Neutrophilic Eccrine Hidradenitis Questions & Answers

1. Harrist TJ, Fine JD, Berman RS, Murphy GF, Mihm MC Jr. Neutrophilic eccrine hidradenitis. A distinctive type of neutrophilic dermatosis associated with myelogenous leukemia and chemotherapy. Arch Dermatol. 1982 Apr. 118(4):263-6. [QxMD MEDLINE Link].

2. Nelson CA, Stephen S, Ashchyan HJ, James WD, Micheletti RG, Rosenbach M. Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease. J Am Acad Dermatol. 2018 Dec. 79 (6):987-1006. [QxMD MEDLINE Link].

3. Bolognia JL, Cooper DL, Glusac EJ. Toxic erythema of chemotherapy: a useful clinical term. J Am Acad Dermatol. 2008 Sep. 59(3):524-9. [QxMD MEDLINE Link].

4. Bishnoi A, Daroach M, Aggarwal D, Radotra BD, Panda P, Parsad D. Ticagrelor induced neutrophilic eccrine hidradenitis: a unique adverse effect of a new antiplatelet drug. Postgrad Med J. 2019 May. 95 (1123):279-280. [QxMD MEDLINE Link].

5. Puar N, Scheele A, Perez Marques F, Panicker J. Neutrophilic eccrine hidradenitis secondary to pegfilgrastim in a patient with synovial sarcoma. Clin Case Rep. 2019 Mar. 7 (3):533-536. [QxMD MEDLINE Link].

6. Bassas-Vila J, Fernández-Figueras MT, Romaní J, Ferrándiz C. Infectious eccrine hidradenitis: a report of 3 cases and a review of the literature. Actas Dermosifiliogr. 2014 Mar. 105 (2):e7-12. [QxMD MEDLINE Link].

7. Barrera-Godínez A, Méndez-Flores S, Gatica-Torres M, et al. Not all that glitters is COVID-19: a case series demonstrating the need for histopathology when skin findings accompany SARS-CoV-2 infection. J Eur Acad Dermatol Venereol. 2021 May 20. [QxMD MEDLINE Link].

8. Feraru G, Dodiuk-Gad R, Krausz J, Ziv M. Infliximab-induced neutrophilic eccrine hidradenitis in a patient with hidradenitis suppurativa. Dermatol Ther. 2020 Nov. 33 (6):e13900. [QxMD MEDLINE Link].

9. Shih IH, Huang YH, Yang CH, Yang LC, Hong HS. Childhood neutrophilic eccrine hidradenitis: a clinicopathologic and immunohistochemical study of 10 patients. J Am Acad Dermatol. 2005 Jun. 52 (6):963-6. [QxMD MEDLINE Link].

10. Cohen PR. Neutrophilic dermatoses occurring in oncology patients. Int J Dermatol. 2007 Jan. 46(1):106-11. [QxMD MEDLINE Link].

11. Pierson JC, Helm TN, Taylor JS, Elston DM, Tuthill RJ. Neutrophilic eccrine hidradenitis heralding the onset of acute myelogenous leukemia. Arch Dermatol. 1993 Jun. 129(6):791-2. [QxMD MEDLINE Link].

12. Gomez Vazquez M, Peteiro C, Toribio J. Neutrophilic eccrine hidradenitis heralding the onset of chronic myelogenous leukaemia. J Eur Acad Dermatol Venereol. 2003 May. 17(3):328-30. [QxMD MEDLINE Link].

13. Saada V, Aractingi S, Leblond V, Marinho E, Frances C, Chosidow O. [Neutrophilic eccrine hidradenitis associated with relapse of acute myeloblastic leukemia]. Ann Dermatol Venereol. 1998 Jul. 125(6-7):420-2. [QxMD MEDLINE Link].

14. Bachmeyer C, Chaibi P, Aractingi S. Neutrophilic eccrine hidradenitis induced by granulocyte colony-stimulating factor. Br J Dermatol. 1998 Aug. 139(2):354-5. [QxMD MEDLINE Link].

15. Morice A, Penven K, Comoz F, Cribier B, Dompmartin A, Leroy D. [Neutrophilic eccrine hidradenitis in a healthy patient]. Ann Dermatol Venereol. 2005 Aug-Sep. 132(8-9 Pt 1):686-8. [QxMD MEDLINE Link].

16. Bilic M, Mutasim DF. Neutrophilic eccrine hidradenitis in a patient with Behçet's disease. Cutis. 2001 Aug. 68(2):107-11. [QxMD MEDLINE Link].

17. Mendiratta V, Sanke S, Chander R. Neutrophilic Eccrine Hidradenitis in a Child with Chronic Granulomatous Disease. Indian J Dermatol. 2016 Nov-Dec. 61 (6):683-684. [QxMD MEDLINE Link].

18. Templeton SF, Solomon AR, Swerlick RA. Intradermal bleomycin injections into normal human skin. A histopathologic and immunopathologic study. Arch Dermatol. 1994 May. 130(5):577-83. [QxMD MEDLINE Link].

19. EL Sayed F, Ammoury A, Chababi M, Dhaybi R, Bazex J. Neutrophilic eccrine hidradenitis to acetaminophen. J Eur Acad Dermatol Venereol. 2006 Nov. 20(10):1338-40. [QxMD MEDLINE Link].

20. Lienesch DW, Mutasim DF, Singh RR. Neutrophilic eccrine hidradenitis mimicking cutaneous vasculitis in a lupus patient: a complication of cyclophosphamide. Lupus. 2003. 12(9):707-9. [QxMD MEDLINE Link].

21. Tojo M, Iwatsuki K, Furukawa H, Takahashi M, Kaneko F. Neutrophilic eccrine hidradenitis in actinic reticuloid syndrome. Eur J Dermatol. 2002 Mar-Apr. 12(2):198-200. [QxMD MEDLINE Link].

22. Bhanu P, Santosh KV, Gondi S, Manjunath KG, Rajendaran SC, Raj N. Neutrophilic eccrine hidradenitis: a new culprit-carbamazepine. Indian J Pharmacol. 2013 Jan-Feb. 45 (1):91-2. [QxMD MEDLINE Link].

23. Turan H, Kaya E, Gurlevik Z, Erdem H, Oktay M. Neutrophilic eccrine hidradenitis induced by cetuximab. Cutan Ocul Toxicol. 2012 Jun. 31 (2):148-50. [QxMD MEDLINE Link].

24. Herms F, Franck N, Kramkimel N, Fichel F, Delaval L, Laurent-Roussel S, et al. Neutrophilic eccrine hidradenitis in 2 patients treated with BRAF inhibitors: a new cutaneous adverse event. Br J Dermatol. 2016 Dec 22. [QxMD MEDLINE Link].

25. Oscoz-Jaime S, Mitxelena-Eceiza J, Córdoba-Iturriagagoitia A. Neutrophilic eccrine hidradenitis in a patient treated with highly activity antiretroviral therapy. Med Clin (Barc). 2017 Jan 20. 148 (2):93-94. [QxMD MEDLINE Link].

26. Schmutz JL. [Neutrophilic eccrine hidradenitis and azathioprine hypersensitivity syndrome]. Ann Dermatol Venereol. 2014 Nov. 141 (11):738-9. [QxMD MEDLINE Link].

27. da Silva Sousa AC, Guedes Pereira RVA, Menezes NMBVN, Furtado AMC, Baptista AM. Neutrophilic eccrine hidradenitis in a patient with FOLFOX chemotherapy. Acta Dermatovenerol Alp Pannonica Adriat. 2018 Dec. 27 (4):207-209. [QxMD MEDLINE Link].

28. Bachmeyer C, Aractingi S. Neutrophilic eccrine hidradenitis. Clin Dermatol. 2000 May-Jun. 18(3):319-30. [QxMD MEDLINE Link].

29. Shear NH, Knowles SR, Shapiro L, Poldre P. Dapsone in prevention of recurrent neutrophilic eccrine hidradenitis. J Am Acad Dermatol. 1996 Nov. 35(5 Pt 2):819-22. [QxMD MEDLINE Link].

30. Andreu-Barasoain M, Calzado L, Salamanca J, Nuño A, Gamo R, Gomez de la Fuente E, et al. Generalized idiopathic neutrophilic eccrine hidradenitis in a 7-month-old child. J Am Acad Dermatol. 2012 Oct. 67(4):e133-4. [QxMD MEDLINE Link].

31. Kambayashi Y, Fujimura T, Yamasaki K, Aiba S. Therapy-resistant, spontaneously remitting generalized neutrophilic eccrine hidradenitis in a healthy patient decreases the expression of dermcidin in affected eccrine glands. Case Rep Dermatol. 2011 Sep. 3(3):228-34. [QxMD MEDLINE Link]. [Full Text].

32. Salik D, Kolivras A, Sass U, Huybrechts S, Dangoisse C. [Palmoplantar neutrophilic eccrine hidradenitis with general extension in a child in remission after acute lymphoblastic leukemia]. Ann Dermatol Venereol. 2014 Apr. 141 (4):285-9. [QxMD MEDLINE Link].

33. Headley CM, Ioffreda MD, Zaenglein AL. Neutrophilic eccrine hidradenitis: a case report of an unusual annular presentation. Cutis. 2005 Feb. 75(2):93-7. [QxMD MEDLINE Link].

34. Yasukawa K, Kato N, Aikawa K, Kodama K, Hamasaka A, Hata H. Neutrophilic eccrine hidradenitis with sclerodermoid change heralding the relapse of acute myelogenous leukemia: is this a paraneoplastic phenomenon?. Dermatology. 2007. 215(3):261-4. [QxMD MEDLINE Link].

35. Bardenstein DS, Haluschak J, Gerson S, Zaim MT. Neutrophilic eccrine hidradenitis simulating orbital cellulitis. Arch Ophthalmol. 1994 Nov. 112(11):1460-3. [QxMD MEDLINE Link].

36. Srivastava M, Scharf S, Meehan SA, Polsky D. Neutrophilic eccrine hidradenitis masquerading as facial cellulitis. J Am Acad Dermatol. 2007 Apr. 56(4):693-6. [QxMD MEDLINE Link].

37. Ostlere LS, Wells J, Stevens HP, Prentice G, Rustin MH. Neutrophilic eccrine hidradenitis with an unusual presentation. Br J Dermatol. 1993 Jun. 128(6):696-8. [QxMD MEDLINE Link].

38. Katayama S, Iwata H, Nomura Y, Nakamura A, Yamaguchi T, Hishimura N, et al. Case of miliaria rubra histologically showing neutrophilic eccrine hidradenitis due to hyperhidrosis induced by a catecholamine-producing neuroblastoma. J Dermatol. 2020 Mar. 47 (3):e92-e93. [QxMD MEDLINE Link].

39. Heo JY, Park TH, Kim WI, Yoon SY, Cho MK, Kim S. Case of neutrophilic eccrine hidradenitis resembling acanthosis nigricans in a patient with acute myeloid leukemia associated with azacitidine and sorafenib. J Dermatol. 2021 Apr. 48 (4):e155-e156. [QxMD MEDLINE Link].

40. Grillo E, Vano-Galvan S, Gonzalez C, Pedro J. Letter: Neutrophilic eccrine hidroadenitis with atypical findings. Dermatol Online J. 2011 Sep 15. 17(9):14. [QxMD MEDLINE Link].

41. Wlodek C, Bhatt N, Kennedy C. Two neutrophilic dermatoses captured simultaneously on histology. Dermatol Pract Concept. 2016 Jul 31. 6 (3):55-7. [QxMD MEDLINE Link].

42. Sanmartín O, Beato C, Suh-Oh HJ, Aragón I, España A, Majem M, et al. Clinical Management of Cutaneous Adverse Events in Patients on Chemotherapy: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology. Actas Dermosifiliogr. 2019 Jul - Aug. 110 (6):448-459. [QxMD MEDLINE Link].

43. Belot V, Perrinaud A, Corven C, de Muret A, Lorette G, Machet L. [Adult idiopathic neutrophilic eccrine hidradenitis treated with colchicine]. Presse Med. 2006 Oct. 35(10 Pt 1):1475-8. [QxMD MEDLINE Link].

44. Lee WJ, Kim CH, Chang SE, Lee MW, Choi JH, Moon KC, et al. Generalized idiopathic neutrophilic eccrine hidradenitis in childhood. Int J Dermatol. 2010 Jan. 49(1):75-8. [QxMD MEDLINE Link].

Joseph C Pierson, MD Dermatology Residency Program Director, University of Vermont College of Medicine

Joseph C Pierson, MD is a member of the following medical societies: Association of Professors of Dermatology, New England Dermatological Society, American Academy of Dermatology

Disclosure: Nothing to disclose.

Christine C Tam, MD Managing Member, Certified Dermatologists

Christine C Tam, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Michael J Wells, MD, FAAD Dermatologic/Mohs Surgeon, The Surgery Center at Plano Dermatology

Michael J Wells, MD, FAAD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, Texas Medical Association

Disclosure: Nothing to disclose.

Warren R Heymann, MD Head, Division of Dermatology, Professor, Department of Internal Medicine, Rutgers New Jersey Medical School

Warren R Heymann, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Professor of Pediatrics, Professor of Medicine, Rutgers New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, New York Academy of Medicine, Royal College of Physicians of Edinburgh, Sigma Xi, The Scientific Research Honor Society

Disclosure: Nothing to disclose.

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