IgA Pemphigus Differential Diagnoses

Updated: Apr 18, 2017
  • Author: Blanca Anais Estupiñan; Chief Editor: Dirk M Elston, MD  more...
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DDx

Diagnostic Considerations

Disorders presenting with grouped pustules or vesicular lesions may resemble IgA pemphigus. These include bullous impetigo, pustular psoriasis, linear IgA bullous dermatosis, and dermatitis herpetiformis. Classic subcorneal pustular dermatosis (Sneddon-Wilkinson) may present clinically and histologically identical to IgA pemphigus, but direct immunofluorescence yields a negative result. Although there is much clinical overlap owing to the diverse presentation of IgA pemphigus, pemphigus foliaceus tends to form fragile vesicles or bullae concentrating mostly on the face, scalp, and trunk on the chest and upper back. Additional differential diagnoses to consider are listed below.

Differential Diagnoses