Brocq Pseudopelade Medication

Updated: Mar 10, 2017
  • Author: Kendall M Egan, MD, FAAD; Chief Editor: William D James, MD  more...
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Medication

Medication Summary

The goal of pharmacotherapy in pseudopelade of Brocq is to slow disease progression. Remember that no standard therapies are available for pseudopelade of Brocq.

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Corticosteroids

Class Summary

Corticosteroids have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, these agents modify the body's immune response to diverse stimuli.

Clobetasol (Temovate)

Clobetasol is a class I superpotent topical steroid; it suppresses mitosis and increases the synthesis of proteins that decrease inflammation and cause vasoconstriction.

Fluocinonide (Fluonex, Lidex)

Fluocinonide is a high-potency topical corticosteroid that inhibits cell proliferation; it is immunosuppressive and anti-inflammatory.

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Antimalarial agents

Hydroxychloroquine (Plaquenil)

Hydroxychloroquine inhibits chemotaxis of eosinophils and locomotion of neutrophils; it impairs complement-dependent antigen-antibody reactions.

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