafi FA, Sangkum P, McCaslin IR, Hellstrom WJ. Strategies for penile prosthesis placement in Peyronie's disease and corporal fibrosis. Curr Urol Rep. 2015 Apr. 16 (4):21. [QxMD MEDLINE Link].

40. Fournier GR Jr, Lue TF, Tanagho EA. Peyronie's plaque: surgical treatment with the carbon dioxide laser and a deep dorsal vein patch graft. J Urol. 1993 May. 149(5 Pt 2):1321-5. [QxMD MEDLINE Link].

41. Zarafonetis CJ, Horrax TM. Treatment of Peyronie's disease with potassium para-aminobenzoate (potaba). J Urol. 1959 Jun. 81(6):770-2. [QxMD MEDLINE Link].

42. Akkus E, Carrier S, Rehman J, Breza J, Kadioglu A, Lue TF. Is colchicine effective in Peyronie's disease? A pilot study. Urology. 1994 Aug. 44(2):291-5. [QxMD MEDLINE Link].

43. Ralph DJ, Brooks MD, Bottazzo GF, Pryor JP. The treatment of Peyronie's disease with tamoxifen. Br J Urol. 1992 Dec. 70(6):648-51. [QxMD MEDLINE Link].

Anne Elizabeth Laumann, MBChB, MRCP(UK), FAAD Professor Emerita of Dermatology, Northwestern University, The Feinberg School of Medicine

Anne Elizabeth Laumann, MBChB, MRCP(UK), FAAD is a member of the following medical societies: American Academy of Dermatology, American Academy of Dermatology Association, American College of Wound Healing and Tissue Repair, American Dermato-Epidemiology Network, Association for Psychoneurocutaneous Medicine of North America, Association of Professors of Dermatology, British Association of Dermatologists, Chicago Dermatological Society, Chicago Medical Society, Dermatology Foundation, European Society of Tattoo and Pigment Research, Illinois Dermatological Society, Illinois State Medical Society, Institute of Medicine of Chicago, Lupus Foundation of America, Illinois Chapter, Medical Dermatology Society, National Psoriasis Foundation, National Vitiligo Foundation, North American Rheumatologic Dermatology Society, Rheumatologic Dermatology Society, Scleroderma Foundation, Society for Investigative Dermatology, The Global Fibrosis Foundation, Women's Dermatologic Society

Disclosure: Nothing to disclose.

Joseph J Pariser, MD Assistant Professor of Urology, Department of Urology, University of Minnesota Medical School

Disclosure: Nothing to disclose.

Victoria Godinez-Puig, MD Resident Physician, Department of Dermatology, Northwestern University, The Feinberg School of Medicine

Victoria Godinez-Puig, MD is a member of the following medical societies: Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Gregory Bales, MD Associate Professor, Department of Surgery, Section of Urology, University of Chicago

Gregory Bales, MD is a member of the following medical societies: American Urological Association

Disclosure: Nothing to disclose.

David F Butler, MD Former Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Military Dermatologists, Phi Beta Kappa, Texas Dermatological Society

Disclosure: Nothing to disclose.

Jeffrey P Callen, MD Professor of Medicine (Dermatology), Chief, Division of Dermatology, University of Louisville School of Medicine

Jeffrey P Callen, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, American College of Rheumatology

Disclosure: Received income in an amount equal to or greater than $250 from: Biogen US (Adjudicator for study entry cutaneous lupus erythematosus); Priovant (Adjudicator for entry into a dermatomyositis study); IQVIA (Serono - adjudicator for a study of cutaneous LE) <br/>Received honoraria from UpToDate for author/editor; Received royalty from Elsevier for book author/editor; Received dividends from trust accounts, but I do not control these accounts, and have directed our managers to divest pharmaceutical stocks as is fiscally prudent from Stock holdings in various trust accounts include some pharmaceutical companies and device makers for these trust accounts for: Stocks held in various trust accounts: Allergen; Amgen; Pfizer; 3M; Johnson and Johnson; Merck; Abbott Laboratories; AbbVie; Procter and Gamble;; Celgene; Gilead; CVS; Walgreens; Bristol-Myers Squibb.

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Jay W Zimmerman, MD, FAAD Consulting Physician, Berman Skin Institute, Palo Alto

Jay W Zimmerman, MD, FAAD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, California Medical Association

Disclosure: Received consulting fee from Allergan for consulting; Received consulting fee from Centocor for consulting; Received consulting fee from Galderma for consulting; Received consulting fee from Coria Labs for consulting.

• Print this section
• Print the entire contents of
• Print the entire contents of article