Congenital Hypertrichosis Lanuginosa Medication

Updated: Aug 28, 2018
  • Author: Dirk M Elston, MD; Chief Editor: William D James, MD  more...
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Medication

Medication Summary

The goal of pharmacotherapy is to improve the patient's appearance.

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Dermatologic agents

Class Summary

Agents with antiprotozoal action (eg, eflornithine) are effective in patients with hypertrichosis.

Eflornithine cream (Vaniqa cream, 13.9%)

Eflornithine cream is indicated for the reduction of unwanted facial hair in women. It interferes with ornithine decarboxylase in skin hair follicles needed for hair growth. It is not a depilatory but appears to retard hair growth to improve the condition and patient's appearance. Eflornithine cream slows hair growth and improves the appearance where applied. Improvement may be seen in 4-8 weeks to 6 months. Clinical studies show that hair returns to its previous condition 8 weeks after treatment is stopped. It has only been studied on the face and adjacent involved areas under the chin of individuals with hypertrichosis; therefore, limit use in these areas. Patients will likely need to continue hair-removal methods along with eflornithine.

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