Cutis Laxa (Elastolysis) Treatment & Management

Updated: Apr 13, 2017
  • Author: Marc Zachary Handler, MD; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

No treatment exists to prevent disease progression, although dapsone can be used acutely to control swelling in persons with acquired cutis laxa (elastolysis), consistent with the suspected role of neutrophil elastase. Penicillamine and doxycycline are ineffective.

Cutis Laxa Internationale is an international support group for patients with cutis laxa (elastolysis).

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Surgical Care

Surgical correction of redundant skin folds, prolapses, or hernias may be undertaken. However, surgery often produces only temporary benefit.

Botulinum toxin injections are being considered for improving the aged appearance and facial defects seen in persons with cutis laxa (elastolysis). [33]

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Consultations

Consult a dermatologist for evaluation of the underlying cause of cutis laxa (elastolysis).

Consult an internal medicine specialist for evaluation of the underlying cause of cutis laxa (elastolysis) and internal organ involvement.

Cutis laxa (elastolysis) increases the risk for aortic aneurysm; therefore, regular cardiac monitoring is recommended to avert a potentially fatal aortic rupture.

Affected individuals may require a consultation with a pulmonologist.

Consultation with a geneticist is suggested, particularly for patients presenting in childhood.

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Prevention

Discontinuation of cigarette smoking is beneficial to prevent the progression of pulmonary disease.

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