Trichorrhexis Nodosa Workup

1. Ogunbiyi A, Ogun O, Enechukwu N. Recurrent hair loss resulting from generalized proximal trichorrhexis nodosa in a nigerian female. Int J Trichology. 2014 Apr. 6(2):83-4. [Medline]. [Full Text].

2. Lawson CN, Hollinger J, Sethi S, Rodney I, Sarkar R, Dlova N, et al. Updates in the understanding and treatments of skin & hair disorders in women of color. Int J Womens Dermatol. 2017 Mar. 3 (1 Suppl):S21-S37. [Medline].

3. Miyamoto M, Tsuboi R, Oh-I T. Case of acquired trichorrhexis nodosa: scanning electron microscopic observation. J Dermatol. 2009 Feb. 36(2):109-10. [Medline].

4. Papa CM, Mills OH Jr, Hanshaw W. Seasonal trichorrhexis nodosa. Role of cumulative damage in frayed hair. Arch Dermatol. 1972 Dec. 106(6):888-92. [Medline].

5. Marubashi Y, Yanagishita T, Muto J, Taguchi N, Sugiura K, Kawamoto Y, et al. Morphological analyses in fragility of pili torti with Björnstad syndrome. J Dermatol. 2017 Apr. 44 (4):455-458. [Medline].

6. Gonzalez AM, Borda LJ, Tosti A. Pili Annulati with Severe Trichorrhexis Nodosa: A Case Report and Review of the Literature. Skin Appendage Disord. 2019 Feb. 5 (2):114-116. [Medline].

7. Kim D, Ko JM, Kim YM, Seo GH, Kim GH, Lee BH, et al. Low prevalence of argininosuccinate lyase deficiency among inherited urea cycle disorders in Korea. J Hum Genet. 2018 May 17. [Medline].

8. Fichtel JC, Richards JA, Davis LS. Trichorrhexis nodosa secondary to argininosuccinicaciduria. Pediatr Dermatol. 2007 Jan-Feb. 24(1):25-7. [Medline].

9. Lurie R, Hodak E, Ginzburg A, David M. Trichorrhexis nodosa: a manifestation of hypothyroidism. Cutis. 1996 May. 57(5):358-9. [Medline].

10. Hartley JL, Zachos NC, Dawood B, Donowitz M, Forman J, Pollitt RJ, et al. Mutations in TTC37 Cause Trichohepatoenteric Syndrome (Phenotypic Diarrhea of Infancy). Gastroenterology. 2010 Feb 20. [Medline].

11. Cabanillas M, Torrelo A, Monteagudo B, Suárez-Amor O, Ramírez-Santos A, González-Vilas D, et al. A novel heterozygous point mutation in the p63 gene in a patient with ectodermal dysplasia associated with B-cell leukemia. Pediatr Dermatol. 2011 Nov-Dec. 28(6):707-10. [Medline].

12. Lünnemann L, Vogt A, Blume-Peytavi U, Garcia Bartels N. Hair-shaft abnormality in a 7-year-old girl. Trichorrhexis nodosa dueto biotinidase deficiency. JAMA Dermatol. 2013 Mar. 149(3):357-63. [Medline].

13. Mahendran P, George SM, Farrant PB. Trichorrhexis nodosa: a distinctive presentation after tumour necrosis factor-α inhibitor therapy. Clin Exp Dermatol. 2016 Apr. 41 (3):313-4. [Medline].

14. Mirmirani P. Ceramic flat irons: improper use leading to acquired trichorrhexis nodosa. J Am Acad Dermatol. 2010 Jan. 62(1):145-7. [Medline].

15. Usuda T, Saijo M, Tanaka K, Sato N, Uchiyama M, Kobayashi T. A Japanese trichothiodystrophy patient with XPD mutations. J Hum Genet. 2011 Jan. 56(1):77-9. [Medline].

16. Shao L, Newell B. Light microscopic hair abnormalities in children: retrospective review of 119 cases in a 10-year period. Pediatr Dev Pathol. 2014 Jan-Feb. 17(1):36-43. [Medline].

17. Lindsey SF, Tosti A. Ethnic hair disorders. Curr Probl Dermatol. 2015. 47:139-49. [Medline].

18. Sisto T, Bussoletti C, D'Amore A, Favoriti N, Fania L, Celleno L. Inability to grow long hair: a presentation of trichorrhexis nodosa. Cutis. 2015 Mar. 95(3):E15-6. [Medline].

19. Pollitt RJ, Jenner FA, Davies M. Sibs with mental and physical retardation and trichorrhexis nodosa with abnormal amino acid composition of the hair. Arch Dis Child. 1968 Apr. 43(228):211-6. [Medline].

20. Rodney IJ, Onwudiwe OC, Callender VD, Halder RM. Hair and scalp disorders in ethnic populations. J Drugs Dermatol. 2013 Apr. 12(4):420-7. [Medline].

21. Bahi-Buisson N, Kaminska A, Nabbout R, Barnerias C, Desguerre I, De Lonlay P, et al. Epilepsy in menkes disease: analysis of clinical stages. Epilepsia. 2006 Feb. 47(2):380-6. [Medline].

22. Egritas O, Dalgic B, Onder M. Tricho-hepato-enteric syndrome presenting with mild colitis. Eur J Pediatr. 2008 Nov 4. [Medline].

23. Kharkar V, Gutte R, Thakkar V, Khopkar U. Trichorrhexis nodosa with nail dystrophy: diagnosis by dermoscopy. Int J Trichology. 2011 Jul. 3(2):105-6. [Medline]. [Full Text].

24. Rudnicka L, Olszewska M, Rakowska A, Slowinska M. Trichoscopy update 2011. J Dermatol Case Rep. 2011 Dec 12. 5(4):82-8. [Medline]. [Full Text].

25. Haliasos EC, Kerner M, Jaimes-Lopez N, Rudnicka L, Zalaudek I, Malvehy J, et al. Dermoscopy for the pediatric dermatologist part I: dermoscopy of pediatric infectious and inflammatory skin lesions and hair disorders. Pediatr Dermatol. 2013 Mar-Apr. 30(2):163-71. [Medline].

26. Goulet O, Vinson C, Roquelaure B, Brousse N, Bodemer C, Cézard JP. Syndromic (phenotypic) diarrhea in early infancy. Orphanet J Rare Dis. 2008 Feb 28. 3:6. [Medline].

27. Khumalo NP, Dawber RP, Ferguson DJ. Apparent fragility of African hair is unrelated to the cystine-rich protein distribution: a cytochemical electron microscopic study. Exp Dermatol. 2005 Apr. 14(4):311-4. [Medline].

28. Liang C, Kraemer KH, Morris A, Schiffmann R, Price VH, Menefee E, et al. Characterization of tiger-tail banding and hair shaft abnormalities in trichothiodystrophy. J Am Acad Dermatol. 2005 Feb. 52(2):224-32. [Medline].

29. Cosimo QC, Daniela L, Elsa B, Carlo DV, Giuseppe F. Kinky hair, kinky vessels, and bladder diverticula in menkes disease. J Neuroimaging. 2011 Apr. 21(2):e114-6. [Medline].

30. Rakowska A, Górska R, Rudnicka L, Zadurska M. Trichoscopic Hair Evaluation in Patients with Ectodermal Dysplasia. J Pediatr. 2015 Apr 30. [Medline].

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Professor of Pediatrics, Professor of Medicine, Rutgers New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, New York Academy of Medicine, Royal College of Physicians of Edinburgh, Sigma Xi

Disclosure: Nothing to disclose.

David F Butler, MD Former Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Society for MOHS Surgery, Association of Military Dermatologists, Phi Beta Kappa

Disclosure: Nothing to disclose.

Paul Krusinski, MD Director of Dermatology, Fletcher Allen Health Care; Professor, Department of Internal Medicine, University of Vermont College of Medicine

Paul Krusinski, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Received income in an amount equal to or greater than $250 from: Elsevier; WebMD.

Leonard Sperling, MD Chair, Professor, Department of Dermatology, Uniformed Services University of the Health Sciences

Leonard Sperling, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Bryan D Seiff, MD Staff Physician, Department of Ophthalmology, NY Presbyterian Hospital-Cornell

Bryan D Seiff, MD is a member of the following medical societies: Alpha Omega Alpha

Disclosure: Nothing to disclose.

• Print this section
• Print the entire contents of
• Print the entire contents of article