Anetoderma Treatment & Management

Updated: Mar 01, 2022
  • Author: Anne Elizabeth Laumann, MBChB, MRCP(UK), FAAD; Chief Editor: Dirk M Elston, MD  more...
  • Print

Approach Considerations

To date, no effective treatment is available for anetoderma. Therapeutic options that have been used but have not shown consistent results include intralesional steroids, as well as systemic penicillin G, aspirin, phenytoin, dapsone, vitamin E, and niacin. Anecdotal reports have described topical epsilon-aminocaproic acid (an antifibrinolytic) [69] and oral colchicine [70] as potential treatments to prevent the development of new lesions.

Furthermore, isolated case reports have shown improvement of anetoderma lesions when treated with the following lasers:

  • The 10,600-nm ablative carbon dioxide fractional lasers [32, 59]
  • Pulsed-dye lasers (10,600 and 595 nm) in conjunction with the 1550-nm nonablative fractionated laser [71]

Surgical excision is an option if lesions are small and few in numbers.