Congenital Hypertrichosis Lanuginosa Medication

Updated: Aug 28, 2018
  • Author: Dirk M Elston, MD; Chief Editor: William D James, MD  more...
  • Print

Medication Summary

The goal of pharmacotherapy is to improve the patient's appearance.


Dermatologic agents

Class Summary

Agents with antiprotozoal action (eg, eflornithine) are effective in patients with hypertrichosis.

Eflornithine cream (Vaniqa cream, 13.9%)

Eflornithine cream is indicated for the reduction of unwanted facial hair in women. It interferes with ornithine decarboxylase in skin hair follicles needed for hair growth. It is not a depilatory but appears to retard hair growth to improve the condition and patient's appearance. Eflornithine cream slows hair growth and improves the appearance where applied. Improvement may be seen in 4-8 weeks to 6 months. Clinical studies show that hair returns to its previous condition 8 weeks after treatment is stopped. It has only been studied on the face and adjacent involved areas under the chin of individuals with hypertrichosis; therefore, limit use in these areas. Patients will likely need to continue hair-removal methods along with eflornithine.