Balanitis Xerotica Obliterans Differential Diagnoses

Updated: Nov 11, 2019
  • Author: Amira M Elbendary, MBBCh, MSc; Chief Editor: William D James, MD  more...
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DDx

Diagnostic Considerations

Also consider the following:

  • Phimosis
  • Balanitis
  • Buried penis
  • Zoon plasma cell balanitis

Goolamali and Pakianathan [33] reported penile carcinoma arising in balanitis xerotica obliterans (BXO) in a 46-year-old white man; thus, if BXO is suspected or has occurred in the past, penile carcinoma should be excluded during the examination.

Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a very rare papulosquamous dermatosis of the glans penis. PKMB presents in elderly, uncircumcised men as a slowly growing, coarsely scaling, micaceous, white-to-gold, laminated, well-demarcated plaque. The lesion may grow to involve the coronal sulcus and the distal penile shaft. Symptoms include phimosis, pain, and interference with sexual activity. PKMB is considered to be a premalignant condition. Nearly all reported patients have had malignant degeneration. Reported associated malignancies include SCC, verrucous carcinoma, and fibrosarcoma.

Differential Diagnoses