Congenital Patterned Leukodermas Treatment & Management

Updated: Jun 26, 2018
  • Author: Raymond E Boissy, PhD; Chief Editor: William D James, MD  more...
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Treatment

Approach Considerations

Limited medical treatment is available for abnormalities of the skin, hair, eyes, or ears that result from a paucity or absence of melanocytes. Surgical skin-grafting techniques have been developed, with variable success in establishing pigmentation. Camouflaging involved areas with skin stains or sunless self-tanning agents may be helpful to some patients. The use of sunscreens and clothing is recommended to protect against ultraviolet light–induced skin damage.

Surgery may be necessary to correct extensive craniofacial defects in patients with Waardenburg or Apert syndromes.

Colostomy may be necessary in patients with Hirschsprung syndrome and aganglionic megacolon.

Patients with congenital patterned leukodermas should be screened for skin cancer.

Patients with congenital patterned leukodermas should be routinely followed for advancement of the nonpigmentary disorders.