Morphea Questions & Answers

Updated: May 21, 2018
  • Author: Jennifer V Nguyen, MD; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is morphea?

What is the pathophysiology of morphea?

What causes morphea?

What is the incidence of morphea in the US?

What are the racial predilections for morphea?

How does the incidence of morphea vary by sex?

Which age groups are at highest risk for morphea?

What is the prognosis of morphea?

What is the mortality and morbidity of morphea?

Presentation

What are the signs and symptoms of morphea?

Which physical findings are characteristic of morphea?

What is circumscribed morphea?

How are the lesions of the superficial variant of circumscribed morphea characterized?

How are the lesions of the deep variant of circumscribed morphea characterized?

How are guttate morphea lesions characterized?

How are Keloidal (nodular) morphea lesions characterized?

How are atrophoderma of Pasini and Pierini lesions characterized?

How are bullous morphea lesions characterized?

How is generalized morphea defined?

What are the clinical presentations of linear morphea variants?

What is pansclerotic morphea?

What is mixed morphea?

What are the physical findings characteristic of morphea?

What are complications of morphea?

DDX

Which conditions should be included in the differential diagnoses of morphea?

Which conditions should be included in the differential diagnoses of early, erythematous lesions of plaque-type morphea?

What are the differential diagnoses for Morphea?

Workup

What is the role of lab tests in the workup of morphea?

Which CBC count results suggest morphea?

Which erythrocyte sedimentation rate suggests morphea?

What is the role of autoantibodies in the evaluation of morphea?

What is the role of radiography in the workup of morphea?

What is the role of MRI in the workup of morphea?

What is the role of ultrasonography in the workup of morphea?

What is the role of laser Doppler flowmetry and infrared thermography in the workup of morphea?

What is the role of electroencephalography in the workup of morphea?

How is skin assessed in the workup of morphea?

What is the role of biopsy in the diagnosis of morphea?

Which histologic findings are characteristic of morphea?

Treatment

Which treatments are most effective for morphea?

What are the treatment options for superficial circumscribed morphea?

What are the treatment options for generalized, linear, or deep morphea?

What is the role of hydroxychloroquine and oral calcitriol in the treatment of morphea?

What is the role of phototherapies in the treatment of morphea?

Which investigational therapies have shown benefit for the treatment of morphea?

What is the role of surgery in the treatment of morphea?

Which specialists should be consulted in the treatment of morphea?

Medications

What is the role of medications in the treatment of morphea?

Which medications in the drug class Immunosuppressant Agent are used in the treatment of Morphea?

Which medications in the drug class Antirheumatic agents are used in the treatment of Morphea?

Which medications in the drug class Vitamin D analogs are used in the treatment of Morphea?

Which medications in the drug class Corticosteroids are used in the treatment of Morphea?