Vitiligo Questions & Answers

Updated: Oct 19, 2020
  • Author: Krista Roncone; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is vitiligo?

How are vitiligo lesions characterized?

Where are initial vitiligo lesions located?

What are the clinical variants of vitiligo?

How is vitiligo diagnosed?

What are the findings of microscopic exam of the skin in vitiligo?

What are histologic features of vitiligo?

What are the nonsurgical treatment options for vitiligo?

What is the role of surgery in the treatment of vitiligo?

What is vitiligo?

What is the pathophysiology of vitiligo?

What is the role of genetics in the pathophysiology of vitiligo?

What is the incidence of vitiligo in the US?

What is the global incidence of vitiligo?

How does the incidence of vitiligo vary by sex?

What is the most common age of onset for vitiligo?

Presentation

Which physical findings are characteristic of vitiligo?

What are the most common sites of vitiligo?

What are findings of body hair characteristic of vitiligo?

What is trichrome vitiligo?

What is marginal inflammatory vitiligo?

What is quadrichrome vitiligo?

How is vitiligo classified?

What is segmental vitiligo?

What is nonsegmental vitiligo?

What are the types of nonsegmental vitiligo?

What are the subtypes of generalized vitiligo?

DDX

What are the ocular abnormalities associated with vitiligo?

What are the signs and symptoms of Alezzandrini syndrome associated with vitiligo?

Which autoimmune conditions are associated with vitiligo?

What is the role of melanin in the progression of vitiligo?

What causes vitiligo in malignant melanoma?

What are the differential diagnoses for Vitiligo?

Workup

What is the role of biopsy in the workup of vitiligo?

What is the role of lab studies in the workup of vitiligo?

What are the histologic features of vitiligo?

Treatment

What are the treatment options for vitiligo?

What is the role of phototherapy in the treatment of vitiligo?

How is narrowband UV-B (NB-UVB) used to treat vitiligo?

How is psoralen photochemotherapy (PUVA) used to treat vitiligo?

What is the role of psoralen photochemotherapy (PUVA) in the treatment of vitiligo?

What is the role of laser therapy in the treatment of vitiligo?

What is the efficacy of combined excimer laser, topical tacrolimus, and short-term systemic corticosteroids in the treatment of vitiligo?

What is the role of combined khellin 4% ointment and monochromatic excimer light (MEL) in the treatment of vitiligo?

What is the role of topical corticosteroid in the treatment of vitiligo?

What is the role of calcineurin inhibitors in the treatment of vitiligo?

What is the role of vitamin D analogs in the treatment of vitiligo?

What is the role of afamelanotide in the treatment of vitiligo?

What is the role of Janus kinase (JAK) inhibitor therapy in the treatment of vitiligo?

What is the role of systemic corticosteroids in the treatment of vitiligo?

What is the role of depigmentation therapy in the treatment of vitiligo?

What are the long-term social and emotional consequences of depigmentation as a treatment of vitiligo?

How is depigmentation therapy administered for the treatment of vitiligo?

What is the role of surgery in the treatment of vitiligo?

When should surgery be considered for the treatment of vitiligo?

How is lesion stability determined in vitiligo?

What are the methods for repigmentation surgery for vitiligo?

What is the role of micropigmentation in the treatment of vitiligo?

Which specialist consultations may be needed to treat vitiligo?

What is the psychological and social effect of vitiligo?

Medications

What are the goals of drug treatment for vitiligo?

Which medications in the drug class Vitamins are used in the treatment of Vitiligo?

Which medications in the drug class Immunomodulator are used in the treatment of Vitiligo?

Which medications in the drug class Psoralens are used in the treatment of Vitiligo?

Which medications in the drug class Corticosteroids are used in the treatment of Vitiligo?

Which medications in the drug class Calcineurin Inhibitors are used in the treatment of Vitiligo?