Perioral Dermatitis Workup

Updated: Nov 13, 2020
  • Author: Hans J Kammler, MD, PhD; Chief Editor: William D James, MD  more...
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Workup

Laboratory Studies

The diagnosis is made clinically. No laboratory abnormalities can be expected.

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Other Tests

In a German study, [13] perioral dermatitis (POD) patients experienced significantly increased transepidermal water loss compared with rosacea patients and a control group, which indicated a skin barrier function disorder. This type of testing is not routinely used.

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Histologic Findings

Histologic findings are similar to those of rosacea, but the signs of actinic skin damage are generally less intense and vary according to the patient's age. Thus, a lymphohistiocytic infiltrate with perifollicular localization can be expected in all stages. A marked granulomatous inflammation and, occasionally, perifollicular abscesses may be present when pustules and papules are the dominant clinical findings.

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