Argyria Treatment & Management

Updated: May 13, 2022
  • Author: Kamila K Padlewska, MD, PhD; Chief Editor: William D James, MD  more...
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Medical Care

Treatment with depigmenting preparations is not satisfactory; however, according to some reports, 5% hydroquinone treatment may reduce the number of silver granules in the upper dermis and around sweat glands and diminish the number of melanocytes.

Chelation attempts to remove silver from the body have been unsuccessful.

Sunscreens and opaque cosmetics may be helpful in preventing further pigmentary darkening and aid in masking obvious discoloration.


Surgical Care

The treatment of argyria caused by colloidal silver ingestion using the Q-switched 1064-nm Nd:YAG laser has been reported, [26, 27] and a picosecond 755-nm Q-switched alexandrite laser has also been used with success for treatment. [28, 29]