Elastosis Perforans Serpiginosum Differential Diagnoses

1. Liang J, Wang D, Xu J, Chen L. Two cases of D-penicillamine-induced elastosis perforans serpiginosa. Indian J Dermatol Venereol Leprol. 2016 Jul-Aug. 82 (4):452-4. [QxMD MEDLINE Link].

2. Hashimoto K, McEvoy B, Belcher R. Ultrastructure of penicillamine-induced skin lesions. J Am Acad Dermatol. 1981 Mar. 4(3):300-15. [QxMD MEDLINE Link].

3. Langeveld-Wildschut EG, Toonstra J, van Vloten WA, Beemer FA. Familial elastosis perforans serpiginosa. Arch Dermatol. 1993 Feb. 129(2):205-7. [QxMD MEDLINE Link].

4. Rios-Buceta L, Amigo-Echenagusia A, Sols-Candelas M, Fraga-Fernandez J, Fernandez-Herrera J. Elastosis perforans serpiginosa with simultaneous onset in two sisters. Int J Dermatol. 1993 Dec. 32(12):879-81. [QxMD MEDLINE Link].

5. Espinosa PS, Baumann RJ, Vaishnav AG. Elastosis perforans serpiginosa, Down syndrome, and moyamoya disease. Pediatr Neurol. 2008 Apr. 38(4):287-8. [QxMD MEDLINE Link].

6. Venkatachalam K, Chennamsetty K. Elastosis perforans serpiginosa in a case of pseudoxanthoma elasticum: A rare association. Indian Dermatol Online J. 2016 Mar-Apr. 7 (2):103-6. [QxMD MEDLINE Link].

7. Abe R, Murase S, Nomura Y, Natuga K, Tateishi Y, Tomita Y, et al. Aquired perforating dermatosis appearing as elastosis perforans serpiginosa and perforating folliculitis. Clin Exp Dermatol. Aug/2008. 33:653-4.

8. Roest MA, Ratnavel R. Elastosis perforans serpiginosa of the penis. BJU Int. 2003 Mar. 91(4):427. [QxMD MEDLINE Link].

9. Lewis BK, Chern PL, Stone MS. Penicillamine-induced elastosis of the mucosal lip. J Am Acad Dermatol. 2009 Apr. 60(4):700-3. [QxMD MEDLINE Link].

10. Atzori L, Pinna AL, Pau M, Aste N. D-penicillamine elastosis perforans serpiginosa: description of two cases and review of the literature. Dermatol Online J. 2011 Apr 15. 17(4):3. [QxMD MEDLINE Link].

11. Fujimoto N, Akagi A, Tajima S, et al. Expression of the 67-kDa elastin receptor in perforating skin disorders. Br J Dermatol. 2002 Jan. 146(1):74-9. [QxMD MEDLINE Link].

12. Fujimoto N, Tajima S, Ishibashi A. Elastin peptides induce migration and terminal differentiation of cultured keratinocytes via 67 kDa elastin receptor in vitro: 67 kDa elastin receptor is expressed in the keratinocytes eliminating elastic materials in elastosis perforans serpiginosa. J Invest Dermatol. 2000 Oct. 115(4):633-9. [QxMD MEDLINE Link].

13. Ratnavel RC, Norris PG. Penicillamine-induced elastosis perforans serpiginosa treated successfully with isotretinoin. Dermatology. 1994. 189(1):81-3. [QxMD MEDLINE Link].

14. Outland JD, Brown TS, Callen JP. Tazarotene is an effective therapy for elastosis perforans serpiginosa. Arch Dermatol. 2002 Feb. 138(2):169-71. [QxMD MEDLINE Link].

15. Kelly SC, Purcell SM. Imiquimod therapy for elastosis perforans serpiginosa. Arch Dermatol. 2006 Jul. 142(7):829-30. [QxMD MEDLINE Link].

16. Wang D, Liang J, Xu J, Chen L. Effective treatment of d-penicillamine induced elastosis perforans serpiginosa with ALA-PDT. Photodiagnosis Photodyn Ther. 2015 Mar. 12 (1):140-2. [QxMD MEDLINE Link].

17. Tuyp EJ, McLeod WA. Elastosis perforans serpiginosa: treatment with liquid nitrogen. Int J Dermatol. 1990 Nov. 29(9):655-6. [QxMD MEDLINE Link].

18. Humphrey S, Hemmati I, Randhawa R, Crawford RI, Hong CH. Elastosis perforans serpignosa: treatment with liquid nitrogen cryotherapy and review of the literature. J Cutan Med Surg. 2010 Jan-Feb. 14(1):38-42. [QxMD MEDLINE Link].

19. Humphrey S, Hemmati I, Randhawa R, Crawford RI, Hong CH. Elastosis perforans serpignosa: treatment with liquid nitrogen cryotherapy and review of the literature. J Cutan Med Surg. 2010 Jan-Feb. 14(1):38-42. [QxMD MEDLINE Link].

20. Saxena M, Tope WD. Response of elastosis perforans serpiginosa to pulsed CO2, Er:YAG, and dye lasers. Dermatol Surg. 2003 Jun. 29(6):677-8. [QxMD MEDLINE Link].

21. Kaufman AJ. Treatment of elastosis perforans serpiginosa with the flashlamp pulsed dye laser. Dermatol Surg. 2000 Nov. 26(11):1060-2. [QxMD MEDLINE Link].

22. Kelati A, Lagrange S, Le Duff F, Lacour JP, Passeron T. Treatment of Elastosis Perforans Serpiginosa Using a Fractional Carbon Dioxide Laser. JAMA Dermatol. 2017 Oct 1. 153 (10):1063-1064. [QxMD MEDLINE Link].

Elizabeth A Liotta, MD Chief Dermatologist and Sole Proprietor, Integrated Skin Care Centers

Elizabeth A Liotta, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD Herman Beerman Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, Pennsylvania Academy of Dermatology

Disclosure: Received royalty from Lippincott Williams Wilkins for textbook editor.

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Received income in an amount equal to or greater than $250 from: Elsevier; WebMD<br/>Served as a speaker for various universities, dermatology societies, and dermatology departments.

James W Patterson, MD Professor of Pathology and Dermatology, Director of Dermatopathology, University of Virginia Medical Center

James W Patterson, MD is a member of the following medical societies: American Academy of Dermatology, American College of Physicians, American Society of Dermatopathology, Royal Society of Medicine, Society for Investigative Dermatology, United States and Canadian Academy of Pathology

Disclosure: Nothing to disclose.

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author, Willard Steck, MD† to the development and writing of this article.

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