Dermatologic Manifestations of Eosinophilia-Myalgia Syndrome Medication

Updated: Apr 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: William D James, MD  more...
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Medication Summary

Glucocorticoids appear to benefit most patients with EMS, but many symptoms do not respond to this treatment. Usually, eosinophilia markedly decreases, and edema and pulmonary infiltrates resolve in response to glucocorticoids. Nonsteroidal anti-inflammatory agents and narcotic analgesics may be useful for the relief of severe muscle pain.



Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Prednisone (Deltasone, Orasone, Meticorten)

Prednisone may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. It stabilizes lysosomal membranes and suppresses lymphocyte and antibody production.