Pemphigoid Gestationis Differential Diagnoses

Updated: Mar 25, 2022
  • Author: Victor A Teran, MD; Chief Editor: William D James, MD  more...
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Diagnostic Considerations

Pemphigoid gestationis shares common features with other dermatoses of pregnancy; these similarities make diagnosis more difficult. The criteria for diagnosis include a compatible clinical picture, the observation of a subepidermal blistering disease upon histopathologic evaluation, and a linear band of C3 at the epidermodermal junction detected with direct immunofluorescence (DIF) testing. An accurate diagnosis is important before therapy is initiated.

Differential Diagnoses