Disseminate and Recurrent Infundibular Folliculitis Medication

Updated: Jun 14, 2022
  • Author: Christopher R Gorman, MD; Chief Editor: William D James, MD  more...
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Medication Summary

Emollients have been used for decades in disseminate and recurrent infundibular folliculitis, with variable success. Early reports indicated treatment with vitamin A. [9] Later, vitamin A therapy was reported to be ineffective. Several authors have reported success with isotretinoin systemic therapy. However, the standard dosing protocol has not been established.


Anti-inflammatory Agent

Clobetasol propionate (Temovate, Clobex, Cormax)

Clobetasol propionate is a class I superpotent topical steroid; it suppresses mitosis and increases synthesis of proteins that decrease inflammation and cause vasoconstriction. Clobetasol propionate decreases inflammation by stabilizing lysosomal membranes, inhibiting PMN and mast cell degranulation.